Clinical study of two reversible arterial blockade methods in the treatment of scar pregnancy under combined hysterolaparoscopy.

Objective: To assess and compare the clinical efficacy of scar pregnancy debridement by a combination of reversible bilateral uterine and internal iliac artery blockade with hysterolaparoscopy, as a management strategy for cesarean scar pregnancy.

Methods: This retrospective study included patients diagnosed with cesarean scar pregnancy who underwent combined surgical intervention involving hysteroscopy and laparoscopy between May 2020 and February 2024. The study population was divided into two groups based on the type of arterial blockade used: a uterine artery blockade group and an internal iliac artery blockade group.

Analysis of ventricular-vascular properties during preeclampsia: an echocardiography study.

The aim of the study is to analyze ventricular-vascular properties with different ventricular-arterial coupling (VAC) ratio in the preeclamptic women. Seventy-seven pregnant women with preeclampsia and eighty-nine with normal pregnancy were performed echocardiography. VAC was defined as the ratio between aortic elastance (Ea) and left ventricular (LV) end-systolic elastance (Ees).

Conductive/Insulating Bioinks with Multitechnology Compatibility and Adjustable Performance.

Conducting/insulating inks have received significant attention for the fabrication of a wide range of additive manufacturing technology. However, current inks often demonstrate poor biocompatibility and face trade-offs between conductivity and mechanical stiffness under physiological conditions. Here, conductive/insulating bioinks based on two-dimensional materials are proposed.

The coexistence of myosteatosis and the creatinine/cystatin C ratio are determinants of outcomes in cholangiocarcinoma patients undergoing curative surgery.

Background: Myosteatosis is a well-established predictor of poor prognosis in many types of cancer, and a decreased Creatinine/Cystatin C ratio (CCR) is a known indicator of unfavorable outcomes in patients with metabolic disorders and cancer. Despite this knowledge, the significance of concurrent CCR and myosteatosis in predicting the prognosis of patients with cholangiocarcinoma (CCA) who undergo radical surgery remains uncertain.

Method: Data from 757 patients with cholangiocarcinoma who underwent the first radical resection in the Affiliated Hospital of Qingdao University from January 2017 to March 2022 were collected.

Application of Hashin-Shtrikman bounds homogenization model for frequency analysis of imperfect FG bio-composite plates.

Despite abundant theoretical investigations on the dynamic behavior of functionally graded (FG) structures, the study on frequency analysis of FG bio-composite structures is limited. FG bio-composite materials due to their biocompatibility potentials and good material properties can be applied in biomedical applications, especially dental implants. In this investigation, a natural frequency response of the FG bio-composite plate is analyzed within the framework of the newly developed refined higher-order shear deformation plate theory.

ADSC-derived exosomes-coupled decellularized matrix for endometrial regeneration and fertility restoration.

Endometrium is suspectable to severe injury due to recurrent abortion, curettage or intrauterine infection which could lead to pathological conditions and sabotage women's fertility. Promoting endometrium regeneration is the core of the treatments to uterine related infertility. Patients who received traditional treatments can only expect limited effects, thereby novel therapies are badly in need to promote endometrium regeneration.

Reduced CPU Workload for Human Pose Detection with the Aid of a Low-Resolution Infrared Array Sensor on Embedded Systems.

Modern embedded systems have achieved relatively high processing power. They can be used for edge computing and computer vision, where data are collected and processed locally, without the need for network communication for decision-making and data analysis purposes. Face detection, face recognition, and pose detection algorithms can be executed with acceptable performance on embedded systems and are used for home security and monitoring.

Differential Diagnosis of Benign and Malignant Pulmonary Nodules in CT Images Based on Multitask Learning.

Background: Artificial intelligence-based aided diagnostic systems for pulmonary nodules can be divided into subtasks such as nodule detection, segmentation, and benign and malignant differentiation. Most current studies are limited to single-target tasks. However, aided diagnosis aims to distinguish benign from malignant pulmonary nodules, which requires the fusion of multiple-scale features and comprehensive discrimination based on the results of multiple learning tasks.

Noninvasive grading of glioma brain tumors using magnetic resonance imaging and deep learning methods.

