Publications by authors named "Guansheng Zeng"
Purpose: To investigate the differential clinical significance of fractional concentration of exhaled nitric oxide measured at a flow rate of 200 mL/s (FENO) and concentration of nitric oxide in alveolar (CANO) in asthma, chronic obstructive pulmonary disease (COPD) or asthma-COPD Overlap (ACO).
Methods: A total of 178 patients were included, with 82 patients in asthma group, 47 patients in COPD group and 49 patients in ACO group. Data for demographic data, spirometry and exhaled nitric oxide were collected for comparative analysis, correlation analysis and discriminant canonical analysis.
Article Synopsis
- Asthma can cause a long-lasting cough, and scientists studied a special marker called CANO in the lungs to learn more about it.
- They included 155 patients with subacute cough, 25 of whom had asthma, and checked different lung function tests and measurements of CANO and another marker called FeNO.
- The study found that both asthmatic and non-asthmatic patients had similar CANO levels, but CANO was better at showing lung health compared to FeNO, especially in people with asthma.
Article Synopsis
- - The study aimed to assess how effective fractional exhaled nitric oxide (FeNO) and maximum mid-expiratory flow (MMEF) are at distinguishing cough variant asthma (CVA) from chronic cough in patients, regardless of whether they have allergic rhinitis or not.
- - In a sample of 328 patients, researchers found that optimal cutoff values for FeNO and MMEF to differentiate CVA from chronic cough were 24.5 ppb and 66.2%, respectively, with better accuracy when both measures were combined.
- - Results suggested that FeNO and MMEF are valuable in ruling out CVA, and the diagnostic accuracy for FeNO is higher in patients with allergic rhinitis compared to those without
The relationship between steps of 6MWT and COPD severity: a cross-sectional study.
Int J Chron Obstruct Pulmon Dis
July 2019
Background And Objective: The distance of 6-minute walk test (D6MWT) has been widely used in the assessment of functional status in patients with COPD, while very little attention has been paid to the role of steps of 6-minute walk test (S6MWT). The purpose of this study was to investigate the relationship between S6MWT and other physiologic parameters of COPD.
Patients And Methods: Seventy patients with stable COPD were enrolled consecutively in this cross-sectional study.