Design and Development of a Self-Report Competence Scale for The Assessment of Prehospital Health Professionals' Competence in Response to Radiological Events.

Objectives: The objective of this study was to develop a self-report scale for the assessment of the competence of pre-hospital health professionals in responding to radiological incidents.

Methods: Based on the findings of a systematic review analyzing the literature, the instrument followed the processes of item generation, expert opinion, language control, pilot study, and field testing.

Results: In the exploratory factor analysis, 48 items were excluded on the grounds of insufficient common variance (>0.

The Impact of High-Intensity Interval Training on Insulin Resistance, Oxidative Stress, and Muscle Function in a PCOS Rat Model.

Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders . This study aimed to investigate the effects of high-intensity interval training (HIIT) on insulin resistance, oxidative stress, soleus muscle function, and myokine levels in a PCOS rat model. Female rats were assigned to four groups: Control, PCOS, PCOS+Exercise, and Exercise (n=15 each).

Post-Traumatic Symptoms and Sleep Problems in Children and Adolescents after Twin Earthquakes in Turkey.

Objectives: Earthquakes cause great destruction due to their suddenness and intensity. Although all people are affected by earthquakes, children are among those most affected. Every year, millions of children and young people are exposed to many natural disasters and are affected differently.

Integration of Optical Coherence Tomography Images and Real-Life Clinical Data for Deep Learning Modeling: A Unified Approach in Prognostication of Diabetic Macular Edema.

The primary ocular effect of diabetes is diabetic retinopathy (DR), which is associated with diabetic microangiopathy. Diabetic macular edema (DME) can cause vision loss for people with DR. For this reason, deciding on the appropriate treatment and follow-up has a critical role in terms of curing the disease.

Determination of HLA Tissue Type According to the Etiology of Patients with Chronic Renal Failure.

Objective: Chronic kidney disease (CKD) is a prominent public health concern, is defined as functional and structural damage to the kidneys. This study aims to investigate the association between human leukocyte antigen (HLA) alleles individuals with CKD and the different etiological subgroups of diesease.

Methods: Genomic DNA was obtained from peripheral blood samples of 1,079 patients with retrospective CKD and 1,111 healthy control individuals.

Assessment of atmospheric volatile organic compounds at two crude oil production plants in Southeastern Türkiye.

Ambient Volatile Organic Compounds (VOCs) were investigated to determine their characteristics, Ozone Formation Potentials (OFPs), and health risks in two crude oil production plants (Nusaybin and Egil plants) in southeastern Türkiye. Benzene, toluene, ethylbenzene, m + p xylene, o xylene, and 1,3,5-trimethylbenzene were measured at eight passive sampling points in each plant. Samples were analyzed using gas chromatography coupled with a flame ionization detector and a thermal desorption.

Splenic flexure mobilization: does body topography matter?

Background: Splenic flexure mobilization can be technically challenging, and its oncological benefits remain uncertain. This study aims to explore the relationship between patient and clinical characteristics and splenic flexure mobilization time as well as the implications of prolonged splenic flexure mobilization duration.

Methods: This retrospective cohort study includes 105 patients who underwent laparoscopic distal colorectal cancer surgery between 2013 and 2018.

Effect of Estimated Individual Vitreous Volume on Intraocular Pressure Spikes After Intravitreal Anti-Vascular Endothelial Growth Factors Injection.

Introduction: The present study aimed to evaluate the effect of estimated individual vitreous volume on intraocular pressure (IOP) spikes after intravitreal anti-vascular endothelial growth factor (VEGF) injections (IVI).

Methods: Vitreous volumes (VV) of eyes were calculated using an axial length (AL) based formula AL3 x (π/6) x 0.76+0.

The Relationship of Limitations in Daily Living Activities and Other Health-Related Factors with Early Retirement.

The deterioration in health and functionality in older ages, in addition to biological changes, is affected by physical changes. Therefore, early retirement may become an inevitable choice. This study aimed to evaluate the relationship between limitations in daily living activities, mobility, and other health factors with early retirement in workers aged 50-67 in the 4th wave of the SHARE study in Europe.

Perception of Internalized Stigma in Parents of Children With Autism Spectrum Disorder: Investigating the Effects of Depression, Anxiety, and Family Functioning.

Introduction Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder that impacts communication, behavior, and social interaction. It is well-documented that parents of children with ASD often experience psychiatric conditions like anxiety and depression. Nevertheless, research on the perception of internalized stigma, family functioning, and their interconnections is scarce.

Large Language Model Ability to Translate CT and MRI Free-Text Radiology Reports Into Multiple Languages.

Background High-quality translations of radiology reports are essential for optimal patient care. Because of limited availability of human translators with medical expertise, large language models (LLMs) are a promising solution, but their ability to translate radiology reports remains largely unexplored. Purpose To evaluate the accuracy and quality of various LLMs in translating radiology reports across high-resource languages (English, Italian, French, German, and Chinese) and low-resource languages (Swedish, Turkish, Russian, Greek, and Thai).

Lateralization outcomes of bilateral inferior petrosal sinus sampling: desmopressin vs CRH.

Purpose: Bilateral inferior petrosal sinus sampling (BIPSS) is the gold standard for localizing ACTH-dependent Cushing's syndrome (CS). While corticotropin-releasing hormone (CRH) was initially used for stimulation, desmopressin has become a common alternative. This research evaluates desmopressin's effectiveness in lateralizing Cushing's disease (CD) during BIPSS compared to CRH stimulation.

