Investigation of Pressure Injuries With Visual ChatGPT Integration: A Descriptive Cross-Sectional Study.

Aim: This study aimed to assess the performance of Visual ChatGPT in staging pressure injuries using real patient images, compare it to manual staging by expert nurses, and evaluate its applicability as a supportive tool in wound care management.

Design: This study used a descriptive and comparative cross-sectional design.

Methods: The study analysed 155 patient pressure injury images from a hospital database, staged by expert nurses and Visual ChatGPT using the National Pressure Injury Advisory Panel guidelines.

Can ChatGPT pass the Turkish Orthopedics and Traumatology Board Examination? Turkish orthopedic surgeons versus artificial intelligence.

Background: Artificial intelligence has been shown to achieve successful outcomes in various orthopedic qualification examinations worldwide. This study aims to assess the performance of ChatGPT in the written section of the Turkish Orthopedics and Traumatology Board Examination, compare its results with those of candidates who took the exam, and determine whether ChatGPT is sufficient to achieve a passing score.

Methods: This retrospective observational study evaluated whether ChatGPT achieved a passing grade on 400 publicly available questions from the Turkish orthopedics qualification exam over the past four years.

An Evaluation of Neuron-Specific Enolase as a Biomarker of Neurological Impact in Pacemaker-Implanted Patients with Atrial High-Rate Episodes: An Observational Study from Turkey.

An atrial high-rate episode (AHRE) is defined according to the European Society of Cardiology (ESC) guidelines as a heart rate of ≥175 bpm lasting at least 5 min. This study aimed to evaluate whether neuron-specific enolase (NSE) levels, an indicator of neurological impact, could serve as a surrogate biomarker for silent neurological ischemia in patients with atrial high-rate episodes (AHREs). Patients with AHRE detected in a pacemaker analysis and a control group without any arrhythmias were included.

Precise Gene Editing Technologies in Retinal Applications.

Gene therapy is emerging as a promising treatment for inherited retinal diseases (IRDs). One of the first successful applications of gene therapy for IRDs was the gene replacement therapy for the RPE65 mutation. This therapy delivers a functional copy of the RPE65 gene to patients via AAV vectors, rather than targeting the mutation itself.

Efficacy of Tract Embolization on Reducing Pneumothorax in CT-Guided Transthoracic Lung Biopsies: Comparison of Saline and Autologous Blood Patch.

Rationale And Objectives: This study aimed to evaluate the effectiveness of two techniques "autologous blood patch (ABP) and saline sealing" in preventing pneumothorax during CT-guided percutaneous transthoracic lung biopsies (PTTLB).

Materials And Methods: We analyzed 218 PTTLB procedures performed on 202 patients, categorizing them into three groups: those receiving ABP, those receiving saline, and a control group with no intervention. We assessed pneumothorax and catheter drainage rates and analyzed potential risk factors, including demographics, procedural positioning, pleura-skin distance, lesion characteristics, and emphysema scores.

THE USE OF ORAL BISPHOSPHONATES IN REFRACTORY SEVERE HYPERCALCEMIA AFTER DENOSUMAB CESSATION.

Unlabelled: Denosumab,a monoclonal IgG2 antibody directed against RANK-L,is used as a neoadjuvant therapy for inoperable or metastatic giant cell tumor of bone. Many side effects like as hypocalcemia during treatment and rarely severe hypercalcemia especially in children after discontinuation of denosumab occurred. The unpredictable onset and recurrent episodes of severe hypercalcemia increase the duration of hospitalization and the risk of complications.

Electrochemical oxidative dearomatization of electron-deficient phenols using Br/Br catalysis.

An electrochemical method for the oxidative dearomatization of electron-deficient phenols by employing tetrabutylammonium bromide as a mediator under aqueous biphasic conditions is reported. This approach represents a safer alternative to the use of stoichiometric chemical oxidants and enables oxidative dearomative spirolactonization and spiroetherification reactions. Compared to previous approaches based on direct electrolysis, this strategy expands the substrate scope to electron-deficient phenols.

