Publications by authors named "Guanzeng Li"

Article Synopsis
  • PCSK9 inhibitors like Evolocumab can significantly lower LDL cholesterol levels in patients already on statins, but their effect on symptomatic intracranial atherosclerosis has not been studied.
  • The study aims to compare the effects of combining Evolocumab with statins versus using statins alone on reducing intracranial plaque burden in patients with recent strokes or transient ischemic attacks.
  • With 1,000 participants and advanced imaging techniques, the trial will assess important outcomes over a 24-week period to determine whether the combination therapy is more effective and to gather safety data.
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To date, there has been no consensus regarding the benefits of percutaneous transluminal angioplasty and stenting (PTAS) vs. those of standardized medical treatment (SMT) for patients with symptomatic intracranial vertebrobasilar stenosis (IVBS). The purpose of this retrospective study was to compare the effects of PTAS or SMT on symptomatic IVBS in a real-world Chinese population.

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Alzheimer's disease (AD) is a progressive disease and the predominant cause of dementia. Common symptoms include short-term memory loss, and confusion with time and place. Individuals with AD depend on their caregivers for assistance, and may pose a burden to them.

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Psychological problems are common among end-stage renal disease patients undergoing dialysis. We aim to evaluate whether high-dose vitamin D3 (VD3) supplementation has beneficial effects on depressive symptoms in dialysis patients. This prospective, randomized, and double-blind trial includes 746 dialysis patients with depression treated in 3 hospitals in Southeast China.

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Accumulating evidence shows that microRNA (miRNA) is frequently associated with multiple kinds of human cancers, including colorectal cancer (CRC). Previous studies have shown that miR-592 play critical roles in cancer cell biological processes. However, the function of miR-592 in CRC remains largely unknown.

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