The Role of Social Support in Enhancing Life Satisfaction Among Syrian Refugees in Türkiye During the COVID-19 Pandemic.

Purpose: This study investigates the role of perceived social support from family and friends in enhancing life satisfaction among Syrian refugees in Türkiye during the COVID-19 pandemic.

Materials And Methods: A cross-sectional survey was conducted among 636 Syrian refugees residing in Istanbul and Hatay provinces. The study used the Multidimensional Perceived Social Support Scale, the COVID-19 State Anxiety Sources Scale, and the Satisfaction With Life Scale.

The role of eosinophil counts and megakaryocyte nuclei for distinction of acute and chronic immune thrombocytopenic purpura.

Objective: Immune thrombocytopenic purpura (ITP), the most common cause of thrombocytopenia, is clinically classified as acute and chronic. This study aimed to distinguish between acute/chronic ITP parameters examined at diagnosis via complete blood count (CBC), peripheral blood (PB) and bone marrow aspirate (BMA) smears. It would also contribute to early treatment options, cost-effective policies, and the life quality of patients.

Evolution of Diagnostic Medical Physics Enterprise.

The roles and responsibilities of radiation safety officers (RSO), medical health physicists (MHP) and diagnostic medical physicists (DMP) have evolved significantly over the past 20 years. With the availability of enterprise software systems and aggregated data platforms for various radiologic healthcare systems, the roles of these professions are expanding beyond their original scopes in managing the Radioactive Materials License (RSO, MHP) and Machine Specific Physics Testing (DMP). Workers in medical radiation safety are transitioning from siloed workers working within their specific disciplines as new emerging technology and clinical care require these roles to evolve.

Porcupine inhibitors LGK-974 and ETC-159 inhibit Wnt/β-catenin signaling and result in inhibition of the fibrosis.

Objectives: We evaluated potential therapeutic efficacy of LGK-974 and ETC-159 in fibrotic scleroderma cells.

Methods: Primary scleroderma dermal fibroblast cells of mouse origin (SSc fibroblasts) and primary fibrotic lung fibroblast cells of human origin (CCL-191) were used in this study. PORCN inhibitors LGK-974 (S7143, 1 μM; Selleckchem, USA) and ETC-159 (S7143, 10 μM; Selleckchem, USA) were used.

Can Multiple Sclerosis-Related Symptoms Determine Sleep Disorders?

BACKGROUND: Sleep disorders are common and various in persons with multiple sclerosis (PwMS). However, their assessment and management remain in the background compared with motor symptoms. This study was conducted to better understand sleep disorders in PwMS and to analyze sleep problems and their predictive symptoms.

Oxylipins Derived from PUFAs in Cardiometabolic Diseases: Mechanism of Actions and Possible Nutritional Interactions.

Oxylipins are oxidized fatty acids, both saturated and unsaturated, formed through pathways that involve singlet oxygen or dioxygen-mediated oxygenation reactions and are primarily produced by enzyme families such as cyclooxygenases, lipoxygenases, and cytochrome P450. These lipid-based complex bioactive molecules are pivotal signal mediators, acting in a hormone-like manner in the pathophysiology of numerous diseases, especially cardiometabolic diseases via modulating plenty of mechanisms. It has been reported that omega-6 and omega-3 oxylipins are important novel biomarkers of cardiometabolic diseases.

Temporal Lobe Epilepsy Focus Detection Based on the Correlation Between Brain MR Images and EEG Recordings with a Decision Tree.

Background/objectives: In this study, a medical decision support system is presented to assist physicians in epileptic focus detection by correlating MRI and EEG data of temporal lobe epilepsy patients.

Methods: By exploiting the asymmetry in the hippocampus in MRI images and using voxel-based morphometry analysis, gray matter reduction in the temporal and limbic lobes is detected, and epileptic focus prediction is realized. In addition, an epileptic focus is also determined by calculating the asymmetry score from EEG channels.

Appraisal of inorganic and lignocellulosic organic shell wastes as a green filler in epoxy-based hybrid composites.

Hybrid composites are now becoming increasingly important regarding economic and ecological compatibility. This study presented the research results that evaluate the feasibility of using cherry pit shell (CPSh) and chicken eggshell (ChESh) natural wastes as a new hybrid filler mixture for the first time. CPSh and ChESh can reduce the composite material cost and increase the biobased content.

Relationship Between CXCL11, CXCL13, CCL2, and CCL5 Gene Expression Levels and Allograft Function in Patients Undergoing Renal Transplant.

Objectives: Chemokines are inflammatory mediators directly involved in immunological mechanisms that mediate alloimmune responses; recently, gene expression analysis studies have aroused great interest in the field of transplantation. We aimed to evaluate the predictive role of chemokine gene expression in rejection in renal transplant patients.

Materials And Methods: Our study included 91 patients who underwent living-related renal transplant.

Correlations of the Circadian Rhythmicity of Blood Pressure With Erectile Dysfunction.

Erectile dysfunction (ED) and cardiovascular diseases (CVD) share common pathophysiological mechanisms. This study aimed to assess the relationship between ED and its severity with the risk of developing CVD by analyzing changes in the circadian blood pressure (BP) rhythm. In the study, 24-h BP levels of 192 (94 with ED and 98 controls) participants with no history of CVD were evaluated using an ambulatory blood pressure monitoring (ABPM) device.