Publications by authors named "Guenther Turk"
Article Synopsis
- COVID-19, caused by SARS-CoV-2, is a severe global health crisis with no direct treatment available.
- Researchers conducted a high-throughput x-ray crystallography screen on repurposed drug libraries targeting the virus's main protease, which is crucial for its replication.
- They identified 37 compounds that bind to the protease and found two promising allosteric binding sites, with several compounds showing antiviral activity without toxicity in further tests.
