[Identification of congenital adrenal hyperplasia by measurement of blood-spot 17-hydroxyprogesterone].

Unlabelled: Identification of congenital adrenal hyperplasia by measurement of blood-spot 17-hydroxyprogesterone.

Introduction: 21-hydroxylase deficiency (21-OHD) is the most common cause of congenital adrenal hyperplasia (CAH). The simplest way to diagnose the disease is the measurement of 17-hydroxyprogesterone level in the serum.

Twenty years experience in rapid identification of congenital adrenal hyperplasia in Hungary.

Unlabelled: The aim of this study was to assess the effectivity of the identification of patients with congenital adrenal hyperplasia (CAH) in Hungary in the absence of systematic neonatal screening and to estimate the incidence. Dried blood-spot samples of patients clinically suspected at any age to have CAH were collected between 1978 and 1998 throughout the whole country. 17-Hydroxyprogesterone (17-OHP) was measured by radioimmunoassay.