Differentiation of benign and malignant adnexal masses: value of a morphologic scoring system.

Objective: The purpose of this study was to assess the value of conventional gray-scale ultrasonography, based on a morphologic scoring system, in the differential diagnosis of malignant and benign adnexal tumors.

Material And Methods: A total of 58 adnexal masses in 51 patients were classified prospectively as suggestive of malignant or benign, on the basis of gray-scale ultrasonographic morphology. The results were correlated with histopathological diagnosis.

p53 and mdm2 as prognostic indicators in patients with epithelial ovarian cancer: a multivariate analysis.

Objective: The aim of the study was to investigate the prognostic significance of p53 and mdm2 protein expressions in epithelial ovarian cancer and their relationship with the clinicopathological variables.

Methods: Tumor biopsy specimens from 82 patients who were homogenously treated were examined immunohistochemically for expression of p53 and mdm2 proteins. Univariate and multivariate analyses were performed for prognostic factors, and correlations with clinicopathological parameters were examined.

Microleakage of endodontically treated teeth restored with prefabricated posts and tooth-colored restorative materials.

This study evaluated the microleakage of endodontically treated teeth restored with prefabricated dowels and tooth-colored restoratives (Solitaire, Surefil, Filtek P60, Admira, Z-100) as core materials with and without the use of a flowable composite liner. A total of 200 extracted premolars were endodontically treated and prepared for post-core restorations. Prefabricated posts were inserted and cemented with resin cement into the root canals.

Value of color Doppler ultrasonography in the evaluation of orbital vascular flow in end-stage renal disease patients undergoing hemodialysis.

Purpose: To evaluate choroidal and retinal vascular flow dynamics by means of color Doppler ultrasonography in patients with end-stage renal disease undergoing hemodialysis and to compare these findings with healthy controls.

Material And Methods: Color Doppler ultrasonography and spectral analysis of nasal and temporal posterior ciliary and central retinal artery flow of both eyes were performed in 20 patients (40 eyes) and 22 controls (44 eyes) to assess peak systolic flow velocity, end-diastolic flow velocity, and resistive indices (RI). Patients with hypertension, diabetes mellitus, and any cardiac pathology were not included in the study.

The relationship between expression of Ku70 and survival in irradiated patients with endometrial carcinoma.

Objective: To investigate the prognostic value of Ku70 protein expression in patients with endometrial cancer and to examine the correlation between Ku70 expression and established prognostic factors.

Methods: Ku70 immunoreactivity was determined by an immunohistochemical technique in a series of 81 patients with stages I-III primary endometrial carcinoma. The prognostic value of Ku70 expression was also studied in 74 patients who had been followed for at least 1 year or until death.

The short-term effect of nifedipine tocolysis on placental, fetal cerebral and atrioventricular Doppler waveforms.

Objective: To evaluate the effect of nifedipine on placental and fetal middle cerebral and atrioventricular Doppler waveforms.

Methods: Doppler waveforms of uterine (UtA), umbilical (UA) and middle cerebral (MCA) arteries and both atrioventricular valves were measured from 21 pregnant women/fetuses prior to and during nifedipine therapy for preterm labor. Maternal and fetal heart rates (FHR), maternal systolic and diastolic blood pressure, the Doppler pulsatility index and systolic/diastolic ratio of the UtA, UA and MCA were measured.

Endobronchial stenting in a two-month-old infant with bronchial compression secondary to tetralogy of Fallot and absent pulmonary valve.

Bronchial compression due to pulmonary artery dilation is an important problem in infants with congenital heart disease, and can complicate the postoperative course. In recent years, airway stenting has become a popular treatment for these cases. We achieved success with endobronchial stenting in a two-month-old infant with bronchial compression caused by a dilated pulmonary artery.

Cardiac tamponade in a newborn because of umbilical venous catheterization: is correct position safe?

Cardiac tamponade is a rare but life-threatening complication of umbilical venous catheterization in the newborn. Most complications from central venous catheters are related to incorrect position of the catheter and it is emphasized to confirm the position of the catheter tip after placement in order to avoid possible complications. We present an unusual complication of cardiac tamponade because of umbilical venous catheterization in a term newborn which is extremely rare with correct location of the catheter tip at the junction of inferior vena cava and right atrium.

Regression of endometrial explants in rats treated with the cyclooxygenase-2 inhibitor rofecoxib.

Objective: To investigate the effects of cyclooxygenase-2 (COX-2) inhibitor rofecoxib on endometrial explants and on peritoneal vascular endothelial growth factor (VEGF) levels in the rat endometriosis model.

Design: Prospective, placebo-controlled study.

Setting: Laboratory at Dokuz Eylül University.

Watermelon as a New Host of Pseudomonas viridiflava, Causal Agent of Leaf and Stem Necrosis, Discovered in Turkey.

Severe leaf and stem necrosis symptoms were observed on watermelon seedlings (Citrullus lanatus cv. Euroca) in Adana, Turkey during a warm and humid period in January 2004. Streak-plate isolations were made from leaf and stem lesions on King's medium B.

Does fetal gender affect cytotrophoblast cell activity in the human term placenta? Correlation with maternal hCG levels.

