Does foreign direct investment affect environmental degradation: Evidence from largest carbon intense countries.

Foreign Direct Investment (FDI) and environmental degradation are some of the most controversial debates, especially in the context of global warming and climate change. This study aims to shed light on the impact of FDI on environmental degradation in the countries with the highest carbon dioxide (CO2) emissions, taking into account 513 country-years between the years 1996 and 2022. CO2 and the ecological footprint were used as indicators of environmental degradation.

Metal Nanoparticles for Simultaneous Use in AC Magnetic Field Hyperthermia and Magnetic Resonance Imaging.

Magnetic nanoparticles (MNPs) are produced for both diagnosis and treatment due to their simultaneous availability in magnetic resonance imaging (MRI) and magnetic hyperthermia (MHT). Extensive investigations focus on developing MNPs for individual MHT or MRI applications, but the development of MNPs for theragnostic applications has received very little attention. In this study, through efficient examination of synthesis conditions such as metal precursors, reaction parameters, and solvent choices, we aimed to optimize MNP production for effective utilization for MHT and MRI simultaneously.

Crystal Patterning from Aqueous Solutions via Solutal Instabilities.

Fluid instabilities can be harnessed for facile self-assembly of patterned structures on the nano- and microscale. Evaporative self-assembly from drops is one simple technique that enables a range of patterning behaviors due to the multitude of fluid instabilities that arise due to the simultaneous existence of temperature and solutal gradients. However, the method suffers from limited controllability over patterns that can arise and their morphology.

Alkali-Activated Binders as Sustainable Alternatives to Portland Cement and Their Resistance to Saline Water.

Alkali-activated binders have emerged as promising alternatives to Ordinary Portland Cement (OPC) due to their sustainability features and potential advantages. This study evaluates the durability properties of heat-cured fly ash (FA) and ground granulated blast-furnace slag (GGBFS) geopolymer mortars activated with sodium hydroxide, which were subjected to wet-dry cycling in saline environments. Three series of FA, a FA/GGBFS blend, and GGBFS mortars previously optimized on a compressive strength basis were investigated and compared against two control OPC mixes.

Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation.

Extracellular vesicles (EVs) are future promising therapeutics, but their instability in vivo after administration remains an important barrier to their further development. Many groups evaluated EV surface modification strategies to add a targeting group with the aim of controlling EV biodistribution. Conversely, fewer groups focused on their stabilization to obtain "stealth" allogenic EVs.

Structural screening and molecular simulation identify potential ligands against the K700E hot spot variant and functional pockets of SF3B1 to modulate splicing in myelodysplastic syndrome.

Myelodysplastic syndrome (MDS), a blood disorder with ineffective hematopoiesis and risk of transformation to acute myeloid leukemia, is characterized by recurring cytogenetic and molecular alterations. By chromosome analysis, approximately 60% of patients, carry chromosome 5 and 7 alterations, trisomy of chromosome 8 and may also present with increasingly complex karyotypes, especially in higher grade MDS (MDS with refractory anemia and increased blasts type 1 and 2). Moreover, somatic pathogenic variants in genes associated with aberrant mRNA splicing are frequently mutated with SF3B1 the most frequently mutated.

Discovering allatostatin type-C receptor specific agonists.

Currently, there is no pesticide available for the selective control of the pine processionary moth (Thaumetopoea pityocampa-specific), and conventional methods typically rely on mechanical techniques such as pheromone traps or broad-spectrum larvicidal chemicals. As climate change increases the range and dispersion capacity of crop and forest pests, outbreaks of the pine processionary occur with greater frequency and significantly impact forestry and public health. Our study is carried out to provide a T.

Citrate anticoagulation and systemic heparin anticoagulation during continuous renal replacement therapy among critically-ill children.

Bakcground: The aim of this study was to evaluate the efficacy and safety of citrate versus heparin anticoagulation for CRRT in critically-ill children.

Methods: This retrospective comparative cohort reviewed the clinical records of critically-ill children undergoing CRRT with either RCA or systemic heparin anticoagulation. The primary outcome measure was hemofilter survival time.

Anti-diabetic and anti-inflammatory bioactive hits from Matsum. stem and (Blanco) Merr. & Rolfe bark through bioassay-guided fractionation and liquid chromatography-tandem mass spectrometry.

Women have been found to be at a higher risk of morbidity and mortality from type 2 diabetes mellitus (T2DM) and asthma. α-Glucosidase inhibitors have been used to treat T2DM, and arachidonic acid 15-lipoxygenase (ALOX15) inhibitors have been suggested to be used as treatments for asthma and T2DM. Compounds that inhibit both enzymes may be studied as potential treatments for people with both T2DM and asthma.

Evaluation of the relationship between Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) score and treatment modality and mortality in patients with ileus.

AMAÇ: İleus, bağırsak geçişinin tıkanması olarak tanımlanan ve bağırsaklarda mekanik obstrüksiyon veya paralitik nedenlere bağlı olarak gelişen klinik durumdur. İnce bağırsak obstrüksiyonları primer olarak cerrahi durumlar olarak anılsada, konservatif tedavi bazı hastalarda seçilen bir tedavi protokolüdür. Bu çalışmanın amacı, ileus hastalarında HALP skorunun konservatif-cerrahi tedavi kararını, mortaliteyi ve hastanede kalış süresini belirlemede efektivitesini ve enflamasyonla ilişkili diğer parametrelere üstünlüğünü değerlendirmektir.

Early versus delayed ureterolithotripsy following obstructive acute pyelonephritis treatment.