Serum NMR metabolomics in distinct subtypes of hematologic malignancies.

Hematologic malignancies encompass a diverse array of subtypes, contributing to substantial heterogeneity that poses challenges in predicting clinical outcomes. Leveraging the capabilities of nuclear magnetic resonance holds substantial promise in the detection of serum biomarkers and individual metabolic alterations in patients. This study involved the analysis of the sera from patients with acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin lymphoma to investigate the affected metabolites and their associated pathways.

Coexistence of phenylketonuria and tyrosinemia type 3: challenges in the dietary management.

Objectives: Phenylketonuria (PKU) and tyrosinemia type 3 (HT3) are both rare autosomal recessive disorders of phenylalanine-tyrosine metabolism. PKU is caused by a deficiency in phenylalanine hydroxylase (PAH), leading to elevated phenylalanine (Phe) and reduced tyrosine (Tyr) levels. HT3, the rarest form of tyrosinemia, is due to a deficiency in 4-hydroxyphenylpyruvate dioxygenase (HPD).

Evaluation of Coronary Artery Calcium Score (CACS) in Dipper and Non-Dipper Hypertensive Patients with Moderate and High Cardiovascular Disease Risks.

: Hypertension is typically classified into two main groups, "dipper" and "non-dipper", based on nocturnal blood pressure decline. The coronary artery calcium score (CACS) is an essential biomarker used to assess the presence and severity of coronary artery disease (CAD). This study aims to demonstrate the relationship between CACS and hypertensive patients with moderate-to-high cardiovascular disease (CVD) risk classified as either dipper or non-dipper.

Performance of Persicaria amphibia (L.) for Phytoremediation of Heavy Metals Contaminated Water.

Fast-paced global industrialization due to population growth poses negative water implications, such as pollution by heavy metals. Phytoremediation is deemed as an efficient and environmentally friendly alternative which utilizes different types of hyperaccumulator plants known as macrophytes for the removal of heavy metal pollutants from contaminated water. In this study, the removal of Cu(II), Ni(II), Pb(II), and Cd(II) heavy metal ions contaminated water was studied by using an aquatic plant, Persicaria amphibia (L.

Corrigendum to "A rare case: Transcatheter coil embolization in a patient with cystic duct stump injury following cholecystectomy" [Radiol Case Rep J. 2025;1(20) 406-409].

[This corrects the article DOI: 10.1016/j.radcr.

Soluble ST2 as a Biomarker for Predicting Right Ventricular Dysfunction in Acute Pulmonary Embolism.

Suppression of Tumorigenicity 2 (ST2), a member of the interleukin-1 (IL-1) superfamily, is recognized as an important biomarker in inflammatory responses and cardiovascular diseases. Elevated serum levels of sST2 have prognostic value, particularly in cases of cardiac stress such as heart failure and acute pulmonary embolism (APE). We aimed to assess ST2 levels as a potential biomarker for right heart dysfunction in APE patients, particularly in the context of its limited predictive value for mortality and risk stratification.

Polyneuropathy With Motor Conduction Block in POEMS.

Introduction/aims: Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is a paraneoplastic syndrome due to an underlying plasma cell dyscrasia. Polyneuropathy in POEMS syndrome may present as a subacute or chronic symmetric sensorimotor polyneuropathy, with electrophysiological features suggesting demyelination. Motor conduction block (CB), which is mostly seen in chronic inflammatory demyelinating polyneuropathy (CIDP), is considered an atypical electrophysiological feature in POEMS syndrome.

Predictive uncertainty in state-estimation drives active sensing.

Animals use active sensing movements to shape the spatiotemporal characteristics of sensory signals to better perceive their environment under varying conditions. However, the underlying mechanisms governing the generation of active sensing movements are not known. To address this, we investigated the role of active sensing movements in the refuge tracking behavior of, a species of weakly electric fish.

Effects of carvacrol on hormonal, inflammatory, antioxidant changes, and ovarian reserve in polycystic ovary syndrome in Wistar rats.

