Publications by authors named "Guang-xia Shi"

Introduction: Atrial fibrillation (AF) is the prevalent cardiac arrhythmia and can significantly impair the quality of life (QoL). Although catheter ablation (CA) is an established treatment for AF,post-procedural complications or perceived inadequate control of AF may diminish the QoL for some patients, potentially even to levels lower than pre-procedure. Preliminary findings from our previous pilot trial indicate that acupuncture may positively influence QoL in AF patients post-CA.

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  • - The study evaluates how common steatotic liver disease (SLD) is among US adolescents, focusing on identifying metabolic dysfunction-associated steatotic liver disease (MASLD) and its link to clinically significant fibrosis (CSF).
  • - Out of 1,446 adolescents, 20.1% had SLD, with the majority (17.9%) diagnosed with MASLD, while only 4% had CSF.
  • - Although a high percentage of SLD patients met the MASLD criteria, there was no significant difference in the risk of CSF between those with and without MASLD.
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Importance: Sciatica is commonly caused by herniated lumbar disc and contributes to severe pain and prolonged disability. Although acupuncture is widely used by patients with chronic sciatica, the evidence of its efficacy is scarce.

Objective: To investigate the efficacy and safety of acupuncture compared with sham acupuncture in patients with chronic sciatica from herniated disk.

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Chronic neuropathic pain has been one of the prominent causes of disability, and acupuncture has shown promise in treatment. The present study aimed to characterize acupuncture modulation of chronic neuropathic pain and explore the related functional brain changes. Sixty chronic sciatica patients were divided into acupuncture- or sham acupuncture groups and received 10 sessions of treatment during 4 weeks.

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  • The study investigates the clinical and cost-effectiveness of electroacupuncture versus exercise for treating knee osteoarthritis (KOA) in middle-aged and older patients, as both therapies show substantial benefits but lack clear comparison data.
  • A randomized controlled trial will involve 196 KOA patients, assigning them equally to either an electroacupuncture group (receiving treatment 3 times a week for 8 weeks) or an exercise group (participating in neuromuscular training twice a week for 8 weeks), with education on KOA management given to both groups.
  • Results will assess various outcomes, including pain relief and quality of life, to offer insights on the effectiveness of each treatment option and help tailor therapies to meet individual patient needs
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Objective: Converging evidence indicates that subjective cognitive decline (SCD) could be an early indicator of dementia. The hippocampus is the earliest affected region during the progression of cognitive impairment. However, little is known about whether and how acupuncture change the hippocampal structure and function of SCD individuals.

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In order to explore the application of "patient and public involvement" (PPI) in acupuncture clinical research, the connotation, reporting standards and research status of PPI at home and abroad are collated, and the key problems of PPI encountered in acupuncture clinical research are deeply considered and summarized. It is suggested that the short-form checklist of (GRIPP) of the 2nd edition should be applied to acupuncture clinical research. PPI provides a new perspective for acupuncture clinical research.

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Purpose: Acupuncture has been widely used in the treatment of knee osteoarthritis (KOA), but the selection of acupoints is indeterminate and lacks biological basis. The skin temperature of acupoints can reflect the state of local tissue and may be a potential factor for guiding acupoint selection. This study aims to compare the skin temperature of acupoints between KOA patients and the healthy population.

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Chronic pain has been one of the leading causes of disability. Acupuncture is globally used in chronic pain management. However, the efficacy of acupuncture treatment varies across patients.

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  • Renal colic is a painful condition, and this study aimed to analyze if acupuncture could enhance pain relief when used alongside traditional analgesics in patients experiencing acute renal colic.
  • Conducted in a Chinese emergency department, the randomized trial involved 80 participants with significant pain, comparing the effects of acupuncture against sham acupuncture following an intramuscular injection of diclofenac sodium.
  • Results showed that acupuncture led to a much higher pain relief response rate at 10 minutes (77.5%) compared to sham acupuncture (10.0%), although no significant differences were observed regarding the need for additional pain relief medication.
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Introduction: Hypertension is a common risk factor for cardiovascular disease. Transcutaneous electrical acupoint stimulation (TEAS) may be effective for hypertension, but the evidence remains limited. The aim of this study is to evaluate the effectiveness and safety of the smart phone-based TEAS as adjunctive therapy for hypertension.

