The Different Welding Layers and Heat Source Energy on Residual Stresses in Swing Arc Narrow Gap MAG Welding.

In this paper, in order to reduce the time cost of prediction experiments in industry, a new narrow gap oscillation calculation method is developed in ABAQUS thermomechanical coupling analysis to study the distribution trend of residual weld stresses in comparison with conventional multi-layer welding processes. The blind hole detection technique and thermocouple measurement method verify the reliability of the prediction experiment. The results show that the experimental and simulation results have a high degree of agreement.

Elevated CEA and CA 19-9 Levels within the Normal Ranges Increase the Likelihood of CRC Recurrence in the Chinese Han Population.

Objective: This study aimed to determine if variations in the expression profiles of CA 19-9 and carcinoembryonic antigen (CEA) within the reference range could serve as possible biomarkers for postoperative CRC recurrence.

Method: This retrospective cohort investigation enrolled 2,596 cases of CRC that received curative surgery. Serum CEA/CA 19-9 were measured through chemiluminescence immunoassay (CLIA).

Cdc14a has a role in spermatogenesis, sperm maturation and male fertility.

Cdc14a is an evolutionarily conserved dual-specific protein phosphatase, and it plays different roles in different organisms. Cdc14a mutations in human have been reported to cause male infertility, while the specific role of Cdc14a in regulation of the male reproductive system remains elusive. In the present study, we established a knockout mouse model to study the function of Cdc14a in male reproductive system.

Knock-In Mice with Myo3a Y137C Mutation Displayed Progressive Hearing Loss and Hair Cell Degeneration in the Inner Ear.

Myo3a is expressed in cochlear hair cells and retinal cells and is responsible for human recessive hereditary nonsyndromic deafness (DFNB30). To investigate the mechanism of DFNB30-type deafness, we established a mouse model of Myo3a kinase domain Y137C mutation by using CRISPR/Cas9 system. No difference in hearing between 2-month-old Myo3a mutant mice and wild-type mice was observed.