In smart classroom environments, accurately recognizing students' facial expressions is crucial for teachers to efficiently assess students' learning states, timely adjust teaching strategies, and enhance teaching quality and effectiveness. In this paper, we propose a student facial expression recognition model based on multi-scale and deep fine-grained feature attention enhancement (SFER-MDFAE) to address the issues of inaccurate facial feature extraction and poor robustness of facial expression recognition in smart classroom scenarios. Firstly, we construct a novel multi-scale dual-pooling feature aggregation module to capture and fuse facial information at different scales, thereby obtaining a comprehensive representation of key facial features; secondly, we design a key region-oriented attention mechanism to focus more on the nuances of facial expressions, further enhancing the representation of multi-scale deep fine-grained feature; finally, the fusion of multi-scale and deep fine-grained attention-enhanced features is used to obtain richer and more accurate facial key information and realize accurate facial expression recognition.
View Article and Find Full Text PDFThe difference in serum phospholipid content between stage-IV breast cancer patients and disease-free individuals was studied by employing a combination of chemometric statistical analysis tools and mass spectrometry. Chloroform-extracted serum samples were profiled for their lipid class composition and structure using precursor ion, neutral loss, and product ion tandem mass spectrometric (MS/MS) scanning experiments. Changes in the relative abundance of phospholipids in serum as a consequence of cancer progression, measured through electrospray ionization (ESI) mass spectrometry of flow-injected serum samples collected from 25 disease-free individuals and 50 patients diagnosed with stage-IV breast cancer, were statistically evaluated using principal component analysis (PCA), analysis of variance (ANOVA) and receiver operating characteristic (ROC) analysis.
View Article and Find Full Text PDFJ Chromatogr B Analyt Technol Biomed Life Sci
March 2008
A method to determine the catecholamine content in putamen (CPU) and midbrain (MB) regions of the brain of alcohol-preferring rats (P) is presented with a focus on the low-level detection of S,R-salsolinol, a metabolite of dopamine and a putative alcoholism marker. The developed strategy allows both quantitative profiling of related catecholamines and the enantiomeric separation and quantification of the S- and R-salsolinol isomers and their ratios. The described LC/MS strategy simplifies the current methodology that typically employs GC-MS by eliminating the need for derivatization.
View Article and Find Full Text PDFThere is increasing evidence that multivalency plays an important role in protein-lipid recognition and membrane targeting in biological systems. We describe here the preparation and characterization of multivalent analogues of the signaling lipid phosphatidylinositol-4,5-bisphosphate (PIP2). Tetherable analogues of the PIP2 headgroup were appended to polyamidoamine dendrimers via a squarate linker to afford polymers displaying four or eight headgroup moieties.
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
September 2006
A multi-particle ion trajectory simulation program ITSIM 6.0 is described, which is capable of ion trajectory simulations for electrode configurations with arbitrary geometries. The electrode structures are input from a 3D drawing program AutoCAD and the electric field is calculated using a 3D field solver COMSOL.
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
April 2006
A novel linear ion trap mass analyzer was developed using just four elongated planar electrodes, mounted in parallel, and employing an RF potential for ion trapping in the radial and axial directions. Mass analysis was achieved using the mass-selective instability scan with ion ejection in the radial direction. The performance of this new device was characterized in comparison with the 6-electrode rectilinear ion trap (RIT) from which it is derived.
View Article and Find Full Text PDFA mass analyzer based on a rectilinear geometry ion trap (RIT) has been built, and its performance has been characterized. Design concepts for this type of ion trap are delineated with emphasis on the effects of electrode geometry on the calculated electric field. The Mathieu stability region was mapped experimentally.
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