Predicting the early therapeutic response to hepatic artery infusion chemotherapy in patients with unresectable HCC using a contrast-enhanced computed tomography-based habitat radiomics model: a multi-center retrospective study.

Objective: Predicting the therapeutic response before initiation of hepatic artery infusion chemotherapy (HAIC) with fluorouracil, leucovorin, and oxaliplatin (FOLFOX) remains challenging for patients with unresectable hepatocellular carcinoma (HCC). Herein, we investigated the potential of a contrast-enhanced CT-based habitat radiomics model as a novel approach for predicting the early therapeutic response to HAIC-FOLFOX in patients with unresectable HCC.

Methods: A total of 148 patients with unresectable HCC who received HAIC-FOLFOX combined with targeted therapy or immunotherapy at three tertiary care medical centers were enrolled retrospectively.

The Critical Role of Ca in Improving the Transparency and Strength of High-Filler-Content Nanocellulose/Montmorillonite Nanocomposite Films.

Strong and transparent nanocellulose/montmorillonite (MMT) nanocomposite films with high filler content (≥50 wt %) are emerging as versatile materials for advanced applications due to their excellent optical, barrier, mechanical, and thermal properties, and environmental friendliness. Nonetheless, these films undergo a notable decline in optical and mechanical properties at high MMT loadings. This study first demonstrates that calcium-ion-induced tactoids are the key factor causing disordered structures in nanocomposite films, leading to the degradation of optical and mechanical properties.

Strong Yet Tough Transparent Paper with Superb Foldability.

Transparent paper manufactured from wood fibers is emerging as a promising, cost-effective, and carbon-neutral alternatives to plastics. However, fully exploring their mechanical properties is one of the most pressing challenges. In this work, a strong yet tough transparent paper with superior folding endurance is prepared by rationally altering the native fiber structure.

The anticancer effects of FS48 from salivary glands of on NCI-H460 cells its blockage of voltage-gated K channels.

Voltage-gated K (K) channels play a role in the cellular processes of various cancer cells, including lung cancer cells. We previously identified and reported a salivary protein from the , FS48, which exhibited inhibitory activity against K1.1-1.

Mechanically stable core-shell cellulose nanofibril/sodium alginate hydrogel beads with superior cu(II) removal capacity.

Nanocellulose hydrogels are promising sustainable biosorbents for removing heavy metal ions for wastewater treatment. However, the nanocellulose hydrogels reported thus far typically suffer from inferior adsorption performance and/or poor mechanical stability, thus limiting their industrial applications. Achieving the goals of mechanical stability and high removal capability remains a crucial technical challenge, which may be addressed, as presented in this study, by developing novel core-shell carboxymethylated cellulose nanofibril (CMCNF)/sodium alginate (SA) hydrogel beads (CAbs).

Cassava () Slow Anion Channel () Gene Overexpression Enhances Nitrogen Assimilation, Growth, and Yield in Rice.

Nitrogen is one of the most important nutrient elements required for plant growth and development, which is also immensely related to the efficient use of nitrogen by crop plants. Therefore, plants evolved sophisticated mechanisms and anion channels to extract inorganic nitrogen (nitrate) from the soil or nutrient solutions, assimilate, and recycle the organic nitrogen. Hence, developing crop plants with a greater capability of using nitrogen efficiently is the fundamental research objective for attaining better agricultural productivity and environmental sustainability.

PIF4 Promotes Expression of to Enhance Basal Thermotolerance in .

Heat stress (HS) seriously restricts the growth and development of plants. When plants are exposed to extreme high temperature, the heat stress response (HSR) is activated to enable plants to survive. Sessile plants have evolved multiple strategies to sense and cope with HS.

MALT1 in asthma children: A potential biomarker for monitoring exacerbation risk and Th1/Th2 imbalance-mediated inflammation.

Background: Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) participates in the immune-related allergic response and inflammation flare, while its clinical role in asthma children is still unknown. Herein, this study aimed to investigate MALT1 expression, and its correlation with exacerbation risk, T helper (Th)1, Th2 cells (and their secreted cytokines), as well as inflammatory cytokines in asthma children.

Methods: Sixty children with asthma exacerbation and 60 children with remission asthma were enrolled in this study; then their blood MALT1, Th1, Th2 cells, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interferon-gamma (IFN-γ), and interleukin-4 (IL-4) were detected.

