Cerebral blood flow in the paracentral lobule is associated with poor subjective sleep quality among patients with a history of methadone maintenance treatment.

Introduction: Sleep disorders are prevalent and significant among individuals receiving methadone maintenance treatment (MMT), adversely affecting their quality of life and treatment adherence. While cerebral blood flow (CBF) plays a crucial role in the development of various diseases, its relationship with sleep disorders remains uncertain. This observational study focuses on possible correlations between CBF and poor subjective sleep quality in MMT patients.

Effects of exercise interventions on negative emotions, cognitive performance and drug craving in methamphetamine addiction.

Introduction: Methamphetamine is currently one of the most commonly used addictive substances with strong addiction and a high relapse rate. This systematic review aims to examine the effectiveness of physical activity in improving negative emotions, cognitive impairment, and drug craving in people with methamphetamine use disorder (MUD).

Methods: A total of 17 studies out of 133 found from Embase and PubMed were identified, reporting results from 1836 participants from MUD populations.

Progress in the study of intestinal microbiota involved in morphine tolerance.

Morphine is a widely used opioid for treatment of pain. The attendant problems including morphine tolerance and morphine dependence pose a major public health challenge. In recent years, there has been increasing interest in the gastrointestinal microbiota in many physiological and pathophysiological processes.

Triple roles of Ni(OH) promoting the electrocatalytic activity and stability of NiS@Ni(OH) in anion exchange membrane water electrolyzers.

Developing high performance and durable electrocatalysts is crucial for the practical application of large-scale water splitting under high current density. Here, we constructed a Mott-Schottky heterojunction bifunctional electrocatalyst coating of NiS with Ni(OH) thin film supported on Ni foam substrate (NiS@Ni(OH)) for anion exchange membrane water electrolyzers (AEMWEs). Remarkably, the η is as low as 274.

3D Dirac semimetal supported thermal tunable terahertz hybrid plasmonic waveguides.

By depositing the trapezoidal dielectric stripe on top of the 3D Dirac semimetal (DSM) hybrid plasmonic waveguide, the thermal tunable propagation properties have been systematically investigated in the terahertz regime, taking into account the influences of the structure of the dielectric stripe, temperature and frequency. The results manifest that as the upper side width of the trapezoidal stripe increases, the propagation length and figure of merit (FOM) both decrease. The propagation properties of hybrid modes are closely associated with temperature, in that when the temperature changes in the scope of 3-600 K, the modulation depth of propagation length is more than 96%.

A multifunctional cobalt-organic framework for proton conduction and selective sensing of Fe ions.

Developing multifunctional metal-organic frameworks (MOFs) is a new research trend. MOFs have shown remarkable performances in both proton conduction and fluorescence sensing, but the MOFs integrating the two performances are scarce. Herein, a Co-MOF, [Co(oba)(Hatz)(atz)(HO)(μ-OH)(μ-OH)]·HO (1, Hoba = 4,4-oxybis(benzoic acid), Hatz = 5-amino-1 tetrazole), has been assembled by Co ions with Hoba and Hatz ligands, providing a unique example of multifunctional MOFs with both proton conduction and fluorescence sensing performances.

3D Dirac semimetals-dielectric elliptical fiber supported tunable terahertz hybrid waveguide.

Based on the proposed elliptical dielectric fiber-polyethylene gap-3D Dirac semimetal (DSM) hybrid plasmonic waveguide structure, the tunable propagation characteristics have been systematically investigated in the terahertz region, taking into account the influences of the structural parameters, the modified dielectric fiber, and the 3D DSM Fermi levels. The results show that as the ratio of the elliptical semi-axis along the -direction and the -direction (/) increases, the hybrid mode confinement increases. The real part of the effective mode index and propagation length increase with increasing the refractive index of the elliptical fiber.

A flexible control on electromagnetic behaviors of graphene oligomer by tuning chemical potential.

In this work, we demonstrate that the electromagnetic properties of graphene oligomer can be drastically modified by locally modifications of the chemical potentials. The chemical potential variations of different positions in graphene oligomer have different impacts on both extinction spectra and electromagnetic fields. The flexible tailoring of the localizations of the electromagnetic fields can be achieved by precisely adjusting the chemical potentials of the graphene nanodisks at corresponding positions.

Optimization of the Fano Resonance Lineshape Based on Graphene Plasmonic Hexamer in Mid-Infrared Frequencies.

In this article, the lineshape of Fano-like resonance of graphene plasmonic oligomers is investigated as a function of the parameters of the nanostructures, such as disk size, chemical potential and electron momentum relaxation time in mid-infrared frequencies. Also, the mechanism of the optimization is discussed. Furthermore, the environmental index sensing effect of the proposed structure is revealed, and a figure of merit of 25.

Lipschitz estimates for commutators of singular integral operators associated with the sections.

Let be Monge-Ampère singular integral operator, [Formula: see text], and [Formula: see text]. It is proved that the commutator [Formula: see text] is bounded from [Formula: see text] to [Formula: see text] for [Formula: see text] and from [Formula: see text] to [Formula: see text] for [Formula: see text]. For the extreme case [Formula: see text], a weak estimate is given.

An energy harvesting type ultrasonic motor.

An energy harvesting type ultrasonic motor is presented in this work. The novel motor not only can drive and/or position the motion mechanism, but also can harvest and convert the vibration-induced energy of the stator into electric energy to power small electronic devices. In the new motor, the stator is a sandwich structure of two PZT rings and an elastic metal body.

Overexpression of Hypo-Phosphorylated IκBβ at Ser313 Protects the Heart against Sepsis.

