Publications by authors named "Gudesh Kumar"
Article Synopsis
- Multidrug-resistant tuberculosis (MDR-TB) is a form of TB that does not respond to at least two key medications, isoniazid and rifampicin, and the study focused on evaluating how well an all-oral longer treatment regimen works for these patients.
- Conducted at IGIMS, Patna from October 2020 to March 2022, the research tracked culture conversion in MDR-TB patients using sputum samples analyzed over a six-month period after starting treatment.
- Results showed that after two months, 95.1% of patients had positive sputum cultures, which dramatically improved to 85.2% negative cultures after six months, indicating the effectiveness of the all-oral regimen,
Introduction: Individuals with human immunodeficiency virus (HIV) infection have an increased likelihood of developing tuberculosis (TB). The primary objective of this study was to compare the diagnostic accuracy of microscopy, culture, and the Xpert /Rifampicin (MTB/RIF) assay in the diagnosis of pulmonary TB in sputum samples of HIV-infected patients. The secondary objectives were to evaluate the sensitivity and specificity of these three methods along with a comparison of diagnostic approaches for detecting drug-resistant strains.
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