Publications by authors named "Guangshuai Li"

The arid and semi-arid regions of northwest China are characterized by sparse vegetation and fragile ecosystems, making them highly susceptible to the impacts of climate change and human activities. Based on observed meteorological data, the Normalized Difference Vegetation Index (NDVI), the Lund-Potsdam-Jena dynamic global vegetation model (LPJ), a vegetation recovery potential model, and the MK trend test method, this study investigated the spatiotemporal distribution of vegetation recovery potential in northwest China and its relationship with global warming and increasing precipitation. The results indicated that vegetation in northwest China significantly increased, with greening closely related to trends in warming and wetting during 1982-2019.

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Article Synopsis
  • The study investigates the effectiveness and safety of using botulinum toxin type A alongside sodium hyaluronate injections to treat midcheek grooves, which can negatively affect facial aesthetics.
  • Thirty-six participants with midcheek grooves underwent treatment, showing significant improvement in groove depth at various follow-up points without any severe adverse reactions.
  • Results indicated that the treatment was most effective for the medial midcheek groove at one month, while the lateral groove showed better results immediately after treatment, highlighting the influence of clinical subtypes on outcomes.
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Background: Dengue, a mosquito-borne viral disease, has occurred in many cities in China, and it tends to spread to higher latitudes (Huang et al., 2023). Xi'an, situated in central-west China, has witnessed an increase imported cases in the past few years, raising concerns of local dengue transmission.

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Background: Full-thickness skin grafts are widely used in plastic and reconstructive surgery. The main limitation of skin grafting is the poor textural durability and associated contracture, which often needs further corrective surgery. Excessive inflammation is the main reason for skin graft contractions, which involve overactivation of myofibroblasts.

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Background: Osteosarcoma (OS) is a primary malignant bone tumor in the pediatric and adolescent populations. Long non-coding RNAs (LncRNAs), such as plasma-cytoma variant translocation 1 (PVT1), have emerged as significant regulators of OS metastasis. Recent studies have indicated that activation of signal transducer and activator of transcription 3 (STAT3) signaling, which might be controlled by PVT1, inhibits ferroptosis to promote the malignant progression of cancer.

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Objective: To investigate the causal relationship between poor lifestyle habits, such as smoking and drinking, and cutaneous malignant melanoma.

Method: In the present study, alcohol consumption and smoking were used as exposure factors, and single nucleotide polymorphisms closely associated with alcohol consumption and smoking were used as instrumental variables, while cutaneous melanoma was set as an outcome variable. Two-sample Mendelian randomization analyses were run between alcohol consumption and melanoma and smoking and melanoma to investigate their causal associations, respectively.

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Background: Several recent observational studies have associated obesity, lifestyle factors (smoking, sleep duration, and alcohol drinking), and glycemic traits with facial aging. However, whether this relationship is causal due to confounding and reverse causation is yet to be substantiated.

Aims: We aimed to assess these relationships using Mendelian randomization (MR).

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The Heilongjiang-Amur River Basin is one of the largest and most complex aquatic systems in Asia, comprising diverse wetland resources. The wetland vegetation in mid-high latitude areas has high natural value and is sensitive to climate changes. In this study, we investigated the wetland vegetation cover changes and associated responses to climate change in the Heilongjiang-Amur River Basin from 2000 to 2018 based on the growing season (May to September) climate and LAI data.

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Background: Melanoma is a common cancer that causes a severe socioeconomic burden. Patients usually turn to plastic surgeons to determine their prognosis after surgery.

Methods: Data from hundreds of thousands of real-world patients were downloaded from the Surveillance, Epidemiology, and End Results database.

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Malignant melanoma (MM) is a neoplasm that develops from human melanocytes. It was reported that eukaryotic translation initiation factor 3 subunit B (EIF3B) is associated with multiple types of cancers, but its role in MM has not been reported. In the present study, we found that EIF3B was abundantly expressed in MM and was strongly related to lymphatic metastasis and pathological stage of MM patients.

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Background: Benign parotid hypertrophy makes the earlobe area appear swollen and weakens the lateral facial contour and aesthetics. Efficacious treatment for benign parotid hypertrophy is not available. The authors evaluated the efficacy and safety of botulinum toxin type A for benign parotid hypertrophy treatment.

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Background: Laser and intense pulsed light (IPL) therapies have shown promising effects on pathological scars, but the comparative effectiveness of laser and IPL therapies has not yet been studied.

Objectives: The aim of this study was to compare and rank the efficacy of laser and IPL therapies to determine the most effective treatment method for pathological scars.

Methods: Relevant studies published up to February 2022 were identified by searching PubMed, Web of Science, Cochrane Library, CNKI, and Wanfang databases.

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The Heilong-Amur River Basin (HARB) in Northeast Asia has experienced distinct land surface changes during the past 40 years due to extensive ecological restoration programs, agricultural management, and grassland grazing in different ecosystems. However, the regional climate impact caused by the long-term spatially heterogeneous land surface changes in this mid-high latitude region is not well documented. Therefore, this study used multi-source satellite measurements records and a high-resolution land-atmosphere coupled regional climate model (WRF) to investigate the land surface changes and their associated thermal and moisture impacts across three main ecosystems over the Heilong-Amur River basin from 1982 to 2018.

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Background: Hypertrophic scar (HTS) is a fibrotic disorder of skins and may have repercussions on the appearance as well as functions of patients. Recent studies related have shown that competitive endogenous RNA (ceRNA) networks centering around miRNAs may play an influential role in HTS formation. This study aimed to construct and validate a three-miRNA (miR-422a, miR-2116-3p, and miR-3187-3p) ceRNA network, and explore its potential functions.

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Early postoperative injection of botulinum toxin type A (BTxA) can reduce surgical scar hypertrophy. BTxA injection at different time points is associated with different levels of efficacy, but the efficacy of different doses of BTxA for scar management has not investigated. The purpose of this study was to investigate the effect of different doses of BTxA administered early after surgery on scar improvement through a split-scar experiment.

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Circular RNA protein kinase, DNA-activated, catalytic subunit (circ_PRKDC) has been found to impede wound healing in diabetic foot ulcers via regulating keratinocyte proliferation and migration. However, the mechanisms underlying circ_PRKDC in skin wound healing remain unclear. The expression of circ_PRKDC, microRNA (miR)-31 and fibrillin 1 (FBN1) was detected using quantitative reverse transcription-polymerase chain reaction and Western blot assays.

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Background: The unprecedented COVID-19 pandemic has brought drastic changes to the field of plastic surgery. It is critical for stakeholders in this field to identify the changes in public interest in plastic procedures to be adequately prepared to meet the challenges of the pandemic.

Objective: The aim of this study is to examine tweets related to the public interest in plastic procedures during the COVID-19 pandemic and to help stakeholders in the field of plastic surgery adjust their practices and sustain their operations during the current difficult situation of the pandemic.

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Keloid is a skin disease characterized by fibrous hyperplasia, which is often difficult to cure. Long non-coding RNAs (lncRNAs) have been shown to be associated with the development of many diseases. However, the role and mechanism of lncRNA H19 in keloid has been less studied.

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