Publications by authors named "Gui-Bo Yu"
Article Synopsis
- The study aimed to evaluate the expression of microRNA-182 (miRNA-182) in human osteosarcoma (OS) cells and tissues, and its impact on tumor activity.
- Researchers used quantitative PCR to measure miRNA-182 levels, then manipulated its expression in MG-63 cells with mimics and inhibitors to study effects on cell viability, proliferation, and apoptosis.
- Results showed that miRNA-182 levels were significantly higher in OS cells compared to normal cells, and its upregulation led to increased apoptosis and reduced cell viability, indicating its potential role as a tumor suppressor gene in osteosarcoma.
