Incidence, predictors, and outcomes of sepsis in revision total hip arthroplasty (rTHA).

Introduction: Revision total hip arthroplasty (rTHA) is increasingly common, with sepsis being a serious but rare complication. Sepsis rates in rTHA vary widely, and understanding risk factors is crucial for improving outcomes. This study aims to evaluate the incidence of sepsis following rTHA and identify preoperative and intraoperative predictors.

Adjustments of plant primary metabolism in the face of climate change.

Plant metabolism is profoundly affected by various abiotic stresses. Consequently, plants must reconfigure their metabolic networks to sustain homeostasis while synthesizing compounds that mitigate stress. This aspect, with the current intensified climate impact results in more frequent abiotic stresses on a global scale.

Evaluating the potential of abbreviated MRI protocols for liver metastasis detection: a study in colorectal cancer patients.

Purpose: To evaluate the diagnostic accuracy of different abbreviated magnetic resonance imaging (AMRI) protocols consisting of dynamic enhanced + T2-weighted imaging (T2W) and diffusion-weighted imaging (DWI) + T2W for the detection and characterization of liver metastases in a patient group with known colorectal cancer.

Material And Methods: A total of 197 hepatic lesions were retrospectively analyzed across 3 different MRI sets: AMRI-1 (dynamic enhanced + T2W), AMRI-2 (DWI + T2W), and a standard MRI protocol. The patient cohort included 100 individuals (63 males, 37 females) with a mean age of 62.

Effects of probiotic supplementation on blood lipids ın hypercholesterolemic obese patients: a randomized, double-blind, placebo-controlled pilot trial.

Objective: this trial aimed to determine the effects of probiotic supplementation on weight loss and lipid profiles in hypercholesterolemic obese patients.

Methods: ın this pilot randomized, double-blind, placebo-controlled trial, hypercholesterolemic obese patients (BMI = 30.0-35.

Characterisation of Leydig cell dysfunction in previous illicit androgen users.

Background And Objectives: A few studies have explored the impairment of pituitary gonadotroph and Leydig cell function in men who recently ceased illicit androgen use, as assessed by stimulation tests. However, the capacity of the pituitary-testis axis in previous users who discontinued androgen use years ago remains unclear. This study evaluated the pituitary-testis-axis capacity in previous illicit androgen users and nonusers.

Predictive factors of mortality in patients with abdominal trauma.

Background: Traumatic injuries, particularly abdominal trauma, are a major cause of mortality worldwide. This study aimed to evaluate predictive factors for mortality and morbidity in abdominal trauma patients using simple, rapid, and accessible clinical and laboratory parameters, with a focus on developing scoring systems for emergency department decision-making.

Methods: A retrospective cohort study was conducted in a Level 1 Trauma Center between October 2022 and March 2024.

Prevalence and clinical burden of venous thromboembolic events (VTEs) in contemporary total knee arthroplasties (TKAs) in US hospitals.

Introduction: Total knee arthroplasty (TKA) is a highly demanded procedure in orthopedic surgery, with over 1.3 million joint arthroplasties performed annually in the U.S.

Bi-allelic variants in MRPL49 cause variable clinical presentations, including sensorineural hearing loss, leukodystrophy, and ovarian insufficiency.

Combined oxidative phosphorylation deficiency (COXPD) is a rare multisystem disorder that is clinically and genetically heterogeneous. Genome sequencing identified bi-allelic MRPL49 variants in individuals from nine unrelated families with presentations ranging from Perrault syndrome (primary ovarian insufficiency and sensorineural hearing loss) to severe childhood onset of leukodystrophy, learning disability, microcephaly, and retinal dystrophy. Complexome profiling of fibroblasts from affected individuals revealed reduced levels of the small mitochondrial ribosomal subunits and a more pronounced reduction of the large mitochondrial ribosomal subunits.

Is the state anxiety level of inpatient children associated with nursing care quality? A cross-sectional study.

Aim: The aim of the research was to investigate the predictive effect of nursing care quality perceived by inpatient children aged 9 to 12 on state anxiety levels.

