Publications by authors named "Guangdi Yin"
Int J Biol Macromol
December 2024
Article Synopsis
- This study investigates how phosphoglycerate mutase 1 (PGAM1) influences aerobic glycolysis and tumor aggressiveness in melanoma, suggesting it could be a target for new therapies.
- Researchers found that high levels of PGAM1 are associated with poor patient outcomes, as its silencing in melanoma cells reduced their proliferation, invasion, and glycolysis.
- The study concludes that PGAM1 plays a critical role in melanoma progression through its effects on apoptosis and immune response, highlighting potential pathways for therapeutic intervention.
