Turbulent flow field in maglev centrifugal blood pumps of CH-VAD and HeartMate III: secondary flow and its effects on pump performance.

Secondary flow path is one of the crucial aspects during the design of centrifugal blood pumps. Small clearance size increases stress level and blood damage, while large clearance size can improve blood washout and reduce stress level. Nonetheless, large clearance also leads to strong secondary flows, causing further blood damage.

Resistance valves in circulatory loops have a significant impact on evaluation of blood damage caused by blood pumps: a computational study.

Hemolysis and its complications are major concerns during the clinical application of blood pumps. circulatory testing loops have been employed as the key procedure to evaluate the hemolytic and thrombogenic performance of blood pumps during the development phase and before preclinical animal studies. Except for the blood damage induced by the pump under test, blood damage induced by loop components such as the resistance valve may affect the accuracy, reproducibility, and intercomparability of test results.

A hemodynamic analysis of fenestrated physician-modified endograft repair for complicated aortic dissections involving the visceral arteries.

Objective: The aim of this study is to perform patient-specific hemodynamic simulations of the patients with complicated aortic dissection underwent Physician-modified endograft (PMEG) and evaluate the treatment outcome.

Method: 12 patient-specific models were reconstructed from computed tomography angiography (CTA) data of 6 patients with complicated aortic dissection before and after the PMEG. Hemodynamic simulations were conducted with the same time-varying volumetric flow rate extracted from the literature and 3-element Windkessel model (3 EWM) boundary conditions were applied at the aortic outlet.