The study, which explored the effects of carvacrol on female reproductive health, particularly in terms of hormonal, inflammatory, antioxidant, and ovarian reserves in polycystic ovary syndrome, could significantly influence future treatments and clinical practice. The study, conducted on thirty-five female Wistar albino rats, was designed to mimic the conditions of polycystic ovary syndrome in humans. The rats were randomly assigned into five groups: control (C), vehicle (V), polycystic ovary syndrome (PCOS), carvacrol (CAR), and polycystic ovary syndrome + carvacrol (PCOS + CAR).

Evaluation of phenolics in the analysis of virgin olive oil using near infrared spectroscopy.

Olive oil is an indispensable part of the diet in Mediterranean regions, and is appreciated worldwide for its sensory characteristics, combining a fine aroma and pleasant flavor with the high nutritional value of specific chemical compounds. However, making rapid measurements of phenolic compounds is a major challenge for the olive oil sector. The development of a new method based on near infrared (NIR) spectroscopy may be considered an important advance for the sector, as it is rapid, low-cost, non-contaminant and non-destructive.

Inner-Bond-Cleavage Approach to Figure-Eight Macrocycles from Planar Aromatic Hydrocarbons.

Figure-eight-shaped nonplanar π-systems adopt distinctive chiral -symmetric structures, which are ideal for realizing efficient circularly polarized luminescence (CPL). However, the short-step and enantioselective synthesis of figure-eight π-systems represents a considerable challenge for the conventional bottom-up synthetic strategy. Herein, we report that the oxidative cleavage of the internal double bond of a commercially available polycyclic aromatic hydrocarbon, i.

Evaluation of silent brain injury in patients undergoing aorto-ostial coronary stent implantation.

Background: Aorto-ostial (AO) coronary interventions may be associated with multiple problems, including the potential embolization of atherothrombotic debris into the aorta and systemic circulation. Such embolization could theoretically lead to stroke or silent brain injury (SBI). In this study, we aimed to investigate whether there is an increased risk of SBI in patients undergoing AO stent implantation.

Predictive values and relationships of serum PSA levels, delta neutrophil index, neutrophil-lymphocyte ratio and other hematological parameters in patients with acute prostatitis.

Background: This study aimed to evaluate the predictive values and relationships of serum prostate-specific antigen (PSA) levels, delta neutrophil index (DNI), neutrophil-lymphocyte ratio (NLR), and other hematological parameters in patients diagnosed with acute prostatitis.

Methods: Serum PSA levels and hemogram parameters of patients diagnosed with acute prostatitis were retrospectively analyzed. Healthy patients of the same age group were assigned to the control group.

Comparative Analysis of Right vs. Left Radial Access in Percutaneous Coronary Intervention: Impact on Silent Cerebral Ischemia.

: Silent cerebral ischemia (SCI) is defined as a condition that can be detected by biochemical markers or cranial imaging methods but does not produce clinical symptom. This study aims both to compare the frequency of SCI in PCIs performed with right transradial access and left transradial access and to evaluate the influencing factors. : A prospective, single-center study included 197 patients undergoing PCI via transradial access between November 2020 and July 2022.

A Rare Cause of Hypotension in Routine Hemodialysis: Secondary Adrenal Insufficiency.

Hypotension is a common complication during hemodialysis that develops due to high ultrafiltration rate and sometimes requires intravenous fluid replacement. Intradialytic hypotension may reduce the effectiveness of dialysis and contributes to hemodialysis-related morbidity and mortality. Adrenal insufficiency is one of the causes of hypotension in the community.

Oxidative Dearomative Coupling of Electron-Deficient Arenols Using Hypohalite Catalysis.

We developed performant in situ hypohalite, especially hypobromite, catalysis for the oxidative dearomatization of low-reactivity electron-deficient arenols. The reaction scope encompasses inter- and intramolecular oxidative dearomative C-O, C-N, and C-C coupling reactions. Notably, using a chiral ammonium countercation, we achieved enantioselective hypobromite catalysis for oxidative dearomative coupling reactions.