Publications by authors named "Guezin Ceran"

Objective: Autoimmune diseases are systemic conditions that can have negative effects on wound healing. The objective of the present study was to investigate the efficacy of combining bone marrow-derived mesenchymal stem cells (BM-MSCs), acellular dermal matrix (ADM), split-thickness skin graft (STSG), and negative-pressure wound therapy (NPWT) for treating patients with autoimmune diseases and chronic non-healing wounds.

Methods: Thirty-four patients with autoimmune diseases and non-healing chronic wounds of the lower extremities between 2012 and 2023 were included in the study.

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Objective: Vitamin D deficiency is common in adult patients undergoing allogenic hematopoietic stem cell transplantation (allo-HSCT). Since vitamin D is an important regulatory factor for the immune system, vitamin D deficiency may have effects on antitumor activity, relapse rates, graft versus host disease (GVHD) occurrence and infection rates in allo-HSCT. We aimed to investigate the effects of vitamin D levels on the outcome of allo-HSCT.

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  • Therapeutic plasma exchange is an established treatment that improves neurological symptoms by removing antibodies in patients with autoimmune neurological diseases, as shown through an 11-year study.
  • The study reviewed data from 265 patients who underwent 1,274 plasma exchange procedures, mostly for conditions like Guillain-Barré syndrome and myasthenia gravis, revealing an overall response rate of 81.3%.
  • The treatment was considered safe, with only minor complications like manageable allergic reactions and one serious case of hypertensive crisis, indicating a favorable side effect profile.
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Purpose: Assessing the prognosis of patients with malignant pleural effusion (MPE) is cruical to manage the treatment. We aimed to investigate the role of pleural fluid SUVpeak value in predicting mortality.

Methods: In our single center, prospective cohort study, we enrolled 158 patients with MPE.

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Today, to evaluate morbidity and mortality in elderly surgical patients, fragility scores, which reflect the patient's current condition rather than increasing age, are used as a basis. Our research examines the association between fragility groups, body temperature changes, and inadvertent perioperative hypothermia (IPH) in major orthopedic surgery patients. Patients over the age of 65 who underwent major orthopedic surgery were evaluated.

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  • * Evaluations before and six months after treatment revealed significant improvements in UI severity, with 43% of patients experiencing complete symptom resolution and a notable decrease in severe cases.
  • * No severe adverse events occurred; mild vaginal discharge was the only side effect, resolving within a week, indicating the treatment is both effective and safe.
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  • This study looks at how personality traits can affect opioid use disorder (OUD) and things like how hard it is to quit, how much someone is addicted, and when they first started using drugs.
  • It included 141 people with opioid addiction and 160 healthy people to compare their traits and experiences.
  • The results showed that certain feelings like sadness and anger are connected to addiction, and factors like family history and past trauma might increase the risk of starting drug use early.
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Objectives: The COVID-19 pandemic may be considered as a shared source of uncertainty. Prolonged engagement with social media regarding this uncertainty could present as a risk factor for anxiety. We sought to investigate the relationship between intolerance of uncertainty, dimensions of resilience, uncertainty source (pandemic)-related social media use, and the risk of anxiety and depression in patients with cancer.

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Background/aim: Early detection and prognosis of sepsis in critically ill children is crucial. The aim of this research was to investigate the prognostic ability of pancreatic stone protein (PSP) in validating sepsis and predicting mortality in a prospective observational study.

Materials And Methods: In a single-center study, pediatric intensive care unit patients were divided into cohorts of confirmed and suspected sepsis, as well as survivors and nonsurvivors.

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Background: Ischemia-reperfusion injury (IRI) is a phenomenon that affects transplant survival. The aim of our study was to examine the effects of IRI in isogenic and allogeneic muscle and skin transplantation models exposed to prolonged warm ischemia.

Methods: Forty-eight Lewis rats and 16 Brown-Norway rats were used to create four groups: Isogenic Inguinal Flap Transplantation (IST), Isogenic Gastrocnemius Muscle Flap Transplantation (IMT), Allogeneic Inguinal Flap Transplantation (AST), and Allogeneic Gastrocnemius Muscle Flap Transplantation (AMT).

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Background: Aim to investigate the prognostic value of neutrophil to lymphocyte ratio (NLR) at the time of diagnosis, which is an inexpensive and easily accessible parameter, compared to factors known as prognostic value (such as R-IPI and NCCN-IPI) in patients with diffuse large B-cell lymphoma (DLBCL).

