Publications by authors named "Guangjiao Yin"
Effect of fat distribution on left ventricular structure and function in different sexes: a Mendelian randomization study.
Front Endocrinol (Lausanne)
March 2025
Background: Although there is an interaction between sex, body fat distribution, and cardiac structure and function, these relationships have not been fully elucidated yet. This study aims to reveal the causal relationship between genetic determinants of fat distribution pattern and function of the left ventricular structure in different sexes.
Methods: Genetic variants for waist circumference, hip circumference, waist-to-hip ratio (WHR), and body mass index (BMI) were selected from genome-wide association studies conducted in European samples.
The burden of sarcopenia is increasing worldwide. However, most cases of sarcopenia are undiagnosed due to the lack of simple screening tools. This study aimed to develop and validate an individualized and simple nomogram for predicting sarcopenia in older adults.
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- * A 14-year-old male presented with high fever, worsening symptoms, and was diagnosed with HLH through various laboratory tests showing cytopenia and hemophagocytosis in the bone marrow.
- * Genetic analysis identified two new mutations that likely triggered HLH, and after receiving timely treatment, the patient's condition improved, highlighting the importance of early diagnosis and supportive care.