Relationship between uric acid and cerebral amyloid angiopathy.

To explored Relationship between uric acid and cerebral amyloid angiopathy; ZO-1 and RAGE in HBMECs were detected by western blotting, and then, we analyzed ZO-1, occludin, and RAGE mRNA expression levels in different treatment groups using RTPCR. Cell counts and the relative αSMA fluorescence intensity were measured in order to evaluate the protective effect of uric acid against injury to HBVSMCs. Analysis of variance showed that LDH leakage rate was used to verify the uric acid protective effect on the injury induced by Aβ1-40.

Axial birefringence induced focus splitting in lithium niobate.

We report on the experimental observation of "focus splitting" when light is tightly focused into a uniaxial lithium niobate crystal along its optical axis. This effect consists in the focal spot being split into two major sub-peaks along the axial direction. For the microfabrication applications such as three-dimensional photonic crystal fabrication and waveguide writing, this effect is highly undesired since it can lead to the generation of multiple distinct voxels in the vicinity of the focus.

Observation of multiple higher-order stopgaps from three-dimensional chalcogenide glass photonic crystals.

For the first time to our knowledge the observation of near-IR multiple higher-order stopgaps in three-dimensional photonic crystals (PhCs) fabricated using the direct-laser-writing method in thick chalcogenide glass films is reported. The fabrication and etching conditions necessary to realize well-defined structures are presented. The fabricated PhCs exhibit higher-order stopgaps, which are only evident in high-quality structures.

Fabrication of three-dimensional woodpile photonic crystals in a PbSe quantum dot composite material.

Incorporating active media into three-dimensional (3D) photonic crystals (PCs) is a useful step towards exploring the functionalities of PCs. Here we report, for the first time, on the fabrication of 3D woodpile PCs with a commercial PbSe quantum dot (QD) composite material by using the two-photon polymerization technique. The fabricated crystals possess photonic band gaps in the near-infrared wavelength region, which have a suppression rate of ~50% in the stacking direction, measured with an angle-resolved Fourier-transform infrared spectrometer.

Direct optical fabrication of three-dimensional photonic crystals in a high refractive index LiNbO3 crystal.

Direct optical fabrication of 3D photonic crystals in a high refractive index LiNbO3 crystal by using the femtosecond laser-induced microexplosion method is investigated. The focal distortion, caused by the refractive index mismatch-induced spherical aberration, can be significantly reduced by using a so-called threshold fabrication method. As a result, 3D fcc photonic crystals are fabricated by stacking quasi-spherical voids layer by layer.

Photonic bandgap properties of void-based body-centered-cubic photonic crystals in polymer.

We report on the fabrication and characterization of void-based body-centered-cubic (bcc) photonic crystals in a solidified transparent polymer by the use of a femtosecond laser-driven microexplosion method. The change in the refractive index in the region surrounding the void dots that form the bcc structures is verified by presenting confocal microscope images, and the bandgap properties are characterized by using a Fourier transform infrared spectrometer. The effect of the angle of incidence on the photonic bandgaps is also studied.

Use of ultrafast-laser-driven microexplosional for fabricating three-dimensional void-based diamond-lattice photonic crystals in a solid polymer material.

Micro-sized void spheres are successfully generated in a solid polymer by use of a tightly focused femtosecond laser beam from a high-repetition-rate laser oscillator. Confocal reflection images show that the void spheres are longitudinal rotational symmetric ellipsoids with a ratio of long to short axes of approximately 1.5.

Studies on the two-photon pumped upconverted fluorescence and superradiance of a new organic dye material in solutions.

The linear and nonlinear optical properties of a new organic dye, trans-4-[p-(N-ethyl-N-ethylamino)-styryl]-N-methyl-pyridinium tris(thiocyanato) cadmates (II), are reported in this paper. When pumped with a picosecond laser at the wavelength range of 850-1200 nm, intense upconversion fluorescence can be obtained. The upconversion efficiencies at different pump energies were measured when pumped with a 1064-nm laser beam from a mode-locked Nd:YAG laser.

Upconversion fluorescence and optical power limiting effects based on the two- and three-photon absorption process of a new organic dye BPAS.

A new organic dye, trans-4, 4'-bis(pyrrolidingl) stilbene (BPAS), with large two-photon absorption (TPA) and three-photon absorption (3PA) has been synthesized. The molecular TPA cross section sigma2' at 550-670 nm and the 3PA cross section sigma3' at 720-1000 nm have been measured. The biggest sigma2' and sigma3' was 5.