Methods: The research was conducted with 201 inpatient children. Data were gathered using "The Scale for Evaluating the Quality of Care from Children's Point of View (psychosocial care, physical care, and information)" and "The State Anxiety Inventory for Children.

Anemia levels in the preconception period and the first trimester of pregnancy: a national, multicentric and cross-sectional study.

Objective: The study aimed to determine the level of anemia in pregnant women in the first trimester and in the preconception period by conducting nationwide research.

Methods: The study was designed as retrospective, cross-sectional, and multicenter research. A total of 17 centers from 13 provinces were included in the study.

Investigation of the sensitivity of human A549 cells to paclitaxel and sesquiterpene lactone alantolactone via apoptosis induction.

Alantolactone (ALA), a sesquiterpene lactone compound obtained from Inula helenium root, is known to have anticancer activity in many types of cancer. Paclitaxel (PAX) is an effective first-line chemotherapeutic drug and is widely used in the treatment of lung cancer. The in vitro anticancer efficacy of combined treatment of ALA with PAX was investigated in the A549 human lung cancer cell line.

Improvement in adenoma detection rate by artificial intelligence-assisted colonoscopy: Multicenter quasi-randomized controlled trial.

Background And Study Aims: Adenoma detection rate (ADR) is a key performance measure with variability among endoscopists. Artificial intelligence (AI) in colonoscopy could reduce this variability and has shown to improve ADR. This study assessed the impact of AI on ADR among Danish endoscopists of varying experience levels.

A Quality Assessment of YouTube Videos on Chalazia: Implications for Patient Education and Healthcare Professional Involvement.

Background: YouTube has become a popular source of health information for patients. However, the quality and reliability of videos related to a chalazion, a common eyelid condition, have not yet been thoroughly evaluated.

Research Design And Methods: One hundred YouTube videos were evaluated using keywords such as "chalazion surgery" and "chalazion removal".

Shortening Psychological Scales: Semantic Similarity Matters.

In this study, we proposed a novel scale abbreviation method based on sentence embeddings and compared it to two established automatic scale abbreviation techniques. Scale abbreviation methods typically rely on administering the full scale to a large representative sample, which is often impractical in certain settings. Our approach leverages the semantic similarity among the items to select abbreviated versions of scales without requiring response data, offering a practical alternative for scale development.

Does fear of death mediate the link between intolerance of uncertainty and sleep quality? Insights from earthquake survivors in containers.

This study aims to investigate the mediating role of fear of death in the relationship between intolerance of uncertainty and sleep quality in earthquake survivors. Participants were 190 voluntary earthquake survivors (n = 64, n = 123, three of them not specified) aged between 18 and 64 years. Data collection tools were the Multidimensional Mortality Awareness Measure, Intolerance of Uncertainty Scale, Basic Scale on Insomnia Complaints/Quality of Sleep, and sociodemographic information form.

Association of Tramadol-Induced Ovarian Damage and Reproductive Dysfunction with Adenosine Triphosphate and the Protective Role of Exogenous ATP Treatment.

Tramadol, a weak opioid analgesic agent, is known to induce ovarian damage. Previous studies have held oxidative stress responsible for the adverse effects of tramadol on female reproduction. This study examined the protective effects of ATP against tramadol-induced ovarian damage and reproductive dysfunction in rats.

Associations Between Upper Extremity Activity Capacity and Strength and Post-Operative Ambulation After Geriatric Hip Fracture: A Prospective Controlled Study.

: This study aimed to investigate the effect of upper extremity activity capacity and hand grip strength on early post-operative ambulation in geriatric patients undergoing hip arthroplasty for hip fracture. : This study included patients over 70 years of age who underwent cementless bipolar hemiarthroplasty for geriatric femoral neck fracture to form a homogeneous cohort. This prospective study was terminated when the number of patients reached 102 after power analysis.

Outcomes of Metabolic and Bariatric Surgery in Populations with Obesity and Their Risk of Developing Colorectal Cancer: Where Do We Stand? An Umbrella Review on Behalf of TROGSS-The Robotic Global Surgical Society.

