Publications by authors named "Gui-Cheng Wu"
Continuous dynamic recrystallization (CDRX) is widely acknowledged to occur during hot forming and plays a significant role in microstructure development in alloys with moderate to high stacking fault energy. In this work, the flow stress and CDRX behaviors of the TC18 alloy subjected to hot deformation across a wide range of processing conditions are studied. It is observed that deformation leads to the formation of new low-angle grain boundaries (LAGBs).
View Article and Find Full Text PDFIntroduction: Hepatitis B virus (HBV) infection is a global epidemic that can lead to several liver diseases, seriously affecting people's health. This study aimed to investigate the clinical potential of serum β-klotho (KLB) as a promising biomarker in HBV-related liver diseases.
Methodology: This study enrolled 30 patients with chronic hepatitis B (CHB), 35 with HBV-related cirrhosis, 66 with HBV-related hepatocellular carcinoma (HCC), and 48 healthy individuals.
Article Synopsis
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19 and is primarily diagnosed using real-time RT-PCR, which has some accuracy limitations.
- Researchers developed a new peptide-based luminescent immunoassay that detects IgG and IgM antibodies to improve detection.
- The immunoassay showed positive rates of 71.4% for IgG and 57.2% for IgM in confirmed patients, suggesting it could enhance COVID-19 diagnosis when used alongside RT-PCR.
Article Synopsis
- In December 2019, COVID-19 caused by the novel coronavirus emerged in Wuhan, China, with limited information on its clinical and immunological effects in children.
- A study analyzed twelve pediatric COVID-19 patients, revealing that common symptoms were cough (75%) and fever (58.3%), while children exhibited a longer incubation period (average of 8 days) compared to adults.
- The immune profiles indicated that children had higher levels of T cells and B cells, which may relate to their milder symptoms, and it is recommended that testing for SARS-CoV-2 be conducted for children with potential exposure, regardless of symptoms.
Article Synopsis
- The study analyzed the antibody responses of 285 COVID-19 patients, finding that all tested positive for IgG within 19 days of symptom onset.
- IgG and IgM antibodies either developed at the same time or one after the other, reaching stable levels within 6 days post-seroconversion.
- Serological tests could aid in diagnosing COVID-19, especially in cases with negative RT-PCR results and in detecting asymptomatic infections.
The natural history of chronic hepatitis B: a retrospective study.
Hepatobiliary Pancreat Dis Int
November 2003
Objective: To clarify the natural history of chronic hepatitis B so as to evaluate its long-term therapeutic outcome of the patients and the efficacy of antiviral drugs.
Methods: A cohort of 183 biopsy-proven chronic hepatitis B patients (mean age of 31.75+/-8.
[Long-term health-related quality of life in chronic hepatitis B patients].
Zhonghua Gan Zang Bing Za Zhi
May 2003
Objective: To evaluate their long-term outcome and the efficacy and economic significance of antiviral drugs by investigating the long-term health-related quality of life (HQL) in chronic hepatitis B (CHB) patients.
Methods: The HQL of 101 CHB patients with biopsy-proven 6 to 18 years ago and 105 persons of general population as control was studied with revised SF-36 questionnaire.
Results: The HQL in CHB patients was lower than that in general population in physical functioning, role physical, general health, mental health, and specific symptoms (mu > or = 2.