Analysis of CD8 TCRβ Chain repertoire in peripheral blood of vitiligo via high-throughput sequencing.

Vitiligo is an autoimmune depigmentation dermatosis induced by melanocyte destruction, and CD8 T cells play a pivotal role in melanocyte destruction. However, an accurate profile of the CD8 T cell receptor (TCR) repertoire in vitiligo patients has not been reported, and the clonotype features of the involved CD8 T cells remain largely unknown. This study aimed to assess the TCRβ chain repertoire diversity and composition of blood in nine nonsegmental vitiligo patients via high-throughput sequencing.

Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Atopic Dermatitis Symptoms in Mice through Modulating Immune Balance and Skin Barrier Function.

Atopic dermatitis (AD) is a chronic skin inflammatory disease associated with immune abnormalities and disrupted skin barrier function. Mesenchymal stem cells (MSCs) have been suggested as an alternative therapeutic option in AD. Stem cells from human exfoliated deciduous teeth (SHEDs) are a unique postnatal stem cell population with high immunomodulatory properties.

Warfarin-induced Stevens-Johnson syndrome with severe liver injury.

Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening mucocutaneous disease that is predominantly drug-induced. Warfarin is the most commonly used drug for long-term anti-coagulant therapy; however, warfarin-induced SJS/TEN is seldom reported. In this study, we presented the case of a 61-year-old man who developed SJS after receiving multiple-drug therapy following aortic valve replacement surgery.

Fluxes of CH4 and N2O from soil under a tropical seasonal rain forest in Xishuangbanna, Southwest China.

CH4 and N2O fluxes from soil under a tropical seasonal rain forest in Xishuangbanna, Southwest China were measured for one year using closed static chamber technique and gas chromatography method. Three treatments were set in the studied field: (A) litter-free, (B) with litter, and (C) with litter and seedling. The results showed that the soil in our study was a sink of atmospheric CH4 and source of atmospheric N2O.

[On-line analysis and mass concentration characters of the alkali metal ions of PM10 in Beijing].

The mass concentration characters and the sources of water-soluble alkali metal ions in PM10 in 2004 and 2005 in Beijing were analyzed by using the system of rapid collection of particles. The result showed that the average concentration of Na+, K+, Mg2+ and Ca2+ was 0.5-1.

Prognosis of unclassified eczema: a follow-up study.

Objective: To investigate the outcome of unclassified eczema (UE). Eczema refers to a set of highly heterogeneous clinical conditions including contact dermatitis (CD) and several types of endogenous eczema. In clinics, however, the eczema of a large proportion of patients does not fit any known patterns and has been diagnosed as unclassified eczema.

Etiology and prognosis of hand eczema in a dermatology clinic in China: a follow-up study.

Background: Prognosis of hand eczema (HE) has not been reported in China.

Objectives: To investigate the etiology and outcome of HE in 655 consecutive patients patch tested with European standard series in Peking University Hospital in a 2-year period.

Methods: All patients were re-examined at 1 year after patch testing, and prognosis of dermatitis was evaluated by the rate of clearance of skin symptoms for at least 3 months without relapse before the evaluation.

Prevalence and 1-year outcome of facial allergic contact dermatitis in patients patch tested in a university hospital.

Little is known about the prognosis of facial allergic contact dermatitis (FACD). The objective of the study was to investigate the prevalence and 1-year outcome of FACD in patients patch tested. 655 consecutive patients patch tested with European standard series in Peking University Hospital in a 2-year period were studied.

[Water-soluble chloride in aerosol PM10 in Beijing].

Water-soluble chloride is one of the most important components in aerosols. The chloride in PM10 measured from January to December 2004 in Beijing was determined using a system by combing rapid collection of fine particles and ion chromatography (RCFP-IC). The results showed that the annual average concentration of water-soluble chloride at the urban area in Beijing was about (3.

An improved gas chromatography for rapid measurement of CO2, CH4 and N2O.

Combining improved injector, gas line and valve-driving modules, a GC equipped with FID and ECD, could simultaneously measure CH4, CO2 and N2O in an air sample within 4 min. Test results showed that the system has high sensitivity, resolution and precision; the linear response range of the system meets the requirement of in situ flux measurements. Thus, the system is suitable for monitoring fluxes of main greenhouse gases in terrestrial ecosystem since it is easy to use, efficacious, stable and reliable to collect data.

[Trends and variation of CFC-11 in the atmosphere of Beijing].

In recent years, concentration of CFC in the atmosphere has undergone rapid changes especially in association with human activities. For the influence of CFC on climate changes and environment changes, the concentration of atmospheric CFC-11 in Beijing is continuously observed and analyzed by a gas chromatography-mass spectrometry. The seasonal variation concentration and trends of CFC-11 are reported.

[Measurement and study on the atmospheric trace BTEX in Beijing].

Atmospheric trace BTEX in Beijing was observed by a gas chromatography/mass spectrometry in the latest 4 years. The diurnal, lunar and annual concentration variations of these pollutants were reported. In winter and spring, the diurnal profiles exhibited two peak values corresponding to the daily rush hours 08:00-10:00 am and 17:00 pm; in autumn, there was the third peak value in the night at 22:00; the highest concentration of BTEX in summer appeared in the midday and totally three daily maxima were in the sampled day.

[Characteristics of atmospheric CO2 variations and some affecting factors in urban area of Beijing].

The diurnal variation of the atmospheric CO2 at the urban area in Beijing displayed a very clear cycle, generally with the lowest value being recorded at about 15:00 local time and the highest in the nighttime. The differences between the maximums and the minimums ranged from 23.2 to 39.

[Greenhouse gases emission or uptake in Inner Mongolia natural and free-grazing grasslands].

GC-MS was used to measure the greenhouse emission of Inner Mongolia Grassland. The results showed that four kinds of typical semi-arid grasslands in Inner Mongolia had their own special seasonal patterns as the source of atmospheric N2O and CO2 emission and the sink of atmopsheric CH4, which were controlled by seasonal weather variation. Different soil and vegetation types and precipitation influenced the intensity of emission and upatake of the gases.