Publications by authors named "Gui-Lin Du"
Microb Cell Fact
December 2021
Article Synopsis
- Steroid drugs are crucial for disease management, but traditional chemical synthesis methods struggle to create specific steroid intermediates effectively, prompting research into new production strategies.
- A new study focused on enhancing the production of a steroid precursor, 9-OH-4-HP, by genetically modifying Mycobacterium neoaurum to block specific metabolic pathways and improve the cell environment.
- The optimized bacterial strain yielded 3.58 g L of 9-OH-4-HP with a high purity of 97%, showcasing the potential for more efficient steroid drug precursor production in industrial applications.
