Publications by authors named "Gudny Eirksdottir"
Article Synopsis
- Nonalcoholic fatty liver disease (NAFLD) is widespread, partly genetic, and currently lacks effective treatment options.
- A genome-wide association study (GWAS) identified several genetic variants linked to NAFLD, focusing on genes related to metabolism and liver function.
- Genetic risk factors can help classify NAFLD into subtypes and significantly increase the risk of severe liver complications, potentially aiding in the development of targeted therapies.
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and is highly correlated with metabolic disease. NAFLD results from environmental exposures acting on a susceptible polygenic background. This study performed the largest multiethnic investigation of exonic variation associated with NAFLD and correlated metabolic traits and diseases.
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