Weighted Gene Coexpression Network Analysis Reveals Essential Genes and Pathways in Bipolar Disorder.

Bipolar disorder (BD) is a major and highly heritable mental illness with severe psychosocial impairment, but its etiology and pathogenesis remains unclear. This study aimed to identify the essential pathways and genes involved in BD using weighted gene coexpression network analysis (WGCNA), a bioinformatic method studying the relationships between genes and phenotypes. Using two available BD gene expression datasets (GSE5388, GSE5389), we constructed a gene coexpression network and identified modules related to BD.

[The indication of bone scan for patients with newly diagnosed prostate cancer].

Objective: To investigate the indication of bone scan for patients with newly diagnosed prostate cancer.

Methods: The clinical data of continual 95 patients with newly diagnosed prostate cancer was involved between January 2006 and December 2010. The relationship between age, PSA, Gleason scores, clinical stage and positive bone scans was respectively compared.

Effect of Si-Miao-Yong-An on the stability of atherosclerotic plaque in a diet-induced rabbit model.

Ethnopharmacological Relevance: Si-Miao-Yong-An (Trade name: Mai-Luo-Ning), a Chinese herbal formulation comprising Flos Lonicerae Japonicae, Radix Scrophulariae Ningpoensis, Radix Angelicae Sinensis and Radix Glycyrrhizae Uralensis, has been used in treating ischemic cardiovascular and cerebrovascular diseases for many years. Clinical and experimental studies have shown that Si-Miao-Yong-An can inhibit the inflammatory response and antagonize the blood clotting process.

Aim Of The Study: To investigate the effect of Si-Miao-Yong-An on atherosclerotic plaque stability in rabbit model.

[Measuring and analyzing infrared spectrum of periodically polarized lithium niobate].

The present paper reports theoretical and experimental research on the tunable output characteristics of periodically polarized lithium niobate. We made six equal distance crystal grating sections, with each distance being 0.5 mm and the polarization period range of 29.

[Calculation of spectroscopic properties of Tm:YVO4 crystals].

Sigma and pi polarized absorption spectra of Tm:YVO4 crystal have been measured at room temperature. Considering the difference of the sigma and pi polarized absorption spectra and the changing of the refractive index with different wavelengths, we calculate the intensity parameters of Tm3+ in crystal YVO4 which are omega 2 = 1.9416 x 10(-20) (cm2), omega 4 = 0.

[Research of image spectrometer using linear variable interference filter].

In the present work we have designed a small-size portable imaging spectrometer using linear variable interference filter, with CCD camera as picture sensor, and micromotion stage to bring along interference filter which scan across every pixel of CCD array. The difference column pixel in the picture which we get at every step is monocolour partial image under different wavelength, with the step by step, these column monocolour pixels change the wavelength. And finally we reassembled these images and get the whole monocolour image with different wavelength.

Comparison of the solutions from a novel variational method with numerical results for the study of beam propagation in a Kerr medium with nonlinear absorption.

We present results from a novel variational method for the study of beam propagation in a Kerr medium with nonlinear absorption. This new method combines the variational method and a nonlinear absorption equation and gives a concise expression for the combination. The results obtained with this method show good quantitative agreement with numerical solutions obtained with the finite-difference method.

Variational analysis of z scan of thick medium with an elliptic Gaussian beam.

By variational approach, we analyze the characteristics of beam propagation through a cubic optical nonlinear medium using a laser beam that has a transverse elliptic Gaussian profile. The analytic solution to the normalized transmittance at the center of the far field as a function of medium position and the beam characteristics is obtained and compared with the numerical simulation, which is realized by a combination of algorithms. We also analyze the peak-valley transmittance difference as a function of medium length, ellipticity, and a stigmatism.

Narrow-linewidth widely tunable hybrid Q-switched double-clad fiber laser.

A laser-diode-pumped Yb-doped double-clad fiber laser operating in a hybrid Q-switched regime has been demonstrated. With pulsed pump light and stimulated Brillouin scattering of the gain fiber as the Q-switching mechanisms, the laser generated nanosecond pulses with a stable repetition rate. A single-pulse energy of as much as 143.