Aim: The aim of this study is, to evaluate and compare the diversity of genotypes with respect to caries activity among normal children and intellectually disabled children, which would enable the clinician to plan better strategies for early caries detection, management and prevention.
Materials And Methods: Genotyping of was done by collecting the saliva samples from 40 caries active children (20 normal and 20 children associated with intellectual disability by Rapid amplified polymorphic DNA analysis using three arbitrarily primers (P1, P2, P3). Rapid amplified polymorphic DNA (RAPD) is preferred because of its reliability, reproducibility in generating genetic fingerprints of isolates.