Efficacy and Reliability of T-Cell-Depleted Haploidentical Stem Cell Transplantation in Hematologic Disorders: A Retrospective Study.

Background: A promising recent strategy for haploidentical transplantation is the depletion of T lymphocytes based on the selective elimination of T cells by manipulation, which enables a very low incidence of nonrelapse mortality and graft-vs-host disease. It is more expensive than conventional unmanipulated methods and requires dedicated transplant centers and sufficient stem cell processing facilities. This retrospective study aimed to evaluate the relapse, survival, and clinical data of the patients and to analyze the outcomes of the technique.

Role of vitamin D in the association between pre-stroke sleep quality and poststroke depression and anxiety.

Purpose: Poor sleep quality, mood disorders, and vitamin D deficiency are common in stroke. We investigated the association between serum vitamin D levels and pre-stroke sleep quality and the occurrence of poststroke depression (PSD) and poststroke anxiety (PSA) in acute ischemic stroke (AIS).

Methods: This prospective cross-sectional study included hospitalized patients with AIS and age- and sex-matched controls.

Associations of the neutrophil/lymphocyte ratio, monocyte/ lymphocyte ratio, and platelet/lymphocyte ratio with COVID-19 disease severity in patients with neurological symptoms: A cross-sectional monocentric study.

Objectives: Data are limited regarding the relationship of neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and platelet/ lymphocyte ratio (PLR) with neurological symptoms (NS) in COVID-19 patients. This study is the first to assess the utility of the NLR, MLR, and PLR for predicting COVID-19 severity in infected patients with NS.

Materials And Methods: Consecutive 192 PCR-positive COVID-19 patients with NS were included in this cross-sectional and prospective study.

Neurological symptoms and neuronal damage markers in acute COVID-19: Is there a correlation? A pilot study.

A wide spectrum of neurological symptoms (NS) has been described in patients with COVID-19. We examined the plasma levels of neuron-specific enolase (NSE) and neurofilament light chain (NFL) together, as neuronal damage markers, and their relationships with clinical severity in patients with NS at acute COVID-19. A total of 20 healthy controls and 59 patients with confirmed COVID-19 were enrolled in this pilot prospective study.

Patterns of COVID-19-related headache: A cross-sectional study.

Background: Headache is the most common COVID-19-related neurological symptom. We investigated the characteristics of COVID-19-related headache and their relationship with clinical severity in Kırşehir Province, Turkey.

Methods: This cross-sectional study prospectively enrolled 226 COVID-19-positive patients who developed headache during acute infection.

Plasma biomarkers of brain injury in COVID-19 patients with neurological symptoms.

Objective: Neurological symptoms (NS) were often reported in COVID-19 infection. We examined the plasma levels of glial fibrillary acidic protein (GFAP) and S100B together, as brain injury biomarkers, in relation to persistent NS in a cohort of patients with COVID-19 during the acute phase of the disease.

Methods: A total of 20 healthy controls and 58 patients with confirmed COVID-19 were enrolled in this prospective study.

Survey on Optimization Methods for LEO-Satellite-Based Networks with Applications in Future Autonomous Transportation.

Future autonomous transportation is one of the most demanding application areas in terms of connectivity, as it has to simultaneously meet stringent criteria that do not typically go hand in hand, such as high throughput, low latency, high coverage/availability, high positioning and sensing accuracies, high security and robustness to interferences, etc. In order to meet the future demands of challenging applications, such as applications relying on autonomous vehicles, terrestrial networks are no longer sufficient and are to be augmented in the future with satellite-based networks. Among the emerging satellite networks, Low Earth Orbit (LEO) networks are able to provide advantages over traditional Medium Earth Orbit (MEO) and Geo-Stationary Earth Orbit (GEO) networks in terms of signal latency, cost, and performance.

[Investigation of the Relationship of Systemic Immune-Inflammation Index, C-Reactive Protein and Interleukin-6 with Viral Dynamics in Patients with COVID-19].

Coronaviruses are enveloped, positivepolarity, single-stranded RNA viruses that can cause respiratory and gastrointestinal tract infections, less likely to cause infections with hepatic, neurological and nephrotic involvement. A novel coronavirus termed as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the city of Wuhan, China, and caused an outbreak of unusual viral pneumonia at the end of 2019. This study aimed to reveal the relationship between systemic immune-inflammation index (SII), C-reactive protein (CRP) and interleukin-6 (IL-6) and viral dynamics in COVID-19 patients.

Surface Restructuring of Thin-Film Electrodes Based on Thermal History and Its Significance for the Catalytic Activity and Stability at the Gas/Solid and Solid/Solid Interfaces.

Electrodes in solid-state energy devices are subjected to a variety of thermal treatments, from film processing to device operation at high temperatures. All these treatments influence the chemical activity and stability of the films, as the thermally induced chemical restructuring shapes the microstructure and the morphology. Here, we investigate the correlation between the oxygen reduction reaction (ORR) activity and thermal history in complex transition metal oxides, in particular, LaSrCoO (LSC64) thin films deposited by pulsed laser deposition.

[Purple Urine Bag Syndrome: A Rare Clinical Case].

Purple urine bag syndrome (PUBS) is a rare syndrome characterized by production of indigo (blue) and indirubin (red) pigments due to bacterial colonization in urinary catheter. The pathogenesis of PUBS is related to the combination of these two pigments produced from the metabolism of tryptophan. Tryptophan turns into indole by deamination, indole turns into indoxyl sulphate by hepatic conjugation and indoxyl sulphate is secreted into urine.

Cognitive assessment of patients with nonalcoholic fatty liver disease.

Objective: The aim of this study was to investigate cognitive performance for the first time in participants with nonalcoholic fatty liver disease (NAFLD) using the Montreal Cognitive Assessment (MoCA).

Participants And Methods: In total, 70 participants with NAFLD and 73 age-matched and sex-matched healthy participants were enrolled in this prospective cross-sectional study. The diagnosis of NAFLD was made on the basis of abdominal ultrasonography findings.

Role of efflux pump and OprD porin expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates.

Introduction: In recent years, the prevalence of multidrug-resistant P. aeruginosa has remarkably increased. Thus, we wanted to investigate the carbapenem resistance mechanisms and clonal relationship among 80 carbapenem-resistant P.

The association between gallstone disease and plaque in the abdominopelvic arteries.

Background: The aim of this study was to assess the atheromatous plaque, in the abdominopelvic arteries as a marker of cardiac risk in patients with or without gallstone disease (GD).

Materials And Methods: A total of 136 patients were enrolled in this cross-sectional study. Forty-eight patients had GD and the remaining 88 patients did not.

Telbivudine attenuates gentamicin-induced kidney injury in rats.

Nephrotoxicity has been associated with nucleos(t)ide analogues other than telbivudine (LdT). This study investigated the potential effects of LdT and lamivudine (LAM) on renal function in an experimental rat model of gentamicin-induced acute nephrotoxicity. A total of 28 healthy Wistar albino rats were randomly divided into four experimental groups: negative control; positive control (PC); LdT; and LAM.

Association Between Overactive Bladder and Polyneuropathy in Diabetic Patients.

Purpose: Diabetes mellitus (DM) is a chronic metabolic disorder that often leads to complications. We aimed to correlate two complications of DM, polyneuropathy and hyperactive bladder syndrome, using noninvasive measures, such as screening tests.

Methods: We included 80 female and 40 male type 2 diabetic patients in this prospective study.

Does vitamin D deficiency trigger carpal tunnel syndrome?

Objective: Vitamin D deficiencies are associated with a variety of chronic diseases. The goal of the present study was to investigate the relationship between vitamin D levels and carpal tunnel syndrome (CTS).

Methods: This study included 90 patients with mild to moderate CTS and assessed their routine serum 25-hydroxyvitamin D levels.