Nerve Block Extends Nerve Function Recovery in Patients with Diabetic Foot Ulcers.

Objective: Research has revealed that patients with diabetes and peripheral neuropathy exhibit significantly elevated nerve stimulation thresholds. However, the minimum stimulation thresholds of peripheral nerves in patients with diabetic foot, along with the recovery of nerve function, remain undetermined. The aim of this study is to investigate the minimum stimulation thresholds of the femoral and sciatic nerves, as well as the duration of nerve block, in patients diagnosed with diabetic foot.

Progress in the application of molecular imaging in psychiatric disorders.

Psychiatric disorders have always attracted a lot of attention from researchers due to the difficulties in their diagnoses and treatments. Molecular imaging, as an emerging technology, has played an important role in the researchers of various diseases. In recent years, molecular imaging techniques including magnetic resonance spectroscopy, nuclear medicine imaging, and fluorescence imaging have been widely used in the study of psychiatric disorders.

A Novel RAA Combined Test Strip Method Based on Dual Gene Targets for Pathogenic in Aquatic Products.

can cause disease in aquatic animals and humans, therefore, rapid and simple field detection of pathogenic is important for early disease prevention. In this study, a novel recombinase-aided amplification (RAA) combined test strip with double T-lines (RAA-TS-DTL) was developed for the rapid detection of in aquatic products. Pathogenic was detected using the virulence gene and the housekeeping gene gene as the dual target of the test strip.

Novel and portable test strip platform for rapid and sensitive on-site detection of procymidone pesticide.

A novel and portable detection platform for procymidone (PRM) was developed by combining simple sample pretreatment, lateral flow test strips based on multi-branched gold nanoparticle (LFTS-MBGNP), and a smartphone. Based on the large surface area of MBGNPs, rapid detection of PRM was realized by simple naked eye observation. By utilizing a smartphone as a portable signal analyzer, ultrasensitive quantitative detection of PRM in red wine was realized with the limits of detection (LOD) of 1.

SUMO specific peptidase 1 decreases after induction treatment, and its reduction predicts lower disease risk, better treatment response, longer survival of acute myeloid leukemia.

Small ubiquitin-related modifier-specific peptidase 1 (SENP1) takes part in the pathogenesis and progression of hematological malignancies, while its clinical role in acute myeloid leukemia (AML) is unclear. This study aimed to explore the potential of SENP1 to serve as a biomarker reflecting disease risk, treatment response, and survival of AML. A total of 110 AML patients, 30 disease controls (DCs), and 30 healthy controls (HCs) were included.

FDX1 serves as a prognostic biomarker and promotes glioma progression by regulating the immune response.

The present study investigates the prognostic value of the gene and its association with immune infiltration in gliomas. Gene expression profiles and corresponding clinical parameters of glioma patients were obtained from the Cancer Genome Atlas and Chinese Glioma Genome Atlas databases. experiments were also performed to validate its impact on malignant phenotypes of glioma cells.

Differences of injury characteristics of medial patellofemoral ligament in acute lateral patellar dislocation and multiligament knee injuries.

Background: The injury characteristics of medial patellofemoral ligament (MPFL) in multiligament knee injuries (MLKIs) and the differences of injury patterns of MPFL in MLKIs and acute lateral patellar dislocation (LPD) remain unclear.

Purpose: To explore the differences of injury characteristics of MPFL after acute LPD and MLKIs.

Methods: Magnetic resonance images were prospectively analyzed in 219 patients after acute LPD or MLKIs.

Iron Single Atoms-Assisted Cobalt Nitride Nanoparticles to Strengthen the Cycle Life of Rechargeable Zn-Air Battery.

The development of nonprecious metal catalysts with both oxygen reduction and evolution reactions (ORR/OER) is very important for Zn-air batteries (ZABs). Herein, a Co N particles and Fe single atoms co-doped hollow carbon nanofiber self-supporting membrane (H-CoFe@NCNF) is synthesized by a coaxial electrospinning strategy combined with pyrolysis. X-ray absorption fine spectroscopy analyses confirm the state of the cobalt nitride and Fe single atoms.