Catalase () Gene Family in Wheat ( L.): Evolution, Expression Pattern and Function Analysis.

Catalases () are present in almost all living organisms and play important roles in plant development and response to various stresses. However, there is relatively little information on genes in wheat and related species. A few studies on family genes in wheat have been reported.

Favorable combination of foldability and toughness of transparent cellulose nanofibril films by a PET fiber-reinforced strategy.

Transparent cellulose nanofibril (CNF) films have been considered a promising sustainable alternative for nonrenewable and nonbiodegradable petroleum-based plastic films. However, their relatively low toughness and poor folding endurance are two remaining challenges for commercial application. In this work, inspired by fiber-reinforced polymer, a transparent CNF film with favorable combination of toughness and folding endurance is demonstrated by a facile and scalable polyethylene terephthalate (PET) fiber-reinforced strategy.

Approaching Theoretical Haze of Highly Transparent All-Cellulose Composite Films.

A highly transparent cellulose film with a high built-in haze is emerging as a green photonic material for optoelectronics. Unfortunately, attaining its theoretical haze still remains a challenge. Here, we demonstrate an all-cellulose composite film with a 90.

Comparison between the Effects of Acupuncture Relative to Other Controls on Irritable Bowel Syndrome: A Meta-Analysis.

Background: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder with recurrent abdominal pain and altered defecation habits. We here attempted to determine the effect of acupuncture on IBS.

Methods: Randomized controlled trials (RCTs) published in CNKI, VIP, Wanfang, PubMed, Cochrane Library, EMBASE, Web of science, and ClinicalTrials.

Efficient Removal of Cu in Water by Carboxymethylated Cellulose Nanofibrils: Performance and Mechanism.

Simultaneous production and functionalization of cellulose nanofibrils (CNFs) for heavy metal ion removal is an economical and promising solution to expedite their use in water treatment. In this work, carboxymethylated CNFs (CMCNFs) with a carboxylate content up to 2.7 mmol/g are prepared by a combination of carboxymethylation and homogenization, which show diameters of 3.

[Review of the mechanism of essential hypertension treated by acupuncture].

The relevant literature of pathogenesis of essential hypertension (EH) and the clinical efficacy of acupuncture treatment of EH was retrieved from January 1, 1999 to February 28, 2018 in the CNKI and PubMed databases, and aimed to summarize and explore the mechanism of antihypertensive by acupuncture.It has been found that acupuncture exerts antihypertensive effect by coordinating multi-system, multi-target, multi-layer adjustment mechanism, such as acupuncture inhibiting of central and peripheral sympathetic nerve activity, rejusting immune system and expression of inflammatory response factors, regulating the balance of renin-angiotensin-aldosterone system (RAAS), improving vascular structure and function, the anti-oxidative stress and promoting autophagy.

Sirt1/Foxo Axis Plays a Crucial Role in the Mechanisms of Therapeutic Effects of Erzhi Pill in Ovariectomized Rats.

. Erzhi pill (EZP), a traditional Chinese herbal formula, has been widely used to treat postmenopausal osteoporosis (PMOP) in China. However, its molecular mechanisms remain unclear.

A data-driven noise reduction method and its application for the enhancement of stress wave signals.

Ensemble empirical mode decomposition (EEMD) has been recently used to recover a signal from observed noisy data. Typically this is performed by partial reconstruction or thresholding operation. In this paper we describe an efficient noise reduction method.

Thickness measurement of colloidal opal crystal growth by Bragg reflection.

This study investigates a simple method for thickness estimation with single layer accuracy for self-assembling opal crystals prepared by the dip-coating method. The thickness (number of layers) of the opal crystals was estimated by an analysis of the optical reflectance from s-polarization incident light, and then verified with SEM. The opal crystals were considered as periodic dielectric layers and were analyzed with the transfer matrix method.

[Effects of deltamethrin on neurobehavioral development of offspring of intoxicated rats].

Objective: To investigate the effects of deltamethrin on the filial brain nitric oxide synthase (NOS) activity and neurobehavioral development of the exposed lactational rats.

Methods: Pregnant rats were randomizedly divided into the treated group and the control group. The treated group was administered orally with 3.