Publications by authors named "Guelcin Aydogdu"

Background: Intraoperative challenges and complications and their course over experience in total knee arthroplasty (TKA) applications in hemophilic arthropathy have seldom been studied. Our study aimed to analyze the learning dynamics and the evolving perspective of a single arthroplasty surgeon in hemophilic knees.

Methods: The study encompassed all primary TKAs performed on hemophilic patients by a single experienced arthroplasty surgeon from May 2002 to October 2023.

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  • This meta-analysis examined the relationship between specific gene polymorphisms and endurance athlete performance, focusing on five genes believed to influence physical performance and related biological processes.
  • A total of 20 relevant studies published from 2009 to 2023 were analyzed after screening 329 articles for eligibility based on specific criteria.
  • Findings revealed no significant differences in allele and genotype frequencies between endurance athletes and control groups for most genes, but the results for the gene rs12594956 were noted as distinct.
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This study meticulously explored the oxidative stress effects induced by lanthanum (III) oxide (LaO), erbium (III) oxide (ErO), and yttrium (III) oxide (YO) nanoparticles on Artemia salina, with the objective of evaluating the environmental toxicity of rare earth oxide nanoparticles. The characterization of the nanoparticles was conducted using a suite of advanced techniques, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS), and zeta potential analysis. Artemia salina, a widely recognized model organism in ecotoxicological research, was exposed to these nanoparticles under meticulously controlled laboratory conditions.

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  • Obesity is a major health issue contributing to preventable deaths; this study explores how Vitamin B12 and Folate relate to homocysteine, which is linked to cardiovascular disease.
  • The study followed 126 patients who had bariatric surgery, analyzing various biochemical markers before and after surgery, specifically focusing on different surgical methods (RYGB and SG).
  • Results indicated significant differences in parameters like homocysteine and cholesterol levels between the surgical groups, with Vitamin B12 showing a notable impact in the RYGB group, highlighting the importance of these nutrients in managing post-surgery health outcomes.
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  • The study focuses on elderly patients (65+) who experienced thoracic trauma, particularly highlighting their increased vulnerability to falls due to age-related health issues.
  • Among 261 patients analyzed, 52% had indoor trauma, and those with indoor accidents had a higher fall risk score compared to those with outdoor accidents.
  • The findings suggest a need for targeted measures to reduce trauma-related health problems in the geriatric population as it continues to grow, emphasizing both health risks and potential financial costs.
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Background: Dietary habits are influenced by environmental factors. Among these environmental factors are the place of residence, cultural characteristics, food accessibility, and economic status, which can all contribute to changes in the dietary pattern. Migration is another factor that can influence changes in the aspects mentioned above.

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  • Psoriasis is a chronic skin condition marked by rapid skin cell growth and inflammation, often requiring various treatments ranging from topical solutions to advanced biologics.
  • Effective treatments target specific immune pathways, including the JAK/STAT pathway, with drugs like Ruxolitinib showing promise in different skin conditions, including psoriasis.
  • A case report highlights a patient with both myelofibrosis and psoriasis who was successfully treated with oral Ruxolitinib, indicating its potential in managing psoriasis vulgaris.
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Objective: To investigate the prognostic value of baseline health-related quality of life (HRQOL) for patients with intermediate-risk localized prostate cancer (IR-PCa) undergoing radical prostatectomy (RP).

Methods: 4780 patients with IR-PCa according to NCCN risk stratification were identified from a prospectively maintained database. All patients were treated with RP and had prospectively assessed baseline HRQOL.

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Water-based studies have come into prominence for illegal substance monitoring. There are limited studies on the detection of these substances in the surface waters as opposed to wastewater. This study aims to evaluate amphetamine, benzoylecgonine, cocaine, codeine, 3,4-methylenedioxy-N-methylamphetamine, morphine, and 11-nor-Δ9- tetrahydrocannabinol-9-carboxylic acid in the Küçük Menderes (KM) River at four different stations during three different periods and assess the environmental risks.

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: In childhood cancers, parents are affected psychologically as well as children. We aimed to evaluate the effect of childhood cancer type and stage, as well as elapsed time from diagnosis, on the anxiety and stress indicators among parents. : Patients aged between 0-18 years and diagnosed with cancer who were receiving chemotherapy (0-1 month, 1-6 month, 6-12 month) and completed treatment were included.

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Objective: This study investigated whether there are differences between software programs, voxel sizes, segmentation techniques, and intraoral scanners in terms of volume measurement in incisor teeth.

Study Design: Thirty extracted teeth were scanned using a 3D intraoral scanner. Physical volumes were measured using the water displacement method (WDM) as the gold standard.

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Background: Cryptococcus neoformans causes cryptococcosis, primarily affecting immunocompromised individuals, including solid-organ transplant recipients, and, less frequently, immunocompetent people.

Case: A 15-year-old male with congenital hepatic fibrosis, portal hypertension, and cirrhosis underwent orthotopic liver transplantation. He received perioperative antimicrobial and antifungal prophylaxis and continued immunosuppressive treatment.

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Patients diagnosed with amyotrophic lateral sclerosis (ALS) become dependent on caregivers to meet their daily needs and perform personal care activities. For this reason, ALS is a disease that can challenge both the patient and the caregiver physically, mentally and socially. Supporting the caregiver indirectly affects the patient's quality of care and mental well-being.

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Objectives: The influence of advancing fibrosis on graft survival in the context of pediatric liver transplantation accentuates the critical role of protocol-driven liver biopsies, a practice adopted by numerous medical centers. Consequently, the exigency for noninvasive methodologies to assess graft fibrosis assumes heightened importance when conventional clinical and laboratory parameters fail to reveal signs of liver damage.

Methods: This study aimed to assess the reliability of transient elastography (TE) in pediatric liver transplant recipients to detect graft fibrosis and compare the results of TE in patients who underwent biopsy.

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Aim: This study focused on the simultaneous detection of amphetamine, 3,4-methyl enedioxy methamphetamine, morphine, benzoylecgonine, and 11-nor-9-carboxy- tetrahydrocannabinol (Δ9-THC-COOH) in whole blood and DBS. It is aimed to select a solvent mixture for liquid-liquid extraction (LLE) technique employing LC-MS/MS. The obtained DBS results were compared with the whole blood samples results.

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Background: Forward head posture (FHP), a common postural issue, affects balance and may be linked to altered muscle activity and cervical spine alignment. This study investigated the impact of FHP on static balance and plantar pressure distribution in adults. We hypothesized that FHP would be associated with poorer balance and altered pressure distribution.

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The synthesis, characterization, and electronic properties of 4-((7-methoxyquinolin-4-yl)oxy), 4-(quinolin-2-ylthio), and 4-((7-(trifluoromethyl)quinolin-4-yl)thio) peripherally substituted oxo-titanium phthalocyanines are described for the first time. The structures of the compounds were determined by UV-Vis, FTIR, 1H NMR, and MALDI-TOF mass spectrometry. Electronic spectra and molecular and electronic properties of compounds were calculated by Density Functional Theory (DFT) and Time-Dependent Density Functional Theory (TD-DFT) methods.

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Crimean-Congo hemorrhagic fever (CCHF) is a major emerging infectious disease threat, and children are reported to have a milder disease course compared with adults, in contrast to other viral hemorrhagic fevers. The aim of this study was to compare adult and pediatric patients with CCHF to improve understanding of pathogenesis and the natural history of the disease. A retrospective analysis of all children and adults admitted with confirmed CCHF between 2011 and 2020.

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