Spontaneous type 2 diabetes mellitus (T2DM) macaques are valuable resources for our understanding the pathological mechanism of T2DM. Based on one month's fasting blood glucose survey, we identified seven spontaneous T2DM macaques and five impaired glucose regulation (IGR) macaques from 1408 captive individuals. FPG, HbA1c, FPI and IR values were significant higher in T2DM and IGR than in controls.
View Article and Find Full Text PDFMicrobial enhanced oil recovery (MEOR) is a potential tertiary oil recovery method. However, past research has failed to describe microbial growth and metabolism reasonably, especially quantification of reaction equations and operating parameters is still not clear. The present study investigated the ability of bacteria extracted from Ansai Oilfield for MEOR.
View Article and Find Full Text PDFDue to the inefficient reproduction of microorganisms in oxygen-deprived environments of the reservoir, the applications of microbial enhanced oil recovery (MEOR) are restricted. To overcome this problem, a new type of air-assisted MEOR process was investigated. Three compounding oil degradation strains were screened using biochemical experiments.
View Article and Find Full Text PDFThe high incidence of bacterial vaginosis recurrence is common after treatment with an antibiotic agent and suggests the need for new treatments to prevent this. We conducted a randomized trial to evaluate the ability of maltose gel to treat bacterial vaginosis. Eighteen female rhesus macaques were randomly assigned, in a 2:1 ratio, to receive maltose gel or placebo gel by syringe to the fornix of the vagina for five consecutive days.
View Article and Find Full Text PDFAging is a very complicated biological process that can change gene expressions. The Chinese rhesus macaque (Macaca mulatta lasiota; CR) is closely related to humans. We explored gene expression with increasing age and DNA methylation changes in young and old CRs.
View Article and Find Full Text PDFKnowledge of the transport and retention behaviors of soft deformable particles on the microscale is essential for the design, evaluation, and application of engineered particle materials in the fields of energy, environment, and sustainability. Emulated convergent-divergent microchannels were constructed and used to investigate the transport and retention behaviors of soft deformable polyacrylamide microspheres at various conditions. Five different types of transport and retention patterns, i.
View Article and Find Full Text PDFDuring the breast-feeding period, infants undergo remarkable changes, including rapid physiological and developmental growth. However, little is known about gene expression features and sex-specific gene expression in breast-feeding infants. In this study, we sequenced 32 blood transcriptomes from 16 breast-feeding rhesus macaque ( ) infants and their lactating mothers.
View Article and Find Full Text PDFKnowledge of micrometer-size polyacrylamide elastic microsphere (MPEM) transport and retention mechanisms in porous media is essential for the application of MPEMs as a smart sweep improvement and profile modification agent in improving oil recovery. A transparent micromodel packed with translucent quartz sand was constructed and used to investigate the pore-scale transport, surface deposition-release, and plugging deposition-remigration mechanisms of MPEMs in porous media. The results indicate that the combination of colloidal and hydrodynamic forces controls the deposition and release of MPEMs on pore-surfaces; the reduction of fluid salinity and the increase of Darcy velocity are beneficial to the MPEM release from pore-surfaces; the hydrodynamic forces also influence the remigration of MPEMs in pore-throats.
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