Choroidal vascularity index in patients with computer vision syndrome combined with accommodative lead.

Background: This study aimed to investigate the choroidal vascularity index (CVI) in patients with computer vision syndrome (CVS) combined with accommodative lead.

Methods: This retrospective case-control study enrolled patients diagnosed with CVS and accommodative lead at University-Town Hospital of Chongqing Medical University between July 2022 and May 2023. The control group included individuals without any ocular diseases.

Host-guest interaction and properties of cucurbit[8]uril with chloramphenicol.

The interaction between cucurbit[8]uril (Q[8]) and chloramphenicol (CPE) was investigated using single-crystal X-ray diffraction spectroscopy, isothermal titration calorimetry (ITC) and UV-vis, NMR and IR spectroscopy. The effects of Q[8] on the stability, in vitro release performance and antibacterial activity of CPE were also studied. The results showed that CPE and Q[8] formed a 1:1 inclusion complex (CPE@Q[8]) with an inclusion constant of 5.

The fluorescence of a mercury probe based on osthol.

The ability of osthol (OST) to recognize mercury ions in aqueous solution was studied using fluorescence, UV-vis spectrophotometry, mass spectrometry, and H NMR spectroscopy, and the recognition mechanism is discussed. The results showed that OST and Hg can form a complex with a stoichiometric ratio of 1:1. The binding constant was 1.

Detecting Pesticide Dodine by Displacement of Fluorescent Acridine from Cucurbit[10]uril Macrocycle.

According to a simple guest-replacement fluorescence turn-on mechanism, we constructed a fluorescent probe system based on cucurbit[10]uril (Q[10]) and protonated acridine () to detect the pesticide dodine (). Formation of a homoternary inclusion complex @Q[10] in both aqueous solution and solid state was studied by means of H NMR spectroscopy and X-ray crystallography. Although can emit strong fluorescence in aqueous solution, the homoternary inclusion complex @Q[10] does not exhibit any fluorescence.

Cyanidin-3-O-glucoside attenuates high glucose-induced podocyte dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK pathway.

Diabetic nephropathy (DN) is a common and complicated chronic kidney disease around the world. To elucidate and find effective therapies of DN is of vital importance. In this paper, we have discovered that cyanidin-3-O-glucoside (C3G), which is one of the anthocyanins, could alleviate high glucose-induced podocyte dysfunction.

Host-guest interaction of cucurbit[8]uril with oroxin A and its effect on the properties of oroxin A.

In this study, we investigated the host-guest interactions between oroxin A (OA) and cucurbit[8]uril (Q[8]) using H NMR, MS, UV-vis and IR spectroscopy. The results showed that OA and Q[8] formed an inclusion compound (OA@Q[8]) with a molar ratio of 1:1 and a binding constant of 1.299 × 10 L·mol.

25-Hydroxyvitamin D3-deficiency enhances oxidative stress and corticosteroid resistance in severe asthma exacerbation.

Oxidative stress plays a significant role in exacerbation of asthma. The role of vitamin D in oxidative stress and asthma exacerbation remains unclear. We aimed to determine the relationship between vitamin D status and oxidative stress in asthma exacerbation.

Vitamin C mitigates oxidative stress and tumor necrosis factor-alpha in severe community-acquired pneumonia and LPS-induced macrophages.

Oxidative stress is an important part of host innate immune response to foreign pathogens. However, the impact of vitamin C on oxidative stress and inflammation remains unclear in community-acquired pneumonia (CAP). We aimed to determine the effect of vitamin C on oxidative stress and inflammation.