Angiogenesis-related ultrastructural changes to capillaries in human skeletal muscle in response to endurance exercise.

The ultrastructure of capillaries in skeletal muscle was morphometrically assessed in vastus lateralis muscle (VL) biopsies taken before and after exercise from 22 participants of two training studies. In study 1 (8 wk of ergometer training), light microscopy revealed capillary-fiber (C/F) ratio (+27%) and capillary density (+16%) to be higher (P ≤ 0.05) in postexercise biopsies than in preexercise biopsies from all 10 participants.

Selective photothermolysis to target sebaceous glands: theoretical estimation of parameters and preliminary results using a free electron laser.

Background And Objectives: The success of permanent laser hair removal suggests that selective photothermolysis (SP) of sebaceous glands, another part of hair follicles, may also have merit. About 30% of sebum consists of fats with copious CH(2) bond content. SP was studied in vitro, using free electron laser (FEL) pulses at an infrared CH(2) vibrational absorption wavelength band.

Selective photothermolysis of lipid-rich tissues: a free electron laser study.

Background And Objectives: In theory, infrared vibrational bands could be used for selective photothermolysis of lipid-rich tissues such as fat, sebaceous glands, or atherosclerotic plaques.

Study Design/materials And Methods: Absorption spectra of human fat were measured, identifying promising bands near 1,210 and 1,720 nm. Photothermal excitation of porcine fat and dermis were measured with a 3.

Free-electron-laser oscillator with a linear taper.

We present experiments and simulations showing the behavior of a free-electron laser (FEL) with both positive and negative linear tapers along the wiggler. We show the power desynchronism curve widths, efficiency, exhaust electron energy spread, and wavelength dependence as a function of taper for 3- and 6-microm optical wavelengths and for resonators with 10% and 2% loss/pass. Simulations of the experiments, using a multimode analysis, are seen to be in general agreement with the experimental results, carried out at the IR Demo FEL at Thomas Jefferson National Accelerator Facility.

Second harmonic FEL oscillation.

We have produced and measured for the first time second harmonic oscillation in the infrared region by a free electron laser. Although such lasing is ideally forbidden, since the gain of a plane wave is zero on axis for an electron beam perfectly aligned with a wiggler, a transverse mode antisymmetry allows sufficient gain in this experiment for lasing to occur. We lased at pulse rates up to 74.

Sustained kilowatt lasing in a free-electron laser with same-cell energy recovery.

Jefferson Laboratory's kW-level infrared free-electron laser utilizes a superconducting accelerator that recovers about 75% of the electron-beam power. In achieving first lasing, the accelerator operated "straight ahead" to deliver 38-MeV, 1.1-mA cw current for lasing near 5 &mgr;m.