Publications by authors named "Gui-Ning Feng"
The cancer chemodynamic therapy based on the Fenton reaction has been attracting more and more attention. However, the performance of the Fenton reaction is restricted by the unsuitable physiological pH value and inadequate HO content in the tumor microenvironment (TME). In this study, we proposed a novel method of inducing lipid peroxide (LPO) of the cancer cell membrane, whose performance is not limited by the pH value and HO in the TME.
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- The overuse of antibiotics has led to multidrug resistance, necessitating new treatment approaches for bacterial infections.
- Antimicrobial photodynamic therapy (aPDT) and silver nanoparticles show promise as effective antibacterial strategies, although high silver concentrations can harm human cells and lead to nanoparticle aggregation.
- A newly developed self-assembled supermolecular nano-carrier combines photosensitizers and silver, generating reactive oxygen species to enhance antibacterial effects while maintaining biocompatibility and reducing the risks associated with high silver concentrations.
In recent years, chemodynamic therapy (CDT) has gained increasing interest in cancer treatment. In contrast to photodynamic therapy and sonodynamic therapy, extrinsic excitations such as laser or ultrasound are not required in CDT. As a result, the CDT performance is not limited by the penetration depth of the external irritation.
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