: Obesity is a chronic disease associated with increased risk for several cancers, including colorectal cancer (CRC), a leading cause of cancer-related mortality. The majority of CRC cases are associated with modifiable risk factors. Metabolic and bariatric surgery (MBS) is a proven, durable, and successful intervention for obesity.

Regenerative effect of lyophilized dental follicle mesenchymal stem cells and platelet-rich fibrin in skin wounds in geriatric and young rats.

The aim of this study was to investigate the regenerative effect of lyophilized dental follicle mesenchymal stem cells (DF-MSCs) combined with rat platelet-rich fibrin (PRF) on geriatric skin wounds. Human DF-MSCs which were isolated from the wisdom teeth of healthy donors and PRF were mixed and incubated in a 37 °C incubator for 1-2 h containing 1 million cells in 150 mg PRF. The mixture was suspended in a freeze-drying solution and then lyophilized.

Implementation and Outcome of a Protocol-Based Treatment for Diabetic Ketoacidosis in a Tertiary Care Pediatric Emergency Department.

Background: The standardization of clinical practice in emergency treatment of diabetic ketoacidosis (DKA) is a prerequisite for improving patient care. For this purpose, a standardized DKA protocol incorporating a two-bag system has been implemented since January 2020 in our center.

Objectives: To assess the impact of the development and utilization of the standard treatment pathway for DKA on patient outcomes.

Effect of hydrogen-producing magnesium-incorporated edible coating on Metabolomic and Volatilomic of beef meatballs.

Meat products are highly perishable and have a short shelf life. The effects of using a molecular hydrogen-producing magnesium-incorporated coating (H-P-Mg) on the color, pHysicochemical properties, deterioration, biogenic amines, free amino acid profile, and volatilomic profile of beef meatballs were evaluated. The meatballs were coated with different films as follows: group A (uncoated), group B (whey protein coating), group C (whey protein coating +7 % thyme extract), group D (whey protein coating +7 % thyme extract + Mg), and group E (whey protein coating + Mg).

Eastern Africa Origin of SAT2 Topotype XIV Foot-and-Mouth Disease Virus Outbreaks, Western Asia, 2023.

We describe detection of SAT2 topotype XIV foot-and-mouth disease viruses in western Asia during 2022-2023. Sequences show the viruses originated in eastern Africa and were introduced into western Asia on >1 occasion. The rapid spread in naive animals highlights risks for onward transmission and potential endemicity in Asia.

Correction: Engineering poly(dehydroalanine)-based gels droplet-based microfluidics: from bulk to microspheres.

Correction for 'Engineering poly(dehydroalanine)-based gels droplet-based microfluidics: from bulk to microspheres' by Hannah F. Mathews , , 2024, , 6231-6246, https://doi.org/10.

Short-Term Effects on Tear Film Following Cosmetic Botulinum Toxin Injections in Healthy Individuals.

Purpose: Botulinum toxin-A (BoNT-A) injections have become increasingly popular for cosmetic treatments in the upper face region, particularly for reducing wrinkles and achieving aesthetic improvements. While the cosmetic benefits are well-documented, the potential effects of these injections on ocular surface health and tear film dynamics remain incompletely understood. This study aimed to comprehensively investigate the impact of BoNT-A injections on tear film parameters and ocular surface health across different time intervals following treatment.

Effect of twin block on intracranial pressure.

Objectives: This study aimed to investigate the impact of Twin Block appliances on intracranial pressure (ICP) in adolescents by measuring the optic nerve sheath diameter (ONSD) using ultrasonography.

Methods: We conducted a prospective study involving 20 adolescents (8 girls and 12 boys) with skeletal mandibular retrognathia undergoing treatment with Twin Block appliances. ONSD measurements were taken at six different time points: before appliance placement (T0), 1 min after placement (T1), 10 min after placement (T2), one month after the start of treatment with twin block (T3), immediately after appliance removal (T4), and 10 min after removal (T5).