Publications by authors named "Guangchun Liu"

Article Synopsis
  • Breast cancer is a serious health risk for women, and traditional treatments often fall short, leading researchers to explore combination therapies for better outcomes.
  • This study developed an injectable hydrogel by crosslinking sulfhydryl-modified hyaluronic acid with polydopamine, allowing it to deliver chemotherapy drugs effectively while also serving as a photothermal agent.
  • The hydrogel demonstrated the ability to both deliver drugs consistently and enhance anti-tumor effects through photothermal therapy, resulting in reduced tumor growth and increased cell death without notable toxicity.
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Lumpectomy plus radiation is a treatment option offering better survival than conventional mastectomy for patients with early-stage breast cancer. However, successive radioactive therapy remains tedious and unsafe with severe adverse reactions and secondary injury. Herein, a composite hydrogel with pH- and photothermal double-sensitive activity is developed via physical crosslinking.

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The genus Conicera Meigen from China is revised. 35 species are recorded, of which 19 are new to science: C. obtusifinis sp.

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Cancer remains the leading cause of death worldwide. In spite of significant advances in targeted and immunotherapeutic approaches, clinical outcomes for cancer remain poor. The aim of the present study was to investigate the potential mechanisms and therapeutic targets of Frondoside A for the treatment of liver, pancreatic, and bladder cancers.

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The ant-parasitizing genus Pseudacteon Coquillett from China is revised. Nineteen species are recorded, of which nine are new to science: P. robustisetosus sp.

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The ant-parasitizing genus Microselia Schmitz, 1934 is reported for the first time from China. Two new species, M. longarista sp.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) continue to wreak havoc across the globe. Higher transmissibility and immunologic resistance of VOCs bring unprecedented challenges to epidemic extinguishment. Here we describe a monoclonal antibody, 2G1, that neutralizes all current VOCs and has surprising tolerance to mutations adjacent to or within its interaction epitope.

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and were two forensically important flies in relatively sealed environments. Their mitochondrial genomes were first sequenced, annotated, and phylogenetic analyses were performed with other 8 species of the Asehiza in this study. Maximum-likelihood phylogenetic tree revealed that Phoridae is closer to Platypezidae and Lonchopteridae within Diptera.

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The genus Epicnemis Borgmeier,1962 is firstly reported from Jiangxi Province, China, with description of a new species, E. linguiformis sp. nov.

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A new genus, , with two new species, and , is described from China. It belongs phylogenetically to the group of genera. The species Liu is transferred to the new genus.

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A new scuttle fly of the genus Pseudacteon Coquillett, P. trapeziformis, from Mt. Changbai, northeat China is described and illustrated.

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The genus Schmitz, 1923 is recorded from China for the first time. Three species are reported, namely , , and a new species here described, Some new morphological data are reviewed and illustrated for the first time, and an identification key to species present in China is presented.

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The Chinese species of Diplonevra are revised, with 16 recognised species from both the Oriental and Palaearctic parts of China. The following 8 species are described as new to science: D. corniculata sp.

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The genus Megaselia was established by Rondani in 1856 with the type species Megaselia crassineura Rondani (=Phora costalis Roser, 1840) (Borgmeier 1968). About 1600 species are recorded and distributed all over the world (Fang & Liu 2015). In the genus Megaselia, species with wing-spots are rare.

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A review of the genus Minilimosina Roháček, 1983 of China, comprising 16 species, is given, with data about types, published descriptions and figures, and distributions. A key to the Chinese species of the genus Minilimosina is provided and three new species are described and illustrated: M. gracilenta Su sp.

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The Chinese species of Dohrniphora are revised, with 27 recognised species from both Oriental and Palaearctic China. The following 14 species are described as new to science: D. rectangularis sp.

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Ultrasound has been successfully adopted to improve the biocatalytic properties of APE1547 (a novel esterase from the archaeon Aeropyrum pernix K1) in the resolution of ibuprofen. After optimizing the conditions (ultrasound power, 200 W; temperature, 35 °C), the best biocatalytic performance of APE1547 (enzyme activity, 5.39 µmol/H/mg; E value, 130.

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In addition to causing myiasis in humans and animals, Megaselia scalaris (Loew) has been reported as a forensically important fly. The determination of a minimum postmortem interval (PMI) often relies on the determination of the age of the larvae and pupae. The pupal stage represents about 50% of the immature development time and the pupal age may therefore serve as an important tool in entomological minimum PMI estimation.

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In addition to causing myiasis in humans, Megaselia spiracularis Schmitz has also been reported as a forensically important fly. The determination of a minimum post-mortem interval (PMI) often relies on the determination of the age of the larvae and pupae. The pupal stage represents about 50% of the immature development time and the pupal age may therefore serve as an important tool in entomological PMI estimation.

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The widely used antibiotic metronidazole (MTZ) was investigated for its toxic effects on the liver of the common carp (Cyprinus carpio L.). The fish were exposed to 0.

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Morphology of all larval instars and puparium of Dohrniphora cornuta (Bigot), a most common phorid fly species indoors in China, is presented using scanning electron microscopy. The first instar larva was composed of 12 segments, each of segments 3-11 with six slender tubercles situated dorsally, dorsolaterally, and laterally in transverse row. These tubercles divided into two segments, of which the basal one was smooth, and the brush-shaped distal one was comprised of a cluster of fine spines.

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Morphology of all larval instars and puparium of Diplonevra peregrina, a most common phorid fly species indoors in China, is presented using scanning electron microscopy. The first instar larva was composed of 12 segments, each of segments 3-11 with six spicate tubercles situated dorsally, dorsolaterally, and laterally in transverse row. The dorsal tubercles were much longer than the laterals and dorsolaterals.

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