Publications by authors named "Guangyu Wen"
Background: Astrocytes are the most populous glial cells in the central nervous system (CNS), which can exert detrimental effects through a process of reactive astrogliosis. Our previous study has indicated the potential effect of Calycosin in preventing spinal cord injury (SCI). This study aims to investigate the mechanism by which calycosin regulates the polarization of A1 astrocytes, a neurotoxic subtype of reactive astrocytes, in SCI models.
View Article and Find Full Text PDFThe authentication of Ziziphi Spinosae Semen (ZSS), Ziziphi Mauritianae Semen (ZMS), and Hovenia Acerba Semen (HAS) has become challenging. The chromatic and textural properties of ZSS, ZMS, and HAS are analyzed in this study. Color features were extracted via RGB, CIELAB, and HSI spaces, whereas texture information was analyzed via the gray-level co-occurrence matrix (GLCM) and Law's texture feature analysis.
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- Previous studies showed that Calycosin (CA) helps with spinal cord injury (SCI), and this study investigates its role in promoting axon growth.
- Researchers created an SCI model in rats and a lab model using chondroitin sulfate proteoglycan (CSPG) to examine how CA affects axon regeneration.
- CA treatment enhanced the growth of nerve cells and increased the levels of specific markers associated with axon regeneration, while also regulating the expression of a direct target protein called PTPRS.
Porous gelatin microspheres (GMSs) were constructed to enhance the neuroprotective effects of fibroblast growth factor 10 (FGF10) against spinal cord injury (SCI). The GMSs were prepared using a water‑in‑oil emulsion, followed by cross‑linking, washing and drying. The blank GMSs had a mean particle size of 35 µm, with a coarse and porous surface.
View Article and Find Full Text PDFConversion of carbon dioxide into useful chemicals has attracted great attention. However, the significant bottlenecks facing in the field are the poor conversion efficiency of CO and low selectivity of products. Herein, hierarchical BiOBr hollow microspheres are fabricated by a solvothermal method using ethylene glycol (EG) as solvent in presence of polyvinyl pyrrolidone (PVP).
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