Background: Pregnant women with female fetuses have higher maternal serum human chorionic gonadotropin (hCG) levels than pregnant women with male fetuses. Ki-67, a cell proliferation and activity marker, is confined mostly in the nuclei of villous cytotrophoblasts of the human placenta. In this study, we examined the effect of fetal gender on the cytotrophoblast cell activity in human term placenta, with special regard to maternal serum and cord blood hCG levels.

Should advanced age alone be considered a contraindication to systemic lymphadenectomy in gynecologic oncologic patients? A university hospital experience in Turkey.

In this case-control study, we aimed at analyzing the effect of pelvic and paraaortic lymphadenectomy on intraoperative and postoperative morbidity and mortality rates in a series of elderly patients (age >/= 65 years) with gynecologic malignancies. We examined preexisting medical conditions, surgical data, intraoperative and postoperative morbidity and mortality in 37 patients aged 65 years or older with endometrial and ovarian carcinoma who underwent pelvic and paraaortic lymphadenectomy. Control group consisted of patients between 60 and 64 years with similar malignancies.

Comparison of in vitro tensile bond strengths of luting cements to metallic and tooth-colored posts.

The aim of this study was to compare the tensile bond strength of tooth-colored ceramic and carbon-fiber post materials as well as titanium and stainless steel post materials luted with three different kinds of luting cements. Disks of alloy post materials were polished with 600-grit SiC paper, air abraded, and ultrasonically cleaned. Ceramic surfaces were pretreated with hydrofluoric acid and silanized.

Temporomandibular disorders in Turkish children with mixed and primary dentition: prevalence of signs and symptoms.

The prevalence of signs and symptoms related to TM (temporomandibular) disorders was examined in 40 children with primary dentition and in 40 children with mixed dentition. The purpose of this study was to evaluate the relationship between dentition and TM disorders in the examined population. Maximum mouth opening was also evaluated.

Mayer-Rokitansky-Küster-Hauser syndrome associated with pulmonary stenosis.

Two siblings with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome associated with pulmonary valvular stenosis are reported. Although the syndrome is well documented, the genetic background and familial occurrence is not known and the association with cardiac anomalies has not previously been reported. This report is the first report which describes the combination of cardiac anomaly with MRKH syndrome.

[Assessment of atrial pathologies in children using transesophageal echocardiography].

Objective: Transesophageal echocardiography (TEE) is indicated for suspected atrial septal pathology and for monitoring of interventional procedures such as an atrial septal defect (ASD) closure during cardiac catheterization. Transesophageal echocardiography also helps to demonstrate postoperative complications and residual defects of complex congenital cardiac anomalies.

Methods: Transesophageal echocardiography was performed in 112 pediatric patients with or suspected atrial pathology at our institution between 1999-2002, using the standard techniques.

Absent pulmonary valve syndrome diagnosed by fetal echocardiography.

Prenatal echocardiographic diagnosis of heart defects is important because it permits counseling of the parents with regard to prognosis and treatment options and prepares the medical team for the treatment postnatally. A male infant with absent pulmonary valve syndrome diagnosed prenatally at 22 weeks' gestation is reported. This congenital anomaly is characterized by absent or rudimentary pulmonary valve cusps, conoventricular septal defect, and massive dilatation of the pulmonary arteries.

Thyroid hemiagenesis associated with Graves' disease and Graves' ophthalmopathy: case report.

Failure of embryologic development of a lobe of the thyroid gland is a rare anomaly. Usually, this condition is diagnosed when there are some other pathologic conditions in the gland and is often found when a patient presents with a thyroid nodule, which in reality is compensatory hypertrophy of the side that is present, therefore appearing as a nodule. A variety of pathological conditions occur in the remaining thyroid tissue in association with this rare anomaly such as adenoma, carcinoma, subacute thyroiditis, colloid nodule, Graves' disease, simple goiter, and Hashimoto thyroiditis.

5-Pyrimidylboronic acid and 2-methoxy-5-pyrimidylboronic acid: new heteroarylpyrimidine derivatives via Suzuki cross-coupling reactions.

5-Pyrimidylboronic acid and 2-methoxy-5-pyrimidylboronic acid 4 have been synthesised by lithium-halogen exchange reactions on 5-bromopyrimidine and 2-methoxy-5-bromopyrimidine, respectively, followed by reaction with triisopropylborate. Suzuki cross-coupling reactions of 2 and 4 with heteroaryl halides [Na(2)CO(3), Pd(PPh(3))(2)Cl(2), 1,4-dioxane, 95 degrees C] yield heteroarylpyrimidines (heteroaryl = thienyl, quinolyl and pyrimidyl). Two-fold reaction of 2 with 4,6-dichloropyrimidine 12 gave 4,6-bis(5-pyrimidyl)pyrimidine 8(56% yield).

Left atrial appendage aneurysm presenting with recurrent embolic strokes.

A case of left atrial appendage aneurysm is described in a 40-year-old man, who presented with recurrent embolic strokes and was asymptomatic until the last 6 months. Chest X-ray revealed a slightly prominent upper left heart border. The diagnosis was made by transthoracic two-dimensional echocardiography and confirmed by transesophageal echocardiography, magnetic resonance imaging and also by surgery.