Publications by authors named "Gui-Chan Huang"
Article Synopsis
- Recent research indicates that CD8+ T cells are crucial in controlling HIV-1 reservoirs in individuals on antiretroviral therapy, although their exact mechanisms are still unclear.
- In a study of 60 virologically suppressed HIV-1 patients, certain CD8+ T cell subsets were found to correlate with levels of HIV-1 DNA and RNA, revealing that specific central and terminally differentiated memory cells behaved differently in their responses.
- The findings suggest that CCL5-secreting CD8+ T cells may play a key role in limiting HIV-1 reservoirs, paving the way for new CD8+ T cell-based treatments aimed at curing HIV-1 infection.
