Publications by authors named "Guevenc Canan"

Comprehensive sex education (CSE) is linked to several favorable health outcomes yet is consistently underfunded and under-implemented. This is likely due to the perceived controversy of CSE, but research indicates that CSE in the K-12 system is widely supported in most areas of the U.S.

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The coronavirus pandemic outbreak of 2019 highlighted the critical importance of preparedness for current and future public health threats (https://www.mmv.org/mmv-open/global-health-priority-box/about-global-health-priority-box).

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Article Synopsis
  • - The study investigates how subarachnoid hemorrhage (SAH) affects oxidative stress and inflammation in the brain and heart by using Wistar Albino rats, comparing a sham group with one that experienced SAH.
  • - After 7 days, results showed increased levels of oxidative stress indicators (TOS, OSI) and inflammation markers (GFAP, NFkβ, IL-6, Cox-1) in the tissues, while antioxidant mechanisms (TAS, AKT, SIRT-1, NRF2, HO-1) were found to be reduced.
  • - The findings suggest that SAH leads to a suppression of antioxidant pathways and an enhancement of inflammatory responses, indicating a need for targeted treatments that
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Objective: Colleges and universities need effective strategies to help students develop medication-use behaviors that positively support their well-being. This pilot study evaluated the utility of Fink's Taxonomy of Significant Learning (FTSL), an evidence-based instructional strategy, to create long-lasting changes in students' well-being during a pharmacy general education course.

Participants And Methods: Using a mixed methods survey design, we assessed 84 undergraduate students' changes in self-reported well-being at three different time points (pre-intervention, post-intervention, and 6-month follow-up) through five variables (safe medication practices, general healthcare behaviors, healthcare self-efficacy, safe medication storage, and safe medication disposal).

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Article Synopsis
  • Sexual violence is a widespread issue that has significant negative effects on victims, which can be influenced by whether individuals consider their experience as rape.
  • This study examined rape acknowledgment among a diverse sample, finding that 44% acknowledged their rape, while 20% were uncertain, and 33% did not recognize their experience as rape.
  • Results showed that gender identity plays a crucial role in acknowledgment, with sexual minority transgender/nonbinary individuals being the most likely to acknowledge their rape compared to other groups, highlighting a need for further research in this area.
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This article describes the development of the Verbally Pressured Sexual Exploitation module of the Sexual Experiences Survey (SES)-Victimization (introduced by Koss et al., 2024). This module assesses the use of verbal or nonphysical, paraverbal pressure to obtain sexual acts without freely given permission.

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The Sexual Experiences Survey [SES] is considered the gold standard measure of non-consensual sexual experiences. This article introduces a new victimization version [SES-V] developed by a multidisciplinary collaboration, the first revision since 2007. The 2024 SES-V is designed to measure the construct of sexual exploitation since the 14th birthday.

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Human decision-making is increasingly supported by artificial intelligence (AI) systems. From medical imaging analysis to self-driving vehicles, AI systems are becoming organically embedded in a host of different technologies. However, incorporating such advice into decision-making entails a human rationalization of AI outputs for supporting beneficial outcomes.

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The antioxidant effect of purified phytic acid (PPA) from rice bran (rice polishing by-product) combined with sodium erythorbate (SE) was evaluated for the first time in mortadella (added with 60% mechanically separated meat), a cured product with high-fat content and highly prone to oxidation, characteristic in Brazil. PPA proved effective compared to standard analytical grade phytic acid (SPA). Two central composite rotational designs (CCRD) (A and B) were employed to investigate the influence of PPA and SE, and SPA and SE, respectively, on mortadella lipid oxidation evaluated by TBARS after 30 days at 30 °C.

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PositiveLinks (PL) is a mHealth platform to support care engagement by people with HIV (PWH). Daily reminders prompt the user to report medication adherence, mood, and daily stress. Higher response rate to PL check-ins has been associated with better suppression of viral load over 6-18 months.

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Consumers are increasingly looking for healthy foods without the addition of synthetic additives. The aim of this study was to evaluate the efficiency of coffee extracts as a natural antioxidant in fresh pork sausage. Firstly, the conditions for obtaining coffee green extracts were optimized (Central Composite Rotatable Design 2, variables: extraction time, ethanol-water ratio, and sample-solvent ratio) in an ultrasound bath (70 °C).

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Aim: Methotrexate has demonstrated efficacy in treating ectopic pregnancies. This study explores factors influencing treatment success, focusing on laboratory and ultrasonographic findings, particularly the day 4 to day 1 β-hCG level ratio.

Methods: Retrospective cohort study was conducted within patients diagnosed with tubal ectopic pregnancy.

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Objective: The cause of implantation defects in patients with recurrent implantation failure (RIF) and recurrent pregnancy loss (RPL) has not been clearly established. We aimed to evaluate the immunohistochemical changes in HOXA-11, β1 integrin, focal adhesion kinase (FAK), cluster of differentiation 44 (CD44), and extracellular matrix protein 1 (ECM1) molecules during the receptive endometrial period in patients with RIF and RPL.