Background And Objectives: There is no recommendation on the timing of ureterolithotripsy after the treatment of obstructive acute pyelonephritis (APN). The effect of early and delayed ureterolithotripsy on postoperative urinary tract infection (UTI) and other complications was investigated.

Methods: Patients who underwent ureterolithotripsy after obstructive APN treatment between February 2017 and August 2021 were divided into two groups, those operated during hospitalization and those operated within 3 months after discharge.

The Clinical Impact of Physical Activity on the Diagnosis of Prostate Cancer and Postprostatectomy Functional Outcomes in the Elderly.

Objectives: The effect of physical activity on prostate cancer is controversial. We aimed to investigate the effect of physical activity on prostate cancer detection and functional outcomes after radical prostatectomy.

Methods: Between 2019 and 2020, 166 patients who underwent prostate biopsy were included.

The Relationship Between Lymphocyte Subtypes with Clinicopathological Features and Prognosis of Prostate Cancer in Patients Undergoing Radical Prostatectomy.

Objective: The immune system has an essential role in the development of cancer by showing both anti-tumor and pro-tumor activities. Understanding the immune func- tion of patients with malignancy is of clinical importance for the evaluation, treatment, and prognosis of the disease. We aimed to evaluate lymphocyte subtypes in peripheral blood samples of prostate cancer patients and their relationship with clinicopathologi- cal features and prognosis.

Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy.

Ovarian cancer (OC) is the most lethal gynecologic malignancy (5-y overall survival rate, 46%). OC is generally detected when it has already spread to the peritoneal cavity (peritoneal carcinomatosis). This study investigated whether gadolinium-based nanoparticles (Gd-NPs) increase the efficacy of targeted radionuclide therapy using [Lu]Lu-DOTA-trastuzumab (an antibody against human epidermal growth factor receptor 2).

Oncologic outcomes of postoperative adjuvant versus salvage radiotherapy in prostate cancer.

Introduction: The aim of this study was to compare the long-term oncological results of patients with the diagnosis of prostate cancer who underwent open radical retropubic prostatectomy (RRP) and subsequent adjuvant (ART) or salvage radiotherapy (SRT).

Material And Methods: A total of 145 patients underwent open RRP for prostate cancer and subsequent ART or SRT postoperatively between 2010 and 2019. ART (n = 56) is defined as the group of patients with prostate-specific antigen (PSA) <0.

Factors influencing the decision-making in laparoscopic partial nephrectomy for small renal masses.

Background And Objectives: We analyzed the factors affecting the decision on surgical approach such as hilum dissection, vessel clamping, and the warm ischemia time (WIT) in laparoscopic partial nephrectomy (LPN) for small renal masses (SRMs).

Methods: Patients who underwent LPN for SRMs between 2011 and 2021 in two centers were retrospectively screened. Standardized R.

Prognostic role of intermountain risk score (IMRS) in intensive care unit patients with a diagnosis of COVID-19.

Objective: In this study, we aimed to assess the predictive value of Intermountain Risk Score (IMRS) in intensive care unit (ICU) patients with COVID-19.

Patients And Methods: Our retrospective study included the data of 194 patients who were admitted to the COVID-19 ICU of a tertiary care center. COVID-19 diagnoses were made by a positive result from a real-time reverse-transcriptase (RT) polymerase chain reaction (PCR) assay of nasal and pharyngeal swab specimens.

The effect of bioelectric impedance analysis on the success of extracorporeal shock wave lithotripsy.

Bioelectric impedance analysis (BIA) is a non-invasive method that can show the distribution of fatty and lean mass of the body. In this study, we aimed to determine the effect of BIA on extracorporeal shock wave lithotripsy (SWL) success. Our secondary aim was to determine the factors predicting transition from a single SWL session to multiple sessions.

Is There a Pathogenetic Relationship Between Alopecia Areata and Familial Mediterranean Fever?

Alopecia areata (AA) is type of autoimmune, T-cell-mediated disease with abnormal expression of MHC Class I, a common reason for non-scarring hair loss. Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease characterized by periodic fever and serositis. Various diseases and conditions that may be related to FMF have been reported.

Machine learning prediction for COVID-19 disease severity at hospital admission.

Importance: Early prognostication of patients hospitalized with COVID-19 who may require mechanical ventilation and have worse outcomes within 30 days of admission is useful for delivering appropriate clinical care and optimizing resource allocation.

Objective: To develop machine learning models to predict COVID-19 severity at the time of the hospital admission based on a single institution data.

Design, Setting, And Participants: We established a retrospective cohort of patients with COVID-19 from University of Texas Southwestern Medical Center from May 2020 to March 2022.

The role of neutrophil-albumin ratio in the diagnosis of acute appendicitis and its efficacy in predicting perforation.

Background: Acute appendicitis (AA) is one of the most common causes of abdominal pain in patients presenting to the emergency department with abdominal pain, and despite developments in radiological imaging for its diagnosis, researchers are still in pursuit of a simpler, cheaper, and safer biomarker. Our study investigated the usability of the neutrophil-albumin ratio, a biomarker that predicts prognosis in cases with severe inflammation, in diagnosing AA and anticipating perforation.

Methods: Our study is a retrospective and cross-sectional study.

The prognostic impact of tumor necrosis in non-muscle invasive bladder cancer.

Objective: We aimed to investigate the impact of tumor necrosis in non-muscle invasive bladder cancer on patients' recurrence and progression rates and survival outcomes.

Methods: This study was conducted retrospectively in a single tertiary center in Turkey. Medical records of patients who underwent transurethral resection of the bladder tumor between January 2016 and January 2021 were reviewed.