Publications by authors named "Guanjin Yin"
It remains unclear whether carbon content in airway macrophages (AM) can predict personal short-term exposure to fine particulate matter (PM) air pollution and its respiratory health effects. We aimed to evaluate the pathway from personal PM exposure to adverse respiratory outcomes through AM carbon content. We designed a longitudinal panel study with 3 scheduled follow-ups among 113 non-smoking patients of chronic obstructive pulmonary disease in Shanghai, China, from April 2017 to January 2019.
View Article and Find Full Text PDFBackground: Previous studies have suggested acute effects of ambient fine particulate matter (PM) air pollution on respiratory health among children, but evidence for PM constituents and respiratory health were still limited.
Objectives: To investigate associations of short-term exposure to PM and its constituents with airway inflammation, lung function, and airway microbiota in children.
Methods: We conducted a longitudinal panel study with 3 repeated health measurements among 62 children in Shanghai, China from November 2018 to June 2019.
Article Synopsis
- Particulate matter (PM), particularly ultrafine particles (UFPs), significantly impacts children's respiratory health, but studies on UFPs are limited.
- A panel study conducted in Shanghai involved 65 pupils, measuring UFP concentrations and their health effects through saliva, microflora, exhaled nitric oxide, and lung function over several months.
- Results showed that higher UFP exposure led to increased inflammation markers, reduced lung function, and lower diversity in oral bacteria, indicating detrimental respiratory impacts on children.
Article Synopsis
- The study investigates the impact of dietary fish-oil supplementation on oxidative stress caused by outdoor air pollution, specifically the combined levels of nitrogen dioxide and ozone.
- The research involved 65 young adults in Shanghai, who were randomly assigned to either a fish-oil or placebo group, with physical examinations and biomarker measurements taken throughout the trial.
- Results showed that participants taking fish oil experienced less oxidative stress and higher antioxidant activity compared to those on the placebo, indicating potential protective effects against air pollution.
Article Synopsis
- The study explored whether omega-3 fatty acid (fish oil) supplementation can protect cardiovascular health in areas with high fine particulate matter (PM) pollution in China.
- Conducted among 65 healthy college students in Shanghai, the trial was randomized, double-blinded, and placebo-controlled, with participants taking 2.5 g/day of fish oil over four rounds of health examinations.
- Results indicated that the fish-oil group maintained more stable biomarker levels in response to PM exposure, showcasing potential short-term cardiovascular benefits from the supplementation.