[The historical aspects of development of concept of endometriosis: publications review].

The endometriosis is a chronic gynecological disease, etiology and pathogenesis of which are not fully clear to science. Its consequences are hardest burden for health care, society and every female patient and her family. The presented review tries to answer in historical aspect the question of interest to all scientists - why endometriosis, known to science for more than 300 years, still remains "disease of riddles and assumptions"? The search of publications was implemented in such databases as Web of Science, eLibrary, Scopus, PubMed/MEDLINE.

Hybrid Revascularization for Aorto-Iliac Occlusive Disease with Common Femoral Artery Involvement: Early Outcomes of a Single Centre.

Objective: To study the early outcomes of aorto-iliac occlusive disease with common femoral artery involvement by hybrid methods of revascularization - iliac stenting with femoral endarterectomy. We report the initial experiences of a single centre and discuss issues that arose.

Methods: Ninety-eight critical limb ischaemia (CLI) patients with aorto-iliac occlusive lesions TASC-II C and D were treated using HR between January 2017 and September 2020 in the Ivano-Frankivsk Regional Clinical Hospital.

[APPLICATION OF LARGE SUBCUTANEOUS VEIN AS MATERIAL FOR DISTAL SHUNTING IN CRITICAL ISCHEMIA OF THE LOWER EXTREMITY TISSUES].

While performing autologous reconstruction of distal arteries in 24 patients in chronic critical ischemia of the lower extremity tissues the method of a large subcutaneous vein mobilization, using a ring-like desobliterator,was applied. This have permitted to reduce the procedure traumaticity, comparing with a standard method. Additional application of pharmacological vasodilatation of venous transplant have permitted to avoid the risk, connected with impact of hydraulic vasodilatation on the venous wall functional state.

[The prediction of the membrane-damaging action of chemical substances in experiments on bacteria].

Comparative study of the cytoplasmic membrane sensitivity in procaryotic cells (E. coli) and eucaryotic cells (rat red blood cells) to bis-quaternary ammonea compounds and diatomic aliphatic alcohols was carried out. Comparative study of the membrane permeability demonstrated, that E.

[Adaptation of pathogens of purulent infections to surface-active antiseptics].

A comparative study was carried out of adaptative capacities of microorganisms to antiseptic agents from the group of cationic surface-active substances (SAS) and antibiotics. It was established that antiseptic agents from SAS group may induce the appearance of resistant to them populations of microorganisms. The resistance acquired to one of the surface-active antiseptics spreads to other agents of this group.

[Effect of corticotropin on the dehydrogenase activity of cells and tissues].

The authors studied the effect of native ACTH on dehydrogenase activity of isolated strips of rat diaphragm and suspension of E. coli cells, serotype O III:B4, grown on beef extract agar in a medium with different dehydrogenation substrates. ACTH activated dehydrogenase of rat diaphragm in a medium containing pyruvate, alpha-ketoglutarate, malate, beta-hydroxybutyrate, D-aspartic acid and did not alter it in a medium containing succinate.

[The effect of corticotropin and hydrocortisone on the dehydration of Krebs cycle substrates in E. coli cells].

Corticotropin and hydrocortisone were studied for their effect on dehydrogenase activity of microbial E. coli cells in the medium with the tricarboxylic acid cycle substrates, glucose and beta-oxybutyric acid. Corticotropin, as distinct from hydrocortisone, is shown to increase the dehydrogenase activity of microbial cells when pyruvate, isocitrate, oxaloacetate, alpha-ketoglutarate, succinate, furmarate, glucose and beta-oxybutyrate are used as substrates.

[Joint action of ethonium and antibiotics on gram-positive and gram-negative microorganisms].

The inhibitory effect of antibiotics and their combinations with ethonium was studied in vitro with 10 strains of Staph. aureus and 10 strains of E. coli, Sh.

[Relationship between cationic structure and the biological activity of cationic surface-active substances].

The paper concerns the toxicity and antimicrobial activity of the derivatives of ethylene-, hexamethylenediamine, piperidine and guanidine containing an alkyl group with 10-12 carbon atoms adjacent to nitrogen ones. Alkyl derivatives of hexamethylenediamine and guanidine exhibit less toxicity compared to those of piperidine and ethylenediamine. Antimicrobial activity of the compounds is cation is cation structure-dependent and is most pronounced in guanidine and piperidine derivatives having a wide spectrum of antimicrobial action.