Purpose: Convolutional Neural Networks (ConvNets) have quickly become popular machine learning techniques in recent years, particularly in the classification and segmentation of medical images. One of the most prevalent types of brain cancers is glioma, and early, accurate diagnosis is essential for both treatment and survival. In this study, MRI scans were examined utilizing deep learning techniques to examine glioma diagnosis studies.

Evaluating the characteristics of myocardial work by two-dimensional echocardiography during pre-eclampsia pregnancy.

This study aimed to analyze the changes in myocardial work (MyW) properties and the correlation of MyW with cardiovascular and clinical indices during the pre-eclampsia (PE) pregnancy. Standard two-dimensional and speckle-tracking echocardiography were sequentially performed on 77 women with PE and 89 with normal pregnancy. Four components of MyW: global myocardial work index (GWI), constructive work (GCW), wasted work (GWW), and work efficiency (GWE) were measured.

Quantification of Myocardial Work by 2-D Echocardiography during a Normal Pregnancy: A Preliminary Study.

This study was aimed at investigating the adaptive changes in myocardial work (MyW) during normal pregnancy. Sequential 2D standard and speckle-tracking echocardiography was performed on 41 pregnant women in each gestational trimester and 4 to 11 mo after delivery. Thirty-eight age-matched, healthy, non-pregnant women served as controls.

Molecular classification of human papillomavirus-positive cervical cancers based on immune signature enrichment.

Background: Human papillomavirus-positive (HPV+) cervical cancers are highly heterogeneous in clinical and molecular characteristics. Thus, an investigation into their heterogeneous immunological profiles is meaningful in providing both biological and clinical insights into this disease.

Methods: Based on the enrichment of 29 immune signatures, we discovered immune subtypes of HPV+ cervical cancers by hierarchical clustering.

A Multimodel Fusion Method for Cardiovascular Disease Detection Using ECG.

. Electrocardiogram (ECG) is an important diagnostic tool that has been the subject of much research in recent years. Owing to a lack of well-labeled ECG record databases, most of this work has focused on heartbeat arrhythmia detection based on ECG signal quality.

Human cytomegalovirus infection and its association with gestational diabetes mellitus during pregnancy.

Background: Infection is an important risk factor for gestational diabetes mellitus (GDM), while infection of human cytomegalovirus (HCMV) with GDM remains unclear and rarely reported. This study aimed to investigate the association of HCMV infection and serum inflammatory factor levels in pregnancy with GDM.

Methods: This prospective study included pregnant women who attended at Affiliated Hospital of Qingdao Hospital and Zibo Maternal and Child Health Hospital between December 2018 and August 2020.

Left Atrial Strain and Compliance Correlate with Diastolic Dysfunction Grades and Complications during Pre-eclampsia: A Speckle-Tracking Echocardiography Study.

This study aimed to investigate left atrium (LA) strain components in the assessment of cardiac function and its clinical correlates in pre-eclampsia (PE). With the use of speckle tracking echocardiography, phasic LA strain and (LASr)/(E/e'), the surrogate of LA compliance, were compared between healthy pregnant women (n = 70) and those with PE (n = 146) and among different diastolic dysfunction (DD) grades in PE. Receiver operating characteristic curves and logistic regression analysis were used to identify the role of strain components in distinguishing DD grades and predicting cardiac complications.

Identification of Differentially Expressed Plasma lncRNAs As Potential Biomarkers for Breast Cancer.

Background: Breast cancer is the most common malignant tumor in women and is not easy to diagnose. Increasing evidence has underscored that long non-coding RNAs (lncRNAs) play important regulatory roles in the occurrence and progression of many cancers, including breast cancer. We aimed to identify lncRNAs in plasma as potential biomarkers for breast cancer.

Atomic Layer Deposition (ALD) of Alumina over Activated Carbon Electrodes Enabling a Stable 4 V Supercapacitor Operation.

Designing high voltage (>3 V) and stable electrochemical supercapacitors with low self-discharge is desirable for the applications in modern electronic devices. This work demonstrates a 4 V symmetric supercapacitor with stabilized cycling performance through atomic layer deposition (ALD) of alumina (Al O ) on the surface of activated carbon (AC). The 20-cycle ALD Al O coated AC delivers 84 % capacitance retention after 1000 charge/discharge cycles under 4 V, contrary to the bare AC cells having only 48 % retention.

