Downregulation of miR-4772-3p promotes enhanced regulatory T cell capacity in malignant pleural effusion by elevating Helios levels.

Background: Malignant pleural effusion (MPE) is a complicated condition of patients with advanced tumors. Further dissecting the microenvironment of infiltrated immune cells and malignant cells are warranted to understand the immune-evasion mechanisms of tumor development and progression.

Methods: The possible involvement of microRNAs (miRNAs) in malignant pleural fluid was investigated using small RNA sequencing.

Characteristics of H7N9 avian influenza pneumonia: a retrospective analysis of 17 cases.

Background: H7N9 avian influenza is an infection of public health concern, in part because of its high mortality rate and pandemic potential.

Aims: To describe the clinical features of H7N9 avian influenza and the response to treatment.

Methods: Clinical, radiological and histopathological data, and treatment-related of H7N9-infected patients hospitalised during 2014-2017 were extracted and analysed.