Aim: Prognostic value of NLR at diagnosis in DLBCL.

Methods: A hundred (100) newly diagnosed DLBCL patients were included.

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Brain development from infancy through childhood involves complex structural and functional changes influenced by both internal and external factors. This review provides a comprehensive analysis of event and task-related brain oscillations, focusing on developmental changes across different frequency bands, including delta, theta, alpha, beta, and gamma. Electroencephalography (EEG) studies highlight that these oscillations serve as functional building blocks for sensory and cognitive processes, with significant variations observed across different developmental stages.

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  • Hair transplantation is generally safe but can lead to complications like recipient site necrosis (RSN), a rare yet serious issue; this study analyzes 18 patients who experienced RSN after the procedure from 2017 to 2023.* -
  • The research involved reviewing patient records and found that most patients were around 36 years old, with common risk factors including smoking (66.7%), hypertension (20%), and diabetes (13.3%); all patients underwent single-session follicular unit excisions.* -
  • The study highlights the importance of recognizing and managing risk factors to prevent RSN, emphasizes early treatment for better outcomes, and indicates that while many cases can be managed conservatively, some may require surgical intervention
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  • * Data were gathered from 61 patients under 18 diagnosed between January 2000 and January 2021, analyzing their primary diseases, duration until osteoporosis diagnosis, and treatment history, particularly noting the prevalence of chronic drug use.
  • * Findings highlighted that the most common underlying conditions were inflammatory diseases and neuromuscular disorders, with the majority of patients having vertebral fractures before starting bisphosphonate treatment, underscoring the severe impact of secondary osteoporosis.
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Background: Sunken eyes have become a most important target of periorbital area aesthetics. Throughout history, the aesthetics of the periorbital region have been emphasized, and various surgical techniques related to this region have been described. Most of these techniques provide only soft tissue solutions; therefore, additional surgical interventions may be required.

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Background/aim: Diabetes has become a global epidemic, necessitating effective self-management strategies. This is particularly crucial for parents of children with type 1 diabetes mellitus, as they must make numerous daily decisions and perform complex care activities. Therefore, the aim of this study was to develop a comprehensive diabetes self-management scale specifically for parents of children with type 1 diabetes.

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Background: Various reconstructive options exist for distal finger and pulp defects, including grafting and local or distant flaps. In addition to reconstructing the normal anatomical structure, preserving the sensory function of the finger is crucial. This study presents the results of using bone grafting combined with a spiral flap (BGcSF) technique for reconstructing pulp defects accompanied by bone loss.

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To overcome the different challenges to food security caused by a growing population and climate change, soybean ( (L.) Merr.) breeders are creating novel cultivars that have the potential to improve productivity while maintaining environmental sustainability.

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Background: Myelofibrosis is reported in around 40% of newly diagnosed chronic myeloid leukemia (CML) patients and have an important role in the pathobiology and prognosis of CML. This retrospective study aimed to evaluate the effects of bone marrow (BM) fibrosis on disease prognosis and the effects of specific tyrosine-kinase inhibitors (TKIs) on BM fibrosis in CML patients.

Methods: The study included 96 patients (>18 years) diagnosed with chronic phase (CP) CML.

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Aim: The present study aimed to examine the effects of a mindfulness-based stress reduction (MBSR) program and deep relaxation exercises on pregnancy-related anxiety levels.

Materials And Methods: This randomized parallel-group controlled trial was conducted with 95 pregnant women (MBSR: n = 32, deep relaxation exercises: n = 31, control: n = 32) between 1 August and 15 October 2022 with pregnant women who were registered at the pregnancy outpatient clinics of a hospital in the Southeastern Anatolia Region of Türkiye. CONSORT guidelines were followed in our study.

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Background: Social support positively affects the adaptation process of the woman to the maternal role during pregnancy and the postpartum period and increases her sensitivity to her baby. It is known that the support provided by fathers to their wives during this process positively affects their decision to breastfeed and continue.

Purpose: The aim of this study is to contribute to the literature by the Paternal Support Scale of Breastfeeding, testing its validity, reliability and psychometric properties.

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Gyrate atrophy (GA) is a hereditary condition characterized by ornithine aminotransferase deficiency-related large areas of retinal pigment epithelium and choriocapillaris lobular-shaped atrophy in the peripheral retina. In this report, we present a case of atypical presentation of GA. The aim of this report is to present two siblings, one of which was associated with a lamellar macular hole and with a history of previous diagnosis of retinitis pigmentosa.

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