Publications by authors named "Guanghao Yue"

Article Synopsis
  • Growth hormone-secreting pituitary neuroendocrine tumors are classified into two types: densely granulated (DGGH) and sparsely granulated (SGGH), with SGGH being more aggressive and having a worse prognosis.
  • Researchers conducted mA-sequencing on tumor samples and several assays to investigate the role of N-methyladenosine (mA) in these tumors and assessed potential therapies.
  • The study found reduced mA levels and increased expression of the demethylase FTO in SGGH tumors, leading to stabilized tumor growth, resistance to treatments, and revealing FTO as a potential therapeutic target for SGGH.
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Objective: Measurement of loop gain in patients with obstructive sleep apnea (OSA) is of great importance for determining the cause of OSA and realizing precision medicine. In this study, automatic measurement of loop gain is carried out during wakefulness based on the pseudorandom binary sequence (PRBS) CO stimulation method.

Methods: A respiratory data acquisition platform is designed and constructed to automate the processes of gas configuration, ventilatory stimulation with CO and data acquisition.

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