Ocular manifestations and full house membranous nephropathy as a rare presentation of secondary syphilis.

Syphilis is an often-overlooked diagnosis and without timely diagnosis and treatment, can have serious repercussions. Although its prevalence had decreased with the introduction of penicillin, it has had a resurgence over the years. Discerning the proper patient population to test for syphilis should be led by a patient's risk factors.

The continued evolution of the ambulatory care pharmacy specialty: Results and analysis from the 2019 Role Delineation Study.

Objectives: Consistent with certification best practices, update the board-certified ambulatory care pharmacist (BCACP) certification content outline and examination blueprint.

Methods: Qualitative (i.e.

Association Between Personality Types and Predilection to Chronic Pain.

Chronic pain is a problem that has become common across communities. Currently there is no uniform approach for treating chronic pain. The purpose of this study was to explore whether an association exists between personality type and the predisposition to developing chronic pain.

Pain Neuroscience Education for Physical Therapy Students.

Aims: Current physical therapy curricula may not adequately address pain education. Pain Neuroscience Education (PNE) is an education tool that focuses on the influence of psychosocial pain triggers to help the patient gain better understanding of the pain experience. PNE is a potentially effective pain management intervention for sufferers of chronic pain.

Visible light as an inhibitor of Campylobacter jejuni.

Introduction: Campylobacter jejuni is a Gram-negative, microaerophilic bacteria that is the leading cause of food-borne illnesses in the United States; it frequently causes severe diarrhoea. Campylobacter jejuni has recently demonstrated antibiotic resistance; therefore, alternative methods for treating these infections must be investigated. Visible light has proven to be an effective inhibitory agent for many medically significant species of bacteria and fungi.

Effect of a multifaceted stewardship intervention on antibiotic prescribing and outcomes for acute bacterial skin and skin structure infections.

Background: Acute bacterial skin and skin structure infections (ABSSSI) are a leading cause of hospitalization, but are often treated inappropriately in the inpatient setting. A multifaceted stewardship intervention was implemented to encourage prescribing of guideline-concordant therapy (GCT).

Objective: To examine the impact of this initiative on antimicrobial prescribing practices and patient outcomes.

Chronic musculoskeletal pain and function improve with a plant-based diet.

Background: Chronic musculoskeletal pain, often debilitating, affects all genders, ethnicities, and age groups. Research suggests consumption of a plant-based diet may improve the status of persons with chronic pain. A diet rich in fruits, vegetables and whole grains has been shown to reduce chronic pain and disability associated with musculoskeletal conditions.

Degenerative Changes in Asymptomatic Subjects: A Descriptive Study Examining the Supraspinatus Using Musculoskeletal Sonography in a Young Population.

As many as 96% of persons over age 50 years may have shoulder abnormalities involving the rotator cuff. Many of these individuals remain asymptomatic. In contrast, there is limited research into the prevalence of shoulder pathology in the younger asymptomatic population.

Sensory Evaluation of Cucumbers Treated with Blue Light.

Blue light delivered at wavelengths of 405 to 470 nm has been demonstrated to inhibit growth of bacteria on foodstuffs. This study investigated the effect of a narrow band of visible light on the color, texture, and flavor (organoleptic) properties of cucumbers. Previous research in this area has focused on either broad-spectrum light or specifically the UV bands of energy.

Hydrochloric Acid Infusion for the Treatment of Metabolic Alkalosis in Surgical Intensive Care Unit Patients.

Background: Older reports of use of hydrochloric acid (HCl) infusions for treatment of metabolic alkalosis document variable dosing strategies and risk.

Objectives: This study sought to characterize use of HCl infusions in surgical intensive care unit patients for the treatment of metabolic alkalosis.

Methods: This retrospective review included patients who received a HCl infusion for >8 hours.

In vitro fungicidal effects of methylene blue at 625-nm.

The aim of the study is to confirm the effectiveness of photodynamic therapy (PDT) as a significant inhibitor of Trichophyton rubrum (T. rubrum) and to determine the most appropriate dose and rate of delivery. Trichophyton rubrum is the most common dermatophyte worldwide, responsible for the majority of superficial fungal infections.

Susceptibility of Trichopyton mentagrophytes to Visible Light Wavelengths.

Objective: To determine whether a blue light (405 nm) could inhibit the growth of Trichopyton mentagrophytes without using a photosensitizing material as part of the treatment protocol.

Design: Basic physiologic randomized trial using laboratory specimens (T mentagrophytes).

Interventions/methods: Plated on a growth medium, T mentagrophytes were exposed to 3 to 5 administrations of blue light at 20 J/cm over 28 hours.

Inactivation of Salmonella on tainted foods: using blue light to disinfect cucumbers and processed meat products.

Foodborne illness resulting from infectious organisms occurring in vegetables and processed meat is a serious health concern in the United States. Improved and cost-effective techniques for disinfection are needed. Visible light in the blue range (405 nm) was administered to processed meat that had been inoculated with .

Using near infrared light to manage symptoms associated with restless legs syndrome.

The purpose of this study was to determine whether the application of near infrared (NIR) light could positively modulate symptoms associated with restless legs syndrome (RLS). Twenty-one subjects with RLS were treated with NIR three times weekly for four weeks. Baseline measures of: (1) international restless legs syndrome rating scale (IRLSRS) score; (2) Semmes Weinstein monofilament (SWM) test; (3) visual analog pain scale (VAS); (4) ankle-brachial index (ABI); and (5) sonographic imaging of the popliteal and posterior tibial arteries were compared to post-treatment values.

Delaying the Onset of Resistance Formation: Effect of Manipulating Dose, Wavelength, and Rate of Energy Delivery of 405-, 464-, and 850-Nanometer Light for Staphylococcus aureus.

Objective: To determine whether manipulation of dose, wavelength, and rate of energy delivery could delay the onset of previously demonstrated Staphylococcus aureus resistance to blue light.

Methods: The organism was treated in vitro with 405 nm, 464 nm, and combined 464 nm and with 850 nm light emitted from a supraluminous diode (SLD) array. Doses of 9 J/cm2 and 30 J/cm2 were used.

Inactivation of Candida albicans following exposure to 624-nanometer light from a supraluminous diode array.

Objective: To determine the potential for visible light (405 or 624 nm) to produce an inhibitory effect on Candida albicans. In addition, the study sought to evaluate a series of doses in terms of their respective inhibiting capabilities.

Background Data: The authors have studied the effect of blue light on Staphylococcus aureus and found that a bactericidal outcome can be obtained with low doses of blue light.

Inactivation of mycobacterium smegmatis following exposure to 405-nanometer light from a supraluminous diode array.

Objective: To determine the potential for blue light (405 nm) to produce a bactericidal effect on Mycobacterium smegmatis. Additionally, the study sought to evaluate a series of doses in terms of their respective bactericidal capabilities.

Background Data: The effect of blue light on Staphylococcus aureus has been studied and it was found that a bactericidal outcome can be obtained with low doses of blue light.

Evidence of resistance development by Staphylococcus aureus to an in vitro, multiple stage application of 405 nm light from a supraluminous diode array.

Objective: The aim of this study was to determine whether Staphylococcus aureus could develop a resistance to 405 nm light.

Background Data: Research indicates that certain wavelengths and treatment parameters of light promote growth of bacteria; however, our earlier work indicated that blue light effectively inactivates growth of S. aureus in vitro.

In vitro bactericidal effects of 405-nm and 470-nm blue light.

Objective: The aim of this study was to determine the bactericidal effect of 405- and 470-nm light on two bacteria, Staphylococcus aureus and Pseudomonas aeruginosa, in vitro.

Background Data: It is well-known that UV light kills bacteria, but the bactericidal effects of UV may not be unique since recent studies indicate that blue light produces a somewhat similar effect. The effects of blue light seem varied depending on wavelength, dose and the nature of the bacteria, hence this study.

Effects of combined 405-nm and 880-nm light on Staphylococcus aureus and Pseudomonas aeruginosa in vitro.

Objective: The aim of this study was to determine the effect of a combination of 405-nm blue light and 880-nm infrared light on Staphylococcus aureus and Pseudomonas aeruginosa in vitro.

Background Data: Reports indicate that certain wavelengths and treatment parameters of light promote the growth of bacteria, but our earlier study indicates that light at specific wavelengths and intensities are bactericidal for specific organisms (1).

Methods: Two common aerobes, Staphylococcus aureus and Pseudomonas aeruginosa were tested because of their frequent isolation from skin infections and wounds.

Patient compliance: its relevance to the management of a patient with Charcot's foot.

This case report discusses the challenges related to the management of a diabetic patient with Charcot's foot and a neuropathic foot ulcer. The patient received good coordinated care including foot pressure measurements. The case is an example demonstrating that patient compliance is a determinant of treatment outcome.

A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values.

Monkeypox virus disease is a rare zoonosis that until recently was limited to Central Africa. We describe the clinical features of the third child in the United States reported with this newly emerging infection. This child was part of a large cluster of individuals in the Midwest infected by prairie dogs that had contracted the virus when housed with infected small mammals imported from Africa.

An evaluation of the usefulness of noncognitive variables as predictors of scores on the national physical therapy licensing examination.

This study employed a correlational design to develop a model to assess the predictive nature of noncognitive variables with regard to the physical therapy licensing examination. Fifty-seven graduates of an accredited physical therapy education program completed the Non-Cognitive Questionnaire-Revised (NCQ-R) and provided their scores from the licensing examination. Regression analysis was used to explore combinations of the eight domains of the NCQ-R as predictors of licensing examination scores.

Skin pH changes associated with iontophoresis.

Study Design: Randomized controlled trial. The researcher measuring skin pH was blinded to group assignment.

Objectives: To compare the skin surface pH changes associated with iontophoresis.