IκBβis an inhibitor of nuclear factor kappa B(NF-κB) and participates in the cardiac response to sepsis. However, the role of the hypo-phosphorylated form of IκBβ at Ser313, which can be detected during sepsis, is unknown. Here, we examined the effects of IκBβ with a mutation at Ser313→Ala313 on cardiac damage induced by sepsis.

[Debridement of burn wounds using a hydrosurgery system].

The healing process of burn wounds is strongly associated with the depth of wounds, and the depth of wounds is dependent to initial temperature and duration of contact with source of heat, infection, and secondary damage in the debridement process. On this basis, some experts present a concept of accurate debridement, which denotes removal of all necrotic tissue and at the same time protecting viable tissue for repair of raw wounds in order to maximally maintain patients' appearance and functions. A new technology of burn wound debridement--hydrosurgery system has been applied clinically.

Monocyte subsets and their differentiation tendency after burn injury.

Monocytes are critical effectors and regulators of immune response. Studying the nomenclature of monocyte subsets may be beneficial for understanding the complex function of monocytes in steady and inflammatory states. A monocyte has the potential to differentiate into dendritic cells or macrophages, and this behavior significantly changes in severely burned patients and mice.

Mechanism and cellular kinetic studies of the enhancement of antioxidant activity by using surface-functionalized gold nanoparticles.

The enhanced antioxidant activity of surface-functionalized gold nanoparticles (AuNPs) synthesized by self-assembly has attracted great attention, but little is known about the mechanism behind the enhanced activity. To address this challenge, the antioxidant activity of Au@PEG3SA (i.e.

Pathogenic alteration in severe burn wounds.

The present study aims to define the trend of time related changes with local bacterial alteration of bacterial resistance in severe burns in our burn center during a 12-year period. Retrospective analysis of microbiological results on severely burned wounds between 1998 and 2009 was carried out. A study of 3615 microbial isolates was performed.

Successful treatment of a patient with an extraordinarily large deep burn.

Background: Treatment of extraordinarily large deep burns remains a huge clinical challenge.

Case Report: This article is a summary of our experience with the treatment of a patient with an extraordinarily large deep burn (99.5% TBSA and 23% fourth degree burn) by using the "microskin autografting and alloskin repeated grafting" method to close the deep burn wound because of scarcity of skin sources of the patient.

Reduction of CD47 on monocytes correlates with MODS in burn patients.

Alternation of surface markers on monocytes is associated with the development of inflammation. The goals of the present study were to detect CD47 expression on monocytes by flow cytometry and explore its relationship with disease severity and MODS in burned patients. The results show CD47 expression on monocytes from all burned patients (n = 21) was lower than that from the healthy population (n = 21) for 24 days after burn.

Biphasic effects of selective inhibition of transforming growth factor beta1 activin receptor-like kinase on LPS-induced lung injury.

The present study was designed to find out whether SB431542, an inhibitor of transforming growth factor beta1 activin receptor-like kinase, could protect the lung from LPS-induced injury. Inflammatory lung injury model was induced by intratracheal administration of LPS. C57BL/6 mice were randomly divided into the sham control group (S group), the LPS stimulation group (L group), the LPS + early SB431542 treatment group (Ie group), and the LPS + delayed SB431542 treatment group (Id group).

Tec kinase mediating IL-8 transcription in monocytes stimulated with LPS.

The purpose of present study was to explore the possibility of Tec kinase as a mediator for IL-8 transcription in monocytes stimulated with LPS. Plasmids of mouse Tec kinase IV or Tec kinase IV with inactivating point mutations generated with QuikChange site-directed mutagenesis were co-transfected with IL-8 promoter driven luciferase construct into RAW264.7 cells, then luciferase activity was measured with a luminometer.

The direct hospitalisation costs of paediatric scalds: 2-year results of a prospective case series.

Objective: To reveal the characteristic and distribution of length of hospital stay (LOS) and direct hospitalisation costs of paediatric scald.

Methods: A prospective case series observation was performed from January 2005 to December 2006 at the Burn Center, Changhai Hospital, Shanghai, China. The information, such as demographics, clinical diagnosis and treatments since admission, of the paediatric scald patients included in the series was recorded.

Transplantation of epidermis of scar tissue on acellular dermal matrix.

This study enrolled 22 participants with hypertrophic scarring after burn who received treatment with co-transplantation of acellular dermal matrix and epidermis of either normal skin or scar tissue. Scar thickness was evaluated with high frequency ultrasonography and the distribution of keratinocyte stem cells was detected by immunostaining. The results showed p63-positive keratinocyte stem cells throughout the epidermis of scar tissue.

Prevention and treatment of gastrointestinal dysfunction following severe burns: a summary of recent 30-year clinical experience.

Aim: To sum up the recent 30-year experience in the prevention and treatment of gastrointestinal dysfunction in severe burn patients, and propose practicable guidelines for the prevention and treatment of gastrointestinal (GI) dysfunction.

Methods: From 1980 to 2007, a total of 219 patients with large area and extraordinarily large area burns (LAB) were admitted, who were classified into three stages according the therapeutic protocols used at the time: Stage 1 from 1980 to 1989, stage 2 from 1990 to 1995, and stage 3 from 1996 to 2007. The occurrence and mortality of GI dysfunction in patients of the three stages were calculated and the main causes were analyzed.

[Reconstruction and transplantation of the composite skin comprising epithelial growth factor gene-transfected keratinocytes].

Objective: To investigate the epithelial growth factor (EGF) expression of EGF gene-transfected keratinocytes and its effect on cell proliferation after grafting.

Methods: Newborn Balb/c mouse keratinocytes and gene transfected keratinocytes were seeded on the surface of acellular dermal matrix and cocultured in different ratios as follows: 1:1, 1:3, or 1:5 1 week after culture. The composite skin was grafted onto the full-thickness wound in Balb/c mouse.