Interleukin-18 Is a Prognostic Marker and Plays a Tumor Suppressive Role in Colon Cancer.

Interleukin-18 (IL-18) belongs to the IL-1 family and is an essential proinflammatory and immune regulatory cytokine. The present study was designed to investigate the expression and function of IL-18 in colon cancer. In clinical analyses, mRNA and protein expressions of IL-18 were decreased in tissues of colon cancer patients.

Elevated RUNX1 is a prognostic biomarker for human head and neck squamous cell carcinoma.

Runt-related transcription factors regulate many developmental processes such as proliferation and differentiation. In this study, the function of the runt-related transcription factor 1 (RUNX1) was investigated in head and neck squamous cell carcinoma (HNSCC). Our results show that RUNX1 expression was elevated in HNSCC patients, which was greatly correlated with the N stage, tumor size, and American Joint Committee on Cancer stage.

Prevalence and Therapies of Antibiotic-Resistance in .

Infectious diseases are the second most important cause of human death worldwide; is a very common human pathogenic microorganism that can trigger a variety of infectious diseases, such as skin and soft tissue infections, endocarditis, osteomyelitis, bacteremia, and lethal pneumonia. Moreover, according to the sensitivity to antibiotic drugs, can be divided into methicillin-sensitive (MSSA) and methicillin-resistant (MRSA). In recent decades, due to the evolution of bacteria and the abuse of antibiotics, the drug resistance of has gradually increased, the infection rate of MRSA has increased worldwide, and the clinical anti-infective treatment for MRSA has become more difficult.

Anisotropic and strain rate-dependent mechanical properties and constitutive modeling of the cancellous bone from piglet cervical vertebrae.

Background And Objective: Characterizing the mechanical properties of the cancellous bone from the cervical vertebrae of child or child surrogate is important for the development of spine finite element models and the investigation of injury mechanism, however, there is currently no public data available as far as we know.

Methods: Compression tests were conducted on the specimens from the cervical vertebrae of 8-week-old piglets (child surrogates) in axial and radial directions at the strain rates of 0.01, 0.

Development, validation, and application of ligamentous cervical spinal segment C6-C7 of a six-year-old child and an adult.

Background And Objective: The cervical spine is one of the primary regions that is easily injured in traffic accidents. Although adult cervical spine finite element models have been widely adopted to investigate the cervical injury, few efforts have been made with respect to the development and application of FE models of the pediatric cervical spine, especially that of a six-year-old child. The objective of this study is to develop and validate high quality cervical spinal segment C6-C7 FE models of a six-year-old child and an adult, and to further investigate the differences of C6-C7 between the child and adult under different loading conditions.

Melatonin regulation as a possible mechanism for probiotic (VSL#3) in irritable bowel syndrome: a randomized double-blinded placebo study.

Background: Probiotics have treatment efficacy in irritable bowel syndrome (IBS), but the exact mechanism remains obscure. One hypothesis is the mediation of melatonin levels, leading to changes in IBS symptoms.

Aim: The purpose of this study was to evaluate the effects of a probiotic, VSL#3, on symptoms, psychological and sleep parameters, and pain sensitivity in IBS, and relate these parameters to in vivo melatonin levels.

CEUS helps to rerate small breast tumors of BI-RADS category 3 and category 4.

Purpose: The primary aim of this study was to explore if classification, whether using the BI-RADS categories based on CEUS or conventional ultrasound, was conducive to the identification of benign and malignant category 3 or 4 small breast lesions.

Material And Methods: We evaluated 30 malignant and 77 benign small breast lesions using CEUS. The range of enhancement, type of enhancement strength, intensity of enhancement, and enhancement patterns were independent factors included to assess the BI-RADS categories.

[Value of contrast-enhanced sonography in early diagnosis of breast cancer].

Objective: To assess the clinical value of contrast-enhanced ultrasonography (CEUS) in early diagnosis of breast cancer.

Methods: CEUS was performed in 107 cases of ultrasound BI-RADS(®) category 3 or category 4 small breast tumors (diameter no greater than 10 mm) before surgery. The range, type and patter of enhancement of the tumor and the surrounding tissues were observed, and the time-intensity curve (TIC) was analyzed for TIC curve type, basic and peak intensity, enhancement intensity, rising slope, and enhancement intensity.