[The diagnosis of the severity of blood loss and general principles for the combined treatment of hemorrhage in relation to its severity].

The method of the blood loss severity estimation, basing on electrochemically registered globular volume deficiency (ECRGVD) was proposed. Classification of an acute blood loss severity accordingly to ECRGVD value was elaborated, general principles of complex treatment of hemorrhage were proposed.

[Postradiation structural changes in the thymocyte and lymphocyte plasma membranes in the fractional irradiation of rats].

On days 1 and 4 after fractionated irradiation of rats with dose of 0.75 Gy changes in thymocyte and lymphocyte plasma membrane structures were studied. Structural parameters of fluorescence probe auramin binding, viscosity of free lipids and lipids bound with integral proteins as well as structural changes of membrane protein structure were determined.

[A scientific knowledge analysis of the problem of the biomedical sequelae of the accident at the Chernobyl Atomic Electric Power Station].

The authors carried out a scientific-research analysis of publication on the problem of medico-biological sequels of the Chernobyl Atomic Station. Systematization of 282 native and 45 foreign publications are presented as information models emphasizing the main trends of research, especially changes in the nervous system as well as in related systems of the body. Further detailed studies of the Chernobyl disaster sequels are important.

[The determination of the volume of circulating plasma using the indicator T-1824].

A method for measuring circulating plasma volume (CPV) by diluting T-1824 indicator is described, making allowance for the exponential pattern of labeled serum albumin elimination from the vascular bed. The method consists in double collection of blood samples after intravenous injection of the indicator, computation of the constant of its extravasation rate, and extrapolation to the zero time. Analysis of the results obtained by this method and CPV values derived from the hematocrit and circulating blood volume--(CBV) estimated with the help of Albert table (1971), as well as with CPV value derived from the hematocrit and CBV measured by impedance method in 22 patients with slight uncomplicated ventral and diaphragmal hernias has demonstrated high linear correlation coefficients, +0.

[Protein synthesis and content of free amino acids in rat organs in experimental peritonitis].

Experiments performed on rats shown that in peritonitis the mass of the animal's organs and C14-amino acid incorporation into tissue proteins is reduced. Free amino acid content in tissues and serum is increased. Decreased incorporation of C14-amino acid into hepatic proteins antecedes the increase of free amino acid content in this organ.

[Interrelation of the intracellular oxidation-reduction processes and the organic water balance in experimental peritonitis in rats].

Dissociation of oxidative phosphorylation and the lowering of the respiratory control during oxidation of succinate, alpha-ketoglutarate and pyruvate by hepatocyte mitochondria were observed in rats with experimental fecal peritonitis. The initial increase in the oxidation rate of the substrates enumerated is replaced by inhibition, whose degree is maximal as regards alpha-ketoglutarate, being less manifest as regards succinate. In the absence of the manifestations of the total dehydration, the increased water content in liver, skeletal muscle and renal tissues is coupled with relatively high values of the ADP/O and is in a good agreement with the lowering of the respiratory control during alpha-ketoglutarate oxidation.

[Energy allowance for antibody formation in rabbits immunized with cholera vaccine and by exposure to tetracyclines].

Oxidative phosphorylation and succinate dehydrogenase activity in liver mitochondria, as well as activity of glucoso-6-phosphate dehydrogenase in liver homogenates were studied on 126 rabbits immunized with cholera vaccine and exposed to tetracycline or doxycycline (vibramycin). It was found that tetracycline and especially doxycycline inhibited the bioenergy processes in both intact and immunized animals. The inhibitory effect of doxycycline was most pronounced in the immunized rabbits.