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  • The study examined the effectiveness of a home-based treatment combining transcutaneous electrical acupoint stimulation (TEAS) and lifestyle changes on controlling blood pressure in individuals with high-normal BP.
  • Participants were divided into two groups: one receiving the combined treatment (TEAS + lifestyle changes) and the other just lifestyle changes, over 12 weeks.
  • Results showed a significant reduction in systolic blood pressure in the intervention group, though no change in body mass index or quality of life was observed, and few participants reported adverse effects related to TEAS.
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  • Postoperative ileus is a common issue following colorectal surgery that prolongs recovery and negatively affects patients' overall wellbeing.
  • A study was conducted on colorectal cancer patients to assess the impact of electroacupuncture at specific acupoints combined with standard care on postoperative recovery.
  • The results showed that electroacupuncture at the ST36 point significantly reduced the time to first flatus and defecation compared to standard care alone, while acupuncture at ST25 showed no substantial benefits.
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  • Chronic Sciatica is a painful condition with significant impacts on health and quality of life, and current treatments are ineffective long-term, prompting this study on acupuncture's potential benefits.
  • The study involves 216 patients, randomly assigned to receive either real or sham acupuncture, with treatment over 4 weeks and follow-ups extending to 52 weeks to evaluate pain and disability outcomes.
  • The trial is ethically approved, will gather informed consent from participants, and aims to publish its findings in peer-reviewed journals to share results with the medical community.
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Purpose: Activation of muscarinic receptors located in bladder sensory pathways is generally considered to be the primary contributor for driving the pathogenesis of neurogenic detrusor overactivity following spinal cord injury. The present study is undertaken to examine whether moxibustion improves neurogenic detrusor overactivity via modulating the abnormal muscarinic receptor pathway.

Materials And Methods: Female Sprague-Dawley rats were subjected to spinal cord injury with T9-10 spinal cord transection.

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Metabolic syndrome (MS) is a clinical syndrome with multiple metabolic disorders. As the diagnostic criteria for MS still lacking of imaging laboratory method, this study aimed to explore the differences between healthy people and MS patients through infrared thermography (IRT). However, the observation region of the IRT image is uncertain, and the research tried to solve this problem with the help of knowledge mining technology.

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Background: Current evidence suggests that acupuncture is an effective adjunctive therapy that can bring potential benefits to patients with cardiac arrhythmias. However, there are relevant gaps in the optimal therapeutic strategy, which may cause uncertainties on the best practice of acupuncture treatment for arrhythmia. We aim to develop consensus-based recommendations for clinical guidance on acupuncture treatment of cardiac arrhythmias.

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Taking the clinical trial of acupuncture in treatment of postprandial distress syndrome as an example, this paper proposes that the acupuncture clinical trial protocol should be optimized in view of acupuncture prescription, acupuncture frequency and outcomes. Besides, the data quality of acupuncture clinical trial should be improved in consideration of data sharing and electronic data capture so as to provide a reference for the majority of researchers to optimize and implement acupuncture clinical trial.

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  • Constipation is a common side effect of antipsychotic medications, and there is a need for better management strategies, prompting a study on electro-acupuncture (EA) as a potential solution.
  • The study is a randomized controlled trial involving 112 participants, comparing the effects of EA to sham acupuncture over 22 weeks, measuring outcomes like bowel movement frequency and constipation symptoms.
  • Results will contribute to the understanding of EA's safety and effectiveness for treating constipation linked to antipsychotic use, and will be published in peer-reviewed journals for wider accessibility and reliability.
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A close relationship between knee osteoarthritis (KOA) and gut microbiota has recently been described. Herein, we aim to investigate the effect of electroacupuncture (EA) on gut microbiota in participants with KOA. We conducted a study of 60 participants with KOA and 30 matched healthy controls (HCs).

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Background: Acute renal colic caused by urinary calculi (ARCUC) has a considerable impact on the quality of life. Acupuncture might be a potential treatment option. However, the evidence is limited.

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Acupuncture may be a promising complementary therapy for vascular cognitive impairment (VCI) and has been extensively applied in China. However, its potential effects remain uncertain, and the clinical findings are inconsistent. This review aimed to systematically appraise the overall effectiveness and safety of acupuncture in treating VCI.

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