Publications by authors named "Gudrun J Gudlaugsdottir"
Am J Hum Genet
March 2002
Article Synopsis
- Stroke is a complex disease with various subtypes and multiple secondary risk factors like hypertension and diabetes, which have their own genetic and environmental influences.
- Researchers conducted a genomewide search for genes that might increase susceptibility to common stroke forms by analyzing data from stroke patients in Iceland and a genealogy database, identifying 476 patients within 179 extended families.
- A significant discovery was made on chromosome 5q12, with a high LOD score indicating strong evidence for a genetic link to stroke; this region, named "STRK1," is novel and not previously associated with known stroke susceptibility loci.