Copper Collector Generated Cu/Cu Redox Pair for Enhanced Efficiency and Lifetime of Zn-Ni/Air Hybrid Battery.

Although Zn-Ni/air hybrid batteries exhibit improved energy efficiency, power density, and stability compared with Zn-air batteries, they still cannot satisfy the high requirements of commercialization. Herein, the Cu/Cu redox pair generated from a copper collector has been introduced to construct the hybrid battery system by combining Zn-air and Zn-Cu/Zn-Ni, in which CuO@NiFe-LDH and Co-N-C dodecahedrons are respectively adopted as oxygen evolution (OER) and oxygen reduction (ORR) electrodes. For fabricating CuO@NiFe-LDH, the Cu foam collector is oxidized to form 1D CuO nanoneedle arrays, which could generate the Cu/Cu redox pair to enhance battery efficiency by providing an extra charging-discharging voltage plateau to reduce the charging voltage and increase the discharge voltage.

Reconstruction of Highly Dense Cu-N Active Sites in Electrocatalytic Oxygen Reduction Characterized by Operando Synchrotron Radiation.

The emerging star of single atomic site (SAS) catalyst has been regarded as the most promising Pt-substituted electrocatalyst for oxygen reduction reaction (ORR) in anion-exchange membrane fuel cells (AEMFCs). However, the metal loading in SAS directly affects the whole device performance. Herein, we report a dual nitrogen source coordinated strategy to realize high dense Cu-N SAS with a metal loading of 5.

Factors associated with acute articular cartilage lesions of the patella and lateral femoral condyle in acute first-time lateral patellar dislocation: A prospective magnetic resonance imaging study.

Objectives: To identify risk factors of acute articular cartilage lesions of the patella and lateral femoral condyle in acute first-time lateral patellar dislocation (LPD).

Methods: Magnetic resonance images were prospectively analyzed in 115 patients in an acute first-time LPD. Factors included gender, skeletal maturity, trochlear dysplasia, patellar height, and tibial tuberosity-trochlear groove (TT-TG) distance.

Clinical Utility of Red Blood Cell Distribution Width for the Diagnosis and Prognosis of Cervical Cancer.

Background: The width of red blood cell distribution (RDW) is correlated with some diseases, but its clinical value and prognostic role in cervical cancer is unclear.

Methods: We used receiver operating characteristic curves to evaluate the diagnostic ability of RDW and other clinical parameters in cervical cancer based on a case-control design. Using retrospective data, we explored the correlation of RDW with overall (OS) and progression-free (PFS) survival using Kaplan-Meier analysis and univariate and multivariate Cox regression with the hazard ratio (HR) and 95% confidence interval (CI).

Functional implications of aging-related lncRNAs for predicting prognosis and immune status in glioma patients.

This study is aimed to establish a new glioma prognosis model by integrating the aging-related lncRNA expression profiles and clinical parameters of glioma patients enrolled in the Chinese Glioma Genome Atlas and The Cancer Genome Atlas. The aging-related lncRNAs were explored using Pearson correlation analysis (|R|> 0.6, < 0.

Structural Design Strategy and Active Site Regulation of High-Efficient Bifunctional Oxygen Reaction Electrocatalysts for Zn-Air Battery.

Zinc-air batteries (ZABs) exhibit high energy density as well as flexibility, safety, and portability, thereby fulfilling the requirements of power batteries and consumer batteries. However, the limited efficiency and stability are still the significant challenge. Oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are two crucial cathode reactions in ZABs.

Maximal tumor diameter in the preoperative tumor magnetic resonance imaging (MRI) T2 image is associated with prognosis of Grade II Glioma.

Factors associated with the prognosis of low-grade glioma remain undefined. In this study, we examined whether the maximal tumor diameter in the preoperative tumor magnetic resonance imaging (MRI) T2 image is associated with the prognosis of grade II gliomas patients, aiming to provide insights into the clinical prediction of patient outcome.We retrospectively analyzed the clinical data of patients with Grade II glioma, who were hospitalized in Xiangya Hospital, Central South University, from 2011 to 2016.

