Migrating birds optimization-based feature selection for text classification.

Text classification tasks, particularly those involving a large number of features, pose significant challenges in effective feature selection. This research introduces a novel methodology, MBO-NB, which integrates Migrating Birds Optimization (MBO) approach with naïve Bayes as an internal classifier to address these challenges. The motivation behind this study stems from the recognized limitations of existing techniques in efficiently handling extensive feature sets.

Stereotactic radiosurgery vs. fractionated radiotherapy for large vestibular schwannomas: should FSRT be the preferred treatment?

Introduction: To evaluate the effect of fractionation and prognostic factors on local control (LC) in the treatment of vestibular schwannoma (VS).

Methods: The medical records of 104 patients with vestibular schwannoma who were treated with stereotactic radiosurgery (SRS) from January 2015 to September 2023 were retrospectively collected. SRS was performed using Cyberknife robotic lineer accelerator.

Evaluation of risk factors for postpartum cerebral venous sinus thrombosis, a multicenter retrospective observational study.

The postpartum period is a well-defined risk factor for cerebral venous sinus thrombosis (CVST). However, it is unclear which patients are at risk for CVST in the postpartum period. Thus, determining some CVST risk factors in postpartum patients may be useful for preventing the disorder in this population.

Hepatitis A virus infection and seroprevalence, Istanbul, Turkey, 2020-2023.

Background: Hepatitis A infections continue to be a major global public health problem. The epidemiology and seroprevalence of hepatitis A virus (HAV) have important public health implications. This study aimed to retrospectively examine the hepatitis A cases and hepatitis A seroprevalence in our region in our hospital with the highest number of inpatient and outpatient cases in Istanbul.

Does physical performance demonstrate patient-reported outcomes after lumbar spine surgery?

Background: Due to time and setting constraints in clinical practice, performing a comprehensive assessment with both questionnaires and physical performance tests may not be possible. This study aimed to demonstrate the relationship between physical performance and patient-reported outcomes in patients after Lumbar Spine Surgery (LSS).

Methods: A cross-sectional study was conducted with 50 participants who were followed up at least six months after LSS.

Effects of robotic surgery experience on open radical prostatectomy results: single centre & single surgeon experience.

This study aimed to evaluate the effect of robotic surgery experience on open radical prostatectomy (ORP) outcomes. We retrospectively reviewed 100 patients who underwent an ORP for clinically localised prostate cancer (PCa) performed by the same experienced surgeon. The groups included the last 50 patients before (Group 1) and the first 50 patients after (Group 2) robotic surgery experience.

Targeting the PANoptosome Using Necrostatin-1 Reduces PANoptosis and Protects the Kidney Against Ischemia-Reperfusion Injury in a Rat Model of Controlled Experimental Nonheart-Beating Donor.

Purpose: Reducing renal ischemia is crucial for the function and survival of grafts from nonheartbeat donors, as it leads to inflammatory responses and tubulointerstitial damage. The primary concern with organs from nonheartbeat donors is the long warm ischemia period and reperfusion injury following renal transplantation. This study had two main goals; one goal is to determine how Necrostatin-1 targeting the PANoptosome affects PANoptosis in the nonheart-beating donor rat model.

Increased levels of DNA methyltransferases in the placentas of women affected by Placenta Accreta Spectrum lead to aberrant DNA methylation patterns.

Placenta Accreta Spectrum (PAS) is a serious placental abnormality assosiated with significant maternal death during pregnancy. Due to its invasive characteristics resembling tumor growth, PAS is often associated with tumor-related proteins. While DNA methylation is known to regulate genes involved in development, its potential role in the development of PAS remains unclear.

Chenodeoxycholic acid alleviated the cyclosporine-induced nephrotoxicity by decreasing oxidative stress and suppressing renin-angiotensin system through AT2R and ACE2 mRNA upregulation in rats.

Oxidative stress, inflammation and renin-angiotensin system (RAS) activation play an important role in the nephrotoxicity which is caused by the long-term use of the immunosuppressive drug cyclosporine (CsA). This study investigates whether chenodeoxycholic acid (CDCA), an endogenous farnesoid X receptor (FXR) agonist with antioxidant and anti-inflammatory effects, modulates CsA nephrotoxicity. CsA (25 mg/kg/day; s.

Factors influencing the prescription of add-on long-acting muscarinic antagonists in real-world asthma management: Insights from a national registry.

