A rare case of spinal involvement in hereditary hemorrhagic telangiectasia.

Introduction: Here, we describe a rare case of a spinal arteriovenous fistula in a patient with known hereditary hemorrhagic telangiectasia (HHT) and spontaneous intraspinal hemorrhage. Furthermore, we provide a brief review of the literature on the formation of spinal arteriovenous malformations (AVM) in relation to this disease.

Case Presentation: The case involves a 54-year-old male with known HHT.

Cryoneurolysis versus radiofrequency ablation outcome on pain experience in chronic low back pain (COPE): a single-blinded randomised controlled trial.

Objective: A comparison of cryoneurolysis or radio frequency (RF) with placebo in patients with facetogenic chronic low back pain (LBP) for patient global impression of change (PGIC), pain intensity, function and quality of life, with 1-year follow-up.

Design: Single-centre, single-blinded placebo-controlled randomised controlled trial.

Setting: Single-centre study.

Combined achondroplasia and short stature homeobox-containing (SHOX) gene deletion in a Danish infant.

Short stature or shortening of the limbs can be the result of a variety of genetic variants. Achondroplasia is the most common cause of disproportionate short stature and is caused by pathogenic variants in the fibroblast growth factor receptor 3 gene (FGFR3). Short stature homeobox (SHOX) deficiency is caused by loss or defects of the SHOX gene or its enhancer region.

Allocating operating room capacity to non-elective neurosurgical patients improves access and safety for elective patients at Aarhus University Hospital.

Introduction: This study addresses surgical scheduling within the Department of Neurosurgery at Aarhus University Hospital (AUH). The department provides neurosurgical care to a population of 1.3 million in central Denmark, and has treatment obligations for specific neurosurgical diseases for the entire country, which has a population of 5.

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Intraoperative neuromonitoring (IONM) allows for a perioperative evaluation of the functional integrity of the spinal cord and nerve roots during intradural neurosurgery. This review examines established techniques as somatosensory evoked potentials and motor evoked potentials, as well as electromyography which all provide real-time feedback for the surgical team. IONM represents a valuable tool which can identify emerging neurological complications, and thus can be utilised to reduce the incidence of postoperative neurological deficits by timely interventions.

Outcome and negative events in thoracic disc herniation surgery: a Danish registry study.

Background: Thoracic disc herniation (TDH) is a surgically demanding entity. Various surgical approaches have been developed and advanced in an attempt to achieve sufficient outcomes and reduce consecutive complication rates. Still, controversy exists regarding selecting the best surgical approach.

The incidence and effect of tethered cord release for tethered cord syndrome in patients with myelomeningocele: a population-based study.

Objective: The goal of this study was to establish an incidence and assess the effect of tethered cord release for tethered cord syndrome in patients with myelomeningocele.

Methods: The study population was based on the Western Denmark Myelomeningocele Database, which contains all patients born with myelomeningocele in western Denmark since 1970. The study population was cross-referenced in 2015 with a database for surgical procedures containing all surgical procedures performed in the central Denmark region since 1996.

Characteristics and outcomes in patients with primary intraspinal tumours.

Introduction: We report a retrospective cohort study aimed at presenting data on incidence, patient char-ac-teristics, tumour type, level of pathology, clinical status before and after surgery and complications in patients with surgically treated primary intraspinal tumours (PIST) in Western Denmark.

Methods: Population-based data were retrieved from hospital files from 1 January 2010 to 31 December 2015.

Results: In total, 78 males and 88 females with PIST were included in the study.

Novel variant causes a severe form of metatropic dysplasia.

We present a girl born with a frontal bossing, short neck, bell-shaped thorax, short limbs with prominent joints, and a tail-like coccygeal appendage. Genetic screening of identified a novel de novo heterozygous missense variant. We believe the variant causes the severe form of metatropic dysplasia in this patient.

Repair of myelomeningocele using autologous amnion graft and local flaps. A report of two cases.

We describe two cases where autologous amnion grafts were used to cover the neurosurgical repair of myelomeningocele (MMC) and the reconstructive flaps used for the skin defects. MMC is a severe fetal defect that evolves during embryonic development as a result of the neural tubes failure to close. In postnatal MMC closure, early timing of surgical repair is essential.

Dural repair using porcine ADM: two cases and a literature review.

The use of acellular dermal matrices (ADM) for dural repair is very scantily described in the literature. We report two cases of dural repair using porcine ADM and a literature review. ADM and especially Strattice pliable may be a useful alternative to other dural substitutes.

Electroencephalography as a clinical tool for diagnosing and monitoring attention deficit hyperactivity disorder: a cross-sectional study.

Objectives: The aim of this study was to develop and test, for the first time, a multivariate diagnostic classifier of attention deficit hyperactivity disorder (ADHD) based on EEG coherence measures and chronological age.

Setting: The participants were recruited in two specialised centres and three schools in Reykjavik.

Participants: The data are from a large cross-sectional cohort of 310 patients with ADHD and 351 controls, covering an age range from 5.

Managing school atmosphere through large groups: a five-session trial.

Unlabelled: This paper describes an attempt to influence school atmosphere through a large group in an elementary school. Another goal was to increase the students' feeling of responsibility for the school environment through training in democratic processes. A third goal was to explore how applicable the group dynamics of the large group are for 1st to 6th graders.

Psychological distress and professional help-seeking: a prospective national study.

The study focuses on use of different healthcare providers in connection with elevated levels of psychological distress. The study used a prospective design based on two waves of a national health survey. Participants were Icelandic citizens, age 18-75, randomly drawn from the National Register (N = 1592).

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.

We conducted a genome-wide association study for primary open-angle glaucoma (POAG) in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a common sequence variant at 7q31 (rs4236601[A], odds ratio (OR) = 1.36, P = 5.

Group differences in outpatient help-seeking for psychological distress: results from a national prospective study of Icelanders.

Aims: This study focused on group differences in health care use for psychological distress. Specifically, the study examined if some subgroups and kinds of distress predicted use of particular providers.

Methods: The study uses data from a repeated national postal health survey of a random sample of Icelanders aged 18-75.

[Rheumatoid arthritis with atlanto-axial subluxation. Pre-and postoperative symptoms, radiological findings and operative complications].

Introduction: The aim of the study was to study pre- and postoperative symptoms, radiological findings and operative complications in rheumatoid arthritis (RA) patients, operated in the atlantoaxial joint.

Materials And Methods: A retrospective study of 31 RA patients (24 women, seven men) operated for anterior atlantoaxial subluxation (aAAS) at the Neurosurgical Department, Aarhus University Hospital, in the period of 1993-2003. Information was obtained retrospectively from the patients charge.

Can the prevalence of open-angle glaucoma be estimated from a retrospective clinical material? A study on the west coast of Iceland.

Purpose: To explore the possibility of estimating the prevalence of open-angle glaucoma (OAG) on the west coast of Iceland using a clinical retrospective material, and to compare that estimate with the results from a recent prospective Icelandic study.

Methods: The compulsory ophthalmological examination for the prescription of eye glasses in combination with information obtained from Statistics Iceland were used to establish the prevalence of glaucoma in Akranes and to estimate the minimum prevalence for the greater west coast area. A recent prospective study from Iceland was used as reference.

Staphylococcus aureus meningitis: experience with cefuroxime treatment during a 16 year period in a Danish region.

Staphylococcus aureus is a rare cause of bacterial meningitis and there is no consensus on antibiotic treatment. Nafcillin is a common choice in countries where it is approved and marketed. High-dose cefuroxime has been the systemic treatment used in the study region, and a retrospective record review was conducted to determine its clinical efficacy.