Gender-related differences in concomitant articular injuries after acute lateral patellar dislocation.

Objectives: To explore the gender differences in the concomitant articular injuries after acute lateral patellar dislocation (LPD).

Methods: Magnetic resonance images were prospectively analyzed in 166 patients after an acute LPD. Concomitant articular injuries included bone contusion, medial patellofemoral ligament (MPFL) injury, articular cartilage lesion, and vastus medialis obliquus (VMO) lesion.

Plasma microRNA-720 may predict prognosis and diagnosis in glioma patients.

We enrolled 122 patients with glioma who received surgery treatment in our hospital from June 2010 to May 2012, and 60 healthy individuals. We found that the plasma miR-720 in the glioma group was significantly higher than that in the healthy control group (3.19 ± 1.

High Expression of CD44 Predicts a Poor Prognosis in Glioblastomas.

Purpose: Glioblastoma multiforme (GBM) is the most common of the malignant and invasive gliomas. High grade glioma is prone to relapse and has a poor prognosis. However, there is a big difference in terms of survival time with the same grade glioma.

Utility of Serum EB Virus Zta Antibody in the Diagnostic of Nasopharyngeal Carcinoma: Evidences From 2,126 Cases and 15,644 Controls.

We collected previous published data and performed a systematical assessment for the diagnostic value of serum Zta antibody in NPC patients. Using bivariate-mixed effect model, we calculated the sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnosis odds ratio (DOR), and summary receiver operating characteristics curve (AUC) and their 95% confidence intervals (CIs). We also performed subgroup analysis to explore the heterogeneity.

Assessment on clinical value of prostate health index in the diagnosis of prostate cancer.

In this study, we performed a comprehensive estimation and assessment for the clinical value of prostate health index (PHI) in diagnosing prostate cancer. Using the bivariate mixed-effect model, we calculated the following parameters and their 95% confidence internals (CIs), including sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio and symmetric receiver operator characteristic. Twenty eligible studies with a total number of 5543 subjects were included in the final analysis.

Prognostic value of magnetic resonance imaging features in low-grade gliomas.

The treatment strategy for low-grade gliomas (LGGs) is still controversial, and there are no standardized criteria to predict the prognosis of patients with LGGs. Magnetic resonance imaging (MRI) is a routine test for preoperative diagnosis for LGG and can reflect the destructive features for the tumor. In the present study, we aimed to explore the relationship between the MRI features and prognosis in patients with LGG.

Dose-dependent neurotoxicity caused by the addition of perineural dexmedetomidine to ropivacaine for continuous femoral nerve block in rabbits.

Objective: This study was designed to evaluate the neurotoxicity of dexmedetomidine combined with ropivacaine for continuous femoral nerve block in rabbits.

Methods: Thirty New Zealand rabbits were randomly divided into 5 groups of 6 rabbits each and received a continuous femoral nerve block with saline; 0.25% ropivacaine; or 1, 2, or 3 µg/mL of dexmedetomidine added to 0.

Serum proteomics identify potential biomarkers for nasopharyngeal carcinoma sensitivity to radiotherapy.

Radiotherapy is the primary treatment option for nasopharyngeal carcinoma (NPC). Local recurrence and metastasis caused by radioresistance become a bottleneck of curative effect for patients with NPC. Currently, serum predictive biomarkers of radioresistance are scare.

Incidence of second-time lateral patellar dislocation is associated with anatomic factors, age and injury patterns of medial patellofemoral ligament in first-time lateral patellar dislocation: a prospective magnetic resonance imaging study with 5-year follow-up.

Purpose: To examine the predictors of the second-time lateral patellar dislocation (LPD) in patients after acute first-time LPD in a 5-year follow-up.

Methods: Data were collected prospectively from patients after acute first-time LPD with conservative treatment. Factors included sex, age at the first-time LPD, anatomical variants [trochlear dysplasia, patellar height, tibial tuberosity-trochlear groove (TT-TG) distance], and injury patterns of medial patellofemoral ligament (MPFL) in acute first-time LPD.