Materials And Methods: This study was retrospectively conducted at a university hospital.

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Background: Mechanical power may serve as a valuable parameter for predicting ventilation-induced injury in mechanically ventilated patients. Over time, several equations have been developed to calculate power in both volume control ventilation (VCV) and pressure control ventilation (PCV). Among these equations, the linear model mechanical power equation (MP) closely approximates the reference method when applied in PCV.

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Nearly half of transgender and nonbinary (trans/NB) people will experience sexual assault in their lifetime. Beyond prevalence, little else is known about the general context in which sexual assault occurs in this community. In addition, whether and to whom trans/NB people report these experiences is also not well understood.

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Purpose: To study the performance of artificial intelligence (AI) for detecting pleural pathology on chest radiographs (CXRs) using computed tomography as ground truth.

Patients And Methods: Retrospective study of subjects undergoing CXR in various clinical settings. Computed tomography obtained within 24 hours of the CXR was used to volumetrically quantify pleural effusions (PEfs) and pneumothoraxes (Ptxs).

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Core stabilization training utilizes principles of motor learning to retrain control of the trunk muscles and lead to improvements in chronic non-specific low back pain (CNLBP). To compare the effects of biofeedback sensor and conventional physiotherapist (PT) feedback during core stabilization and activity training in patients with CNLBP. Thirty-eight patients with CNLBP were randomly assigned to Biofeedback (n = 19) or PT feedback (n = 19) groups.

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Article Synopsis
  • Visual coronary artery calcium (CAC) can be detected through routine chest CT scans, but accuracy in scoring may vary depending on the radiologist’s specialty and the use of contrast.
  • A study involving 934 patients assessed the correlation between visual CAC estimation on non-gated CT scans and actual CAC scores, finding a strong correlation overall, especially among those with moderate-to-large CAC.
  • The absence of visible CAC on non-gated scans does not necessarily indicate low cardiovascular risk, particularly in patients whose scans were enhanced with contrast or interpreted by non-specialist radiologists.
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Purpose: To perform a living systematic review and meta-analysis of randomized controlled trials comparing the effectiveness of coronary CT angiography (CCTA) and standard of care (SOC) in the evaluation of acute chest pain (ACP).

Materials And Methods: Multiple electronic databases were systematically searched, with the most recent search conducted on October 31, 2022. Studies were stratified into two groups according to the pretest probability for acute coronary syndrome (group 1 with predominantly low-to-intermediate risk vs group 2 with high risk).

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Background And Objective: Several incidental cardiovascular findings are present in a routine chest computed tomography (CT) scan, many of which do not make it to the final radiology report. However, these findings have important clinical implications, particularly providing prognosis and risk-stratification for future cardiovascular events. The purpose of this article is to review the literature on these incidental cardiovascular findings in a routine chest CT and inform the radiologist on their clinical relevance.

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Background: Do not resuscitate (DNR) is a controversial ethico-legal issue and there is no legal regulation in Turkey. Evaluating the physicians' views on DNR is critical to the current problems and contributes to legal regulation.

Objectives: To examine the views of intensive care unit residents on DNR and the sociocultural and occupational factors affecting them.

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Heteroaromatic stacking interactions are important in drug binding, supramolecular chemistry, and materials science, making protein-ligand model systems of these interactions of considerable interest. Here we studied 30 congeneric ligands that each present a distinct heteroarene for stacking between tyrosine residues at the dimer interface of procaspase-6. Complex X-ray crystal structures of 10 analogs showed that stacking geometries were well conserved, while high-accuracy computations showed that heteroarene stacking energy was well correlated with predicted overall ligand binding energies.

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Cystic fibrosis (CF) is a genetic disease that results in dysfunction of the CF transmembrane conductance regulator (CFTR) protein, which is a chloride and bicarbonate channel expressed in the apical portion of epithelial cells of various organs. Dysfunction of that protein results in diverse clinical manifestations, primarily involving the respiratory and gastrointestinal systems, impairing quality of life and reducing life expectancy. Although CF is still an incurable pathology, the therapeutic and prognostic perspectives are now totally different and much more favorable.

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.- Update articles supplement or update information found in full-length articles previously published in . These updates, written by at least one author of the previous article, provide a brief synopsis that emphasizes important new information such as technological advances, revised imaging protocols, new clinical guidelines involving imaging, or updated classification schemes.

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This review aims to summarize key articles published in the Journal of Cardiovascular Computed Tomography (JCCT) in 2022, focusing on those that had the most scientific and educational impact. The JCCT continues to expand; the number of submissions, published manuscripts, cited articles, article downloads, social media presence, and impact factor continues to grow. The articles selected by the Editorial Board of the JCCT in this review highlight the role of cardiovascular computed tomography (CCT) to detect subclinical atherosclerosis, assess the functional relevance of stenoses, and plan invasive coronary and valve procedures.

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