Current guidelines recommend adding long-acting muscarinic antagonists (LAMAs) in patients with uncontrolled asthma, despite the use of moderate to high doses of inhaled steroid-long-acting beta agonists (ICS/LABA). This study aims to analyze the factors related to the prescription of add-on LAMA in clinical practice for asthma patients, shedding light on physicians' preferences. This study included adult asthma patients on add-on LAMA and ICS/LABA monitored for at least one year in a national registry comprising 2053 asthmatics.

A comparison of watching cartoons versus playing games as a distraction method on pain and fear of pain during peripheral intravenous cannula placement in children aged 6-9 years: A randomized experimental study.

Purpose: This study aimed to compare the effects of watching cartoons and playing games as a distraction method during peripheral intravenous cannula insertion on pain and fear of pain in children aged 6-9 years.

Design & Methods: This RCT with a parallel-group randomized experimental design was conducted between May and July 2024 in the pediatric unit of a university hospital with a tertiary referral centre. Sixty-eight children aged 6-9 years were assigned to two different groups using block randomization method (Cartoon Group = CG; n = 34, Gaming Group = GG; n = 34).

Obesity induced by a high-fat diet changes p62 protein levels in mouse reproductive organs.

Obesity is one of the major risk factor for infertility since it causes decreased quality and quantity of gametes and a disrupted uterine environment which might result in miscarriage, stillbirth, and fetal abnormal growth. Obesity induces oxidative stress which is strongly associated with infertility. The clearing of oxidative stress by autophagy is maintained through the p62/ Keap1/Nrf2 pathway.

Relaxation training via tele-rehabilitation program in patients with breast cancer receiving chemotherapy during COVID-19.

Introduction: The COVID-19 pandemic has highlighted the significance of tele-rehabilitation in granting access to physical therapy for breast cancer patients. To mitigate the adverse effects of chemotherapy, Jacobson's relaxation techniques can be performed from the comfort and safety of patients' homes. The aim of this research was to investigate the effects of relaxation exercises delivered via tele-rehabilitation in breast cancer patients receiving chemotherapy.

Effects of vibration therapy on muscle soreness and athletic performance in wheelchair basketball players.

Introduction: Vibration therapy (VT) has been widely used to increase performance and rehabilitate injuries in athletes. Delayed onset muscle soreness (DOMS), caused by excessive overload after training and competitions, leads to loss of performance.

Objective: The aim of this study was to investigate the effects of wearable local VT on muscle soreness and athletic performance in wheelchair basketball (WCB) players.

Effectiveness of subgaleal topical vancomycin powder in reducing infection rates and shunt revisions in pediatric ventriculoperitoneal shunt surgery: a promising prophylactic approach.

Purpose: This study aims to evaluate the effectiveness of two prophylactic strategies in preventing shunt infections in pediatric patients undergoing ventriculoperitoneal shunt surgery.

Methods: This retrospective study included pediatric patients who underwent ventriculoperitoneal shunt surgery between 2017 and 2024. Patients were divided into two groups based on the prophylactic method used: Group 1 (VS) where the shunt was washed with vancomycin solution before placement, and Group 2 (TVP) where vancomycin powder was applied to the subgaleal and subcutaneous tissues after shunt placement.

A narrative review of the histone acetylation and deacetylation during mammalian spermatogenesis.

Dynamic epigenetic control is essential for proper spermatogenesis. Spermatogenesis is a unique mechanism that includes recombination, meiosis, and the conversion of histones to protamines. Epigenetics refers to the ability to modify gene expression without affecting DNA strands directly and helps to regulate the dynamic gene expression throughout the differentiation process of spermatogonium stem cells.

The Effect of Peripheral Neuropathy on Disability and Anxiety.

One of the most common problems in individuals receiving neurotoxic chemotherapy is neuropathy. The study aimed to evaluate the peripheral neuropathy and the relationship between neuropathy, disability, and anxiety in patients receiving neurotoxic chemotherapy. The sample of the study consisted of individuals with cancer in the chemotherapy unit of a city hospital between March and July 2021.

Addressing social norms for adolescent timing and spacing of pregnancy in low and middle-income countries: Developing a global research agenda.

Background: Social norms shape adolescent sexual and reproductive health behaviours contributing to contraceptive and pregnancy outcomes. No global research agendas exist to guide research on adolescent social norms shifting in low- and middle-income countries (LMICs). We developed a social norms research agenda to improve adolescent healthy timing and spacing of pregnancy in LMICs.