Publications by authors named "Gufen Jiang"
Objective: Despite the widespread application of non-pharmacological therapies in treating cancer-related insomnia, a comprehensive assessment of these methods is lacking. This study aims to compare the efficacy of 11 non-pharmacological interventions for cancer-related insomnia, providing a theoretical basis for clinicians in choosing treatment methods.
Methods: We searched five databases, including the Cochrane Central Register of Controlled Trials, PubMed, Embase, Wiley Library, and Web of Science, for relevant randomized controlled trials.
[Ferroptosis in male reproductive system diseases: Progress in research].
Zhonghua Nan Ke Xue
February 2024
Ferroptosis is an iron-dependent form of programmed cell death triggered by the excessive accumulation of lipid peroxides on the cell membrane. Recent studies have found that ferroptosis can be induced by exposure of the testis tissue and germ cells to some high-risk factors, accompanied by various characteristic reproductive system injuries, including changes in cell morphology, ferroptosis-related physicochemical indicators and gene expressions. This review focuses on the association of ferroptosis with male reproductive system diseases from three key aspects: iron metabolism abnormalities, Cystine/GSH/GPX4 axis imbalance, and lipid peroxidation.
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- Rosacea is a chronic inflammatory skin condition that currently has no cure, but Dendrobium polysaccharide (DOP) shows potential therapeutic effects by targeting inflammation and oxidative processes related to the disease.
- In a mouse model mimicking rosacea, DOP treatment led to improved skin symptoms and reduced inflammation, as evidenced by analysis of skin lesions and inflammatory cell counts.
- The study suggests that DOP inhibits the TLR4/NF-κB pathway, decreasing inflammation and neutrophil infiltration, making it a promising